Histopathological characteristics of secondary enucleation after iodide-125 plaque radiotherapy in Chinese patients with uveal melanoma
- Published on 05/04/2026
- Reading time: 6 min.
Haihan Zhang1,2, Heng Wang1,3, Yueming Liu3, Jingting Luo1,4, Shiyi Yin1,4, Xiaolin Xu3, Wenbin Wei1,3,4
1
Beijing Tongren Eye Center, Beijing, China
2
Eye Hospital of Shandong First Medical University, Jinan, China
3
Beijing Tongren Eye Centre, Beijing Tongren Hospital, Beijing, China
4
Capital Medical University, Beijing, China
Correspondence to Dr Wenbin Wei; weiwenbintr@163.com; Dr Xiaolin Xu; drxuxiaolin@163.com
Abstract
Purpose To explore the histopathological characteristics in eyes with uveal melanoma (UM) that had secondary enucleation after iodine-125 plaque radiotherapy (PRT).
Methods This study included 243 patients with unilateral UM treated at Beijing Tongren Hospital from 2007 to 2020. Of these, 119 initially received PRT, followed by enucleation 2 months–9 years later. We retrospectively examined the histopathological features of enucleated ocular tissues...
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