Hypertension: Archives News of the month
Harnessing NLRX1: a new frontier in mitigating inflammation in pulmonary hypertension
Hypertension 6 min.
Hypoxic pulmonary hypertension (HPH) is a condition characterized by elevated pulmonary artery pressure due to prolonged exposure to a hypoxic environment. It is prevalent among individuals residing at high altitudes and those with chronic obstructive pulmonary disease [1]. Pulmonary vascular remodeling...
Antibiotic-driven and microbiota-targeted therapy for advanced management of pulmonary hypertension
Hypertension 5 min.
Pulmonary hypertension (PH) is a progressive and life-threatening condition characterized by elevated pulmonary arterial pressure and vascular remodeling, ultimately leading to right heart failure and premature death. Among its various classifications, PH secondary to hypoxic lung diseases, such as chronic...
Is splenectomy one of the contributory factors to pulmonary hypertension? An analysis of splenectomized hemolytic anemia and immune thrombocytopenia patients
Hypertension 5 min.
Due to the anatomical and functional characteristics of the spleen, variable short- and long- term complications may occur after splenectomy. Vascular complications after splenectomy, including PH, have been reported [1, 2–3]. PH is a physiopathologic disorder that involves multiple clinical conditions...
Role of lipid droplets in pulmonary arterial hypertension: focusing on pulmonary artery smooth muscle cell proliferation
Hypertension 8 min.
PAH is widely recognized as a vascular lesion caused by structural changes driven by excessive proliferative growth in endothelial cells, vascular smooth muscle cells (SMCs) and inflammatory responses. According to incomplete statistics, up to 100 million people worldwide are strongly affected by...
Blood pressure at age 40 and key features of cerebral small vessel disease at age 70: data from the ACE 1950 Study
Hypertension 6 min.
Cerebral small vessel disease (cSVD) is a common ageing phenomenon [1, 2–3], and is associated with an increased risk of cerebrovascular events, cognitive decline [4, 5, 6–7], and dementia [8, 9, 10–11]. Increased blood pressure is associated with cSVD development, with neuroimaging...
