In Vitro DiagnosticsArchives
Validation of an automated, end-to-end metagenomic sequencing assay for agnostic detection of respiratory viruses
In Vitro Diagnostics 1 min.
In Vitro Diagnostics
1 min.
Published on 07/07/2025 |
Original article (Full-text)
| Nick P G Gauthier et al. | The Journal of infectious diseases 2024; aop: 10.1093/infdis/jiae226
Current molecular diagnostics are limited in the number and type of detectable pathogens. Metagenomic next generation sequencing (mNGS) is an emerging, and increasingly feasible, pathogen-agnostic diagnostic approach. Translational barriers prohibit the widespread adoption of this technology in clinical...
Development and validation of multiplex real-time PCR for simultaneous detection of six bacterial pathogens causing lower respiratory tract infections and antimicrobial resistance genes
In Vitro Diagnostics 6 min.
In Vitro Diagnostics
6 min.
Published on 07/07/2025 |
Original article (Full-text)
| Dung Tran Thi Ngoc et al. | BMC Infectious Diseases 2024; 24(1): 164
Lower respiratory tract infections (LRTIs) are a leading infectious cause of morbidity and mortality globally. It is estimated that 336 million episodes of LRTIs occurred in 2016, resulting in nearly 2.4 million deaths of all ages [1]. Although viruses such as influenza viruses and respiratory syncytial...
