Activation of the Integrin αV-YAP-CTGF Axis in Liver Sinusoidal Endothelial Cells Promotes Liver Fibrogenesis, Leading to Portal Hypertension and Liver Carcinogenesis in Congestive Hepatopathy

Published on 05/04/2026

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Kato, Seiya; Hikita, Hayato; Tsukamoto, Osamu; Sato, Katsuhiko; Kamizono, Kohei; Sasaki, Yoichi; Fukumoto, Kenji; Myojin, Yuta; Murai, Kazuhiro; Tahata, Yuki; Makino, Yuki; Saito, Yoshinobu; Kodama, Takahiro; Motooka, Daisuke; Kobayashi, Shogo; Yokoi, Hideki; Mukoyama, Masashi; Kubota, Yoshiaki; Tatsumi, Tomohide; Eguchi, Hidetoshi; Takehara, Tetsuo.

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Activation of the Integrin αV-YAP-CTGF Axis in Liver Sinusoidal Endothelial Cells Promotes Liver Fibrogenesis, Leading to Portal Hypertension and Liver Carcinogenesis in Congestive Hepatopathy

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