Anti-Aging medicineArchives
Neutralizing IL-22RA1 improves histologic and molecular alterations associated with atopic dermatitis pathogenesis
Anti-Aging medicine 1 min.
Disease of a subgroup of patients with atopic dermatitis (AD) does not show sufficient improvement with current systemic therapies, highlighting the heterogeneity of the chronic inflammatory skin disease and the need for novel treatments. In this study, we investigated the pathogenic contribution of...
Sympathetic nerve dysfunction exacerbates skin inflammation in atopic dermatitis
Anti-Aging medicine 1 min.
Atopic dermatitis (AD) is a chronic inflammatory skin disorder with severe itching, posing a great burden on both the physical and mental health of patients. AD is frequently complicated by sympathetic nervous system (SNS) dysfunction. We sought to explore the interplay between skin inflammation and...
Skin metabolism in obesity: A narrative review
Anti-Aging medicine 4 min.
Considered an epidemic and one of the main public health problems in the world, obesity is a complex multifactorial disease in which excess body fat triggers negative health effects. In adults, the World Health Organization defines ‘overweight’ as a body mass index (BMI) of 25.0–29.9...
Anti-ageing interventions for the treatment of cardiovascular disease
Anti-Aging medicine 1 min.
As the global demographic landscape continues to shift towards an aged population, so does the medical and socioeconomic burden of cardiovascular diseases. Indeed, ageing is one of, if not, the key risk factor for the development of cardiovascular diseases. However, there are currently no approved cardiovascular...
Exploring skin aging-associated genotypes; Moving toward delivery of precision medicine-based care more than beyond skin deep care: a genome-wide association study.
Anti-Aging medicine NaN min.
Oxidative damage is the principal cellular disturbance in the skin aging. Missense polymorphisms strengthen or weaken detoxification enzyme activity. Determination of deleterious functional effects of polymorphisms in detoxification genes (NQO1 and EPHX1) in skin aging was the overall purpose of conducting...
