Association between thyroid hormone index TFQIFT3 and diabetic peripheral neuropathy: a retrospective cross-sectional analysis in euthyroid individuals with type 2 diabetes

  • Published on 02/25/2026
  •  Reading time: 5 min.

Xu Weiwei 1, Li Lian 1, Cai Jiasheng 2,2, Liu Yichen 1, Han Chenyu 1, Ye Xiaomei 1, Yi Jufen 1, Zhang Min 1

1 https://ror.org/037p24858 Department of Endocrinology and Metabolism Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University 1158 Park East Road 201700 Shanghai China
2 https://ror.org/037p24858 Department of Cardiovascular Medicine Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University 1158 Park East Road 201700 Shanghai China

Abstract

Background The relationship between thyroid hormone sensitivity and diabetic peripheral neuropathy (DPN) remains unclear. The Thyroid Feedback Quantile-based Index using FT3 (TFQIFT3) is considered a sensitive marker of peripheral thyroid hormone activity. This study aimed to investigate the association between TFQIFT3 and DPN in euthyroid individuals with type 2 diabetes mellitus (T2DM).
Methods This retrospective cross-sectional study analyzed euthyroid...

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