Log in  First Connection?

Anti-Aging medicineArchives

Radiofrequency microneedling for skin rejuvenation of the periorbital region – a prospective, clinical study

 Published on 22/06/2026 |  Original article (Full-text)  | Lynhda Nguyen et al. | Journal of Cosmetic and Laser Therapy 2026; aop:10.1080/14764172.2026.2680304

Minimally invasive treatments such as fractional lasers are well-established options for addressing the aging skin in the periorbital region. Among energy-based devices, radiofrequency microneedling (RFMN) has emerged as a potential alternative. To evaluate the effectiveness and safety of RFMN for periorbital...

Design and evaluation of multi-target AGEs/ALEs inhibitors for potential application in skin anti-aging

 Published on 01/06/2026 |  Original article (Full-text)  | N. et al. | Future Medicinal Chemistry 2026; OnlineFirst(-): 1-7

The main causes of skin aging include both intrinsic and extrinsic factors such as oxidative stress triggered by reactive oxygen species (ROS), modification of collagen and elastin by reactive carbonyl species (RCS), UV exposure, lifestyle habits and environmental pollutants. Skin aging is the most visible...

Exploring skin aging-associated genotypes; Moving toward delivery of precision medicine-based care more than beyond skin deep care: a genome-wide association study.

 Published on 08/09/2025 |  PubMed  | Khashei Varnamkhasti Samire et al. | BMC geriatrics 2025 May; 25(1): 307

Oxidative damage is the principal cellular disturbance in the skin aging. Missense polymorphisms strengthen or weaken detoxification enzyme activity. Determination of deleterious functional effects of polymorphisms in detoxification genes (NQO1 and EPHX1) in skin aging was the overall purpose of conducting...

Pollution, a Relevant Exposome Factor in Skin Aging and the Role of Multi-benefit Photoprotection.

 Published on 01/09/2025 |  PubMed  | Santamaria J et al. | Actas dermo-sifiliograficas 2025 Jun; 116(6): 611-620

Skin aging is a complex, continuous, multifactorial process resulting from cumulative morphological and functional changes in the skin over time. This happens because of two processes: intrinsic and extrinsic skin aging. Intrinsic skin aging occurs naturally over time and reflects each person's genetic...