Whole-body CT scanning radiation improves the immune microenvironment of tumor tissues to enhance the antitumor effect of ICI
- Published on 05/06/2025
- Reading time: 6 min.
Dong Jigang 1,2, Qi Ying 2, Sha Sha 2, Fu Chengrui 1,3, Xu Xiao 4, Li Baosheng 1,5,6,7,8
1 https://ror.org/0152hn881 Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy 300000 Tianjin China
2 Qingdao People’s Hospital Group (Jiaozhou) Jiaozhou Central Hospital of Qingdao Qingdao China
3 https://ror.org/01413r497 Department of Radiotherapy Shandong Cancer Hospital 250000 Jinan China
4 Qingdao People’s Hospital Group (Jiaozhou) Jiaozhou Central Hospital of Qingdao Qingdao China
5 https://ror.org/0152hn881 Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer Tianjin China
6 https://ror.org/0152hn881 Key Laboratory of Cancer Prevention and Therapy Tianjin’s Clinical Research Center for Cancer, Department of Radiation Oncology Tianjin China
7 https://ror.org/01413r497 Medical University; Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Jinan China
8 https://ror.org/042pgcv68 Academy of Medical Sciences No. 440 Jiyan Road 250017 Jinan China
Abstract
Objective The effect of frequent whole-body CT scans during immune checkpoint inhibitor (ICI) therapy on patients' anti-tumor immunity.
Methods We conducted a retrospective clinical study aimed to investigate the correlation between the frequency of CT scans during immune checkpoint inhibitor (ICI) therapy and the duration of remission (DOR) of ICI therapy in patients with stage IV non-small cell lung cancer (NSCLC). We constructed a hormonal mouse model...
To continue reading this article in Full-Text...
Peer-Reviewed Journals A-Z
Search | Advanced search
Get the latest news in Oncology
Receive our newsletter to stay up to date with the latest news in Oncology
