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Stress-experienced monocytes/macrophages lose anti-inflammatory function via β2-adrenergic receptor in skin allergic inflammation

 Published on 15/09/2025 |  Original article (Full-text)  | Urakami, Hitoshi et al. | The Journal of allergy and clinical immunology 2025; 155(3): 865-79

Psychological stress can exacerbate the development of allergies; however, the underlying mechanisms remain poorly understood. IgE-mediated cutaneous allergic inflammation (IgE-CAI) is a basophil-dependent skin allergy with eosinophil infiltration at inflammatory sites. Its resolution involves anti-inflammatory...

Exploring skin aging-associated genotypes; Moving toward delivery of precision medicine-based care more than beyond skin deep care: a genome-wide association study.

 Published on 08/09/2025 |  PubMed  | Khashei Varnamkhasti Samire et al. | BMC geriatrics 2025 May; 25(1): 307

Oxidative damage is the principal cellular disturbance in the skin aging. Missense polymorphisms strengthen or weaken detoxification enzyme activity. Determination of deleterious functional effects of polymorphisms in detoxification genes (NQO1 and EPHX1) in skin aging was the overall purpose of conducting...

Pollution, a Relevant Exposome Factor in Skin Aging and the Role of Multi-benefit Photoprotection.

 Published on 01/09/2025 |  PubMed  | Santamaria J et al. | Actas dermo-sifiliograficas 2025 Jun; 116(6): 611-620

Skin aging is a complex, continuous, multifactorial process resulting from cumulative morphological and functional changes in the skin over time. This happens because of two processes: intrinsic and extrinsic skin aging. Intrinsic skin aging occurs naturally over time and reflects each person's genetic...

A Dynamic, High-Stretch Resilient Hyaluronic Acid Filler Improves Fine Lines of the Cheek and Patient-Reported Outcomes.

 Published on 25/08/2025 |  Original article (Full-text)  | Alzahrani, Fatmah MD et al. | Dermatologic Surgery. Volume 51(8).

Radial cheek lines develop over time due to ultraviolet exposure, dynamic expression, loss of skin elasticity, and superficial fat due to aging. With the aging population and increasing social awareness, there is a surge in demand for treatment. OBJECTIVE: The purpose of this study was to evaluate efficacy...