Clinical Impact and Cost-effectiveness of Everolimus Combination Therapy in Liver Transplant Recipients: Focus on the Risk of Cancer, Infection, and Renal Function.

  • Published on 07/29/2026
  •  Reading time: 1 min.

Jang, Suk-Chan PharmD, PhD; Kim, Gi-Ae MD, PhD; Lim, Young-Suk MD, PhD; Kim, Hye-Lin PhD; Lee, Eui-Kyung PhD

Abstract

Background. Post-liver transplant complications-cancer, infections, and renal dysfunction-impose substantial clinical and economic impact on recipients. This study evaluated clinical impacts and cost-effectiveness of adding everolimus (EVR) to a calcineurin inhibitor (CNI)-based regimen in liver transplant recipients, aiming to identify how co-occurring major complications affect cost-effectiveness.

Methods. We conducted a cohort analysis and a cost-utility analysis,...

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