The relationship between sleep quality, fatigue, and depressive symptoms in maintenance hemodialysis patients: a cross-lagged analysis
- Published on 02/25/2026
- Reading time: 6 min.
Tan Hong 1, Ma XiaoLan 1, Zhang HuiZe 1, Zhang YiPei 1, Li Li 2,3
1 https://ror.org/01p455v08 School of Nursing Xinjiang Medical University Urumqi Xinjiang China
2 https://ror.org/02qx1ae98 Department of Urology The First Affiliated Hospital of Xinjiang Medical University 830054 Urumqi Xinjiang China
3 Health Care Research Center for Xinjiang Regional population Urumqi Xinjiang China
Abstract
Background Sleep quality, fatigue, and depressive symptoms are highly prevalent and frequently co-occur as a symptom cluster in maintenance hemodialysis (MHD) patients. This cluster significantly impairs patients’ health-related quality of life and increases mortality risk. Although cross-sectional studies suggest interconnections, the temporal dynamics and interrelationships within this triad remain unclear, particularly regarding gender differences. Therefore,...
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