A comparative analysis of drug-induced kidney injury adverse reactions between cyclosporine and tacrolimus based on the FAERS database
- Published on 05/07/2025
- Reading time: 6 min.
Xu Min 1, Xu Shanggang 2, Yi Xueliang 2
1 https://ror.org/034z67559 Department of Respiratory Clinical Medical College & Affliated Hospital of Chengdu University, Chengdu University 610036 Chengdu China
2 https://ror.org/034z67559 Department of Emergency Clinical Medical College & Affliated Hospital of Chengdu University, Chengdu University 610036 Chengdu China
Abstract
Background This study utilizes the FDA Adverse Event Reporting System (FAERS) database to compare the adverse reaction signals of cyclosporine and tacrolimus, two widely used immunosuppressants, in relation to drug-induced kidney injury. The findings aim to inform clinical decision-making.
Methods The study retrospectively analyzed data from January 2004 to September 2024, employing both frequency analysis and Bayesian methods. We assessed and compared...
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