Complete/Near-Complete Itch Response Observed in Patients with Moderate-to-Severe Atopic Dermatitis Initiating Dupilumab: 3-Year, Real-World, Interim Data from the PROSE Registry

  • Published on 06/01/2026
  •  Reading time: 4 min.

Neal Bhatia   1 , Charles W. Lynde 2 ,3 , Kwinten Bosman 7  

1 Therapeutics Clinical Research, San Diego, CA, USA
2 University of Toronto, Markham, ON, Canada
3 Lynderm Research, Markham, ON, Canada
7 Sanofi, Paris, France

Abstract

Introduction Atopic dermatitis (AD) is a chronic, relapsing disease that can start at any age and has a significant negative impact on quality of life, including a significant itch burden. Here we report the proportion of patients in a real-world study achieving a complete/almost complete resolution of itch, as measured by the Peak Pruritus Numeric Rating Scale (PP-NRS) and improvement in overall disease severity score (ODS), in patients aged12 years...

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