
Skin aging is an ongoing process that is far from uniform and influenced by a complex interplay of variables such as sun exposure, tobacco use, skin phototype, as well as genetics. Ongoing research continues to elucidate novel intrinsic mediators of skin aging with the goal of broadening the scope of...

The diabetes mellitus is a complex metabolic disease that occurs due to a deficiency in the synthesis of insulin or the functioning of insulin receptors, which leads to high blood glucose levels. Diabetes is a serious health problem that impacts 537 million adults around the world. It has been estimated...

Ultraviolet (UV)‐radiation (UVR) is known to be the predominant cause of human skin cancer since UVR‐induced DNA damage plays a key role in the initiation phase of skin carcinogenesis. Mutations introduced by UVR can lead to melanoma and nonmelanoma skin cancer, for example, basal cell carcinoma...

Oxidative damage is the principal cellular disturbance in the skin aging. Missense polymorphisms strengthen or weaken detoxification enzyme activity. Determination of deleterious functional effects of polymorphisms in detoxification genes (NQO1 and EPHX1) in skin aging was the overall purpose of conducting...

Skin aging is a complex, continuous, multifactorial process resulting from cumulative morphological and functional changes in the skin over time. This happens because of two processes: intrinsic and extrinsic skin aging. Intrinsic skin aging occurs naturally over time and reflects each person's genetic...