Alzheimer disease ATN imaging biomarkers across type 2 diabetes mellitus stages in diverse populations

  • Published on 06/03/2026
  •  Reading time: 1 min.

Malavika Pillai 1, Beau Ances 1, Sid E. O'Bryant 2, Karin L. Meeker 1

1 Washington University in St. Louis School of Medicine, St. Louis, MO USA
2 University of North Texas Health Science Center, Fort Worth, TX USA

Abstract

Background Type 2 diabetes mellitus (T2DM) is a risk factor for Alzheimer disease (AD) and disproportionately impacts under‐represented groups including Mexican Americans/Hispanics (MAs) and African Americans/Blacks (AAs) compared to non‐Hispanic Whites (NHWs). However, it remains unclear how amyloid, tau, and neurodegeneration (AT(N)) AD imaging biomarkers and cognitive functioning differ across diabetic stages including non‐diabetes, pre‐diabetes,...

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