MiR-483-5p has the potential to serve as a biomarker in perioperative respiratory adverse events in children under general anesthesia
- Published on 03/02/2026
- Reading time: 4 min.
Zhao Xingxing 1, Yan Ruiqi 2, Liu Jun 3, Han Xiaotong 3, Ma Xiaoning 4, Li Min 5, Yang Yuelai 6
1 https://ror.org/0156rhd17 Department of Anaesthesia and Perioperative Medicine The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University 325027 Wenzhou China
2 https://ror.org/01nnwyz44 Department of Anesthesiology Shanghai Public Health Clinical Center 201508 Shanghai China
3 https://ror.org/03cmqpr17 Department of Anesthesiology Affiliated Hospital of Gansu Medical College (People’s Hospital of Pingliang) 744000 Pingliang Gansu China
4 https://ror.org/03cmqpr17 Operating Room, Affiliated Hospital of Gansu Medical College (People’s Hospital of Pingliang) 744000 Pingliang Gansu China
5 https://ror.org/03cmqpr17 Department of Nursing Affiliated Hospital of Gansu Medical College (People’s Hospital of Pingliang) No. 296, Kongtong East Road, Kongtong District 744000 Pingliang Gansu Province China
6 https://ror.org/010826a91 Department of Anesthesia Nursing Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine No. 639, Zhizaoju Road, Huangpu District 200011 Shanghai China
Abstract
Background Perioperative respiratory adverse events (PRAE) may cause critical illness in children undergoing anesthesia and surgery. So, this study aims to explore the diagnostic value of miR-483-5p in PRAE.
Methods This study included 112 patients with PRAE and 93 patients without PRAE. MiR-483-5p expression was quantified utilizing RT-qPCR. The receiver operating characteristic (ROC) curve was utilized to assess the diagnostic value. The clinicopathological...
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