Peripheral Neuropathies: Archives News of the month
Heart rate variability tests for diagnosing cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus in advanced stages of kidney disease
Peripheral Neuropathies 5 min.
Cardiovascular autonomic neuropathy (CAN) is one of diabetes neuropathies, which represents the most prevalent, underdiagnosed and undertreated diabetes complication [1]. CAN is a degenerative condition that affects 16.7-34.3% patients with diabetes mellitus (DM), with a multifactorial pathogenesis,...
Safety and feasibility of deep brain stimulation of the anterior cingulate and thalamus in chronic refractory neuropathic pain: a pilot and randomized study
Peripheral Neuropathies 5 min.
Moderate to severe neuropathic pain (NP) has a prevalence of 5,1% in the general population [1]. Independently of pain intensity and duration, patients with NP report a huge impairment of quality of life and anxiety/depression scores, significantly higher than patients without pain or than patients suffering...
Anterior ischemic optic neuropathy in patients treated with semaglutide: report of four cases with a possible association
Peripheral Neuropathies 4 min.
Nonarteritic anterior ischemic optic neuropathy (NAION) is a leading cause of sudden vision loss, primarily affecting middle-aged and elderly individuals. Its hallmark features are an acute unilateral painless onset of visual impairment, relative afferent pupillary defect (RAPD) and hyperemic optic disc...
Effect of high-dose N-acetyl cysteine on the clinical outcome of patients with diabetic peripheral neuropathy: a randomized controlled study
Peripheral Neuropathies 7 min.
Diabetic peripheral neuropathy (DPN) is the most frequent long-term microvascular consequence of diabetes mellitus (DM) encompassing a wide spectrum of clinical and subclinical symptoms that are linked to loss of peripheral nerve fibers [1]. It is one of the most challenging diabetes complications to...
Increased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway
Peripheral Neuropathies 11 min.
Neuropathic pain is a chronic condition caused by nerve injury or disease, characterized by hyperexcitability in somatosensory nociceptive circuits that severely affects quality of life [1, 2]. Despite extensive research, effective treatments for this debilitating condition remain limited in clinical...
