Prognostic importance of CD47 expression on survival of colorectal cancer
Aktepe Oktay Halit 1, Kurtulan Olcay 2, Dama Pinar Ezgi 1, Yildirim Eda Caliskan 3, Terzi Aytac 1, Kalyoncu Simin Alara 4, Atag Elif 1, Yavuzsen Tugba 1, Uner Meral 2, Karaoglu Aziz 1, Yalcin Suayib 5
1 https://ror.org/00dbd8b73 Department of Medical Oncology Dokuz Eylül University 35330 Balcova Izmir Turkey
2 https://ror.org/04kwvgz42 Department of Pathology, Faculty of Medicine Hacettepe University Ankara Turkey
3 https://ror.org/030z8x523 Department of Medical Oncology Sincan Research and Training Hospital Ankara Turkey
4 https://ror.org/00dbd8b73 Department of Internal Medicine, Faculty of Medicine Dokuz Eylül University Izmir Turkey
5 https://ror.org/04kwvgz42 Department of Medical Oncology Hacettepe University Cancer Institute Ankara Turkey
Abstract
Background The exact value of cluster of differentiation 47 (CD47), known as the “don’t eat me” signal, in colorectal cancer (CRC) has not been clearly revealed. Thus, we investigated the impact of its expression on the overall survival (OS) of CRC patients who underwent colectomy.
Methods Ninety-eight CRC patients were included. The patient population was grouped into two categories based on the median value of CD47 expression examined...
