Targeting ferroptosis in melanoma: cancer therapeutics

  • Published on 06/09/2025
  •  Reading time: 9 min.

Khorsandi Khatereh 1, Esfahani HomaSadat 1, Ghamsari Saeedeh Keyvani- 2, lakhshehei Parisa 3

1 Department of Photodynamics, Medical Laser Research Center Yara Institute, ACECR Tehran Iran
2 Department of Microbiology Karaj Branch, Islamic Azad University Karaj Iran
3 Department of Biochemistry, Faculty of Biological Sciences North Tehran Branch, Islamic Azad University Tehran Iran

Abstract

Melanoma is an aggressive kind of skin cancer; its rate has risen rapidly over the past few decades. Melanoma reports for only about 1% of skin cancers but leads to a high majority of skin cancer deaths. Thus, new useful therapeutic approaches are currently required, to state effective treatments to consistently enhance the overall survival rate of melanoma patients. Ferroptosis is a recently identified cell death process, which is different from autophagy, apoptosis, necrosis,...

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