Distinguishing AKI from CKD: outcomes and characteristics of patients with abnormal serum creatinine and no known baseline
- Published on 02/25/2026
- Reading time: 4 min.
Wong Esther 1,2, Casula Anna 1, Hughes Rachael 2, Cornish Rosie 2, Tilling Kate 2, Selby Nicholas M. 5,6, Medcalf James 1,3,4
1 https://ror.org/01zpyjx73 UK Renal Registry, UK Kidney Association Bristol UK
2 https://ror.org/0524sp257 University of Bristol Bristol UK
3 https://ror.org/02fha3693 University Hospitals of Leicester NHS Trust Leicester UK
4 https://ror.org/04h699437 University of Leicester Leicester UK
5 https://ror.org/01ee9ar58 University of Nottingham Nottingham UK
6 https://ror.org/04w8sxm43 University Hospitals of Derby and Burton NHS Foundation Trust Derby UK
Abstract
Background Comparison of a patient’s abnormal serum creatinine result to an earlier value is fundamental to differentiating Acute Kidney Injury (AKI) from Chronic Kidney Disease (CKD), and is the first step in electronic AKI detection systems. For those patients in whom a baseline serum creatinine is unavailable, some systems generate a warning message to highlight the elevated serum creatinine but without distinguishing AKI from CKD (a “?AKI?CKD”...
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