VirusArchives
Nucleocapsid protein enhances spike- and RBD-specific humoral and cellular immune responses in protein-based SARS-CoV-2 vaccine
Virus 16 min.
Coronaviruses (CoVs) are a diverse group of enveloped positive-sense single-stranded RNA viruses belonging to the subfamily Orthocoronavirinae, in the family Coronaviridae of the order Nidovirales. There are four endemic, human CoVs (HCoVs) circulating in the human population: HCoV-229E,...
Recombinant SARS-Cov-2 spike protein S1 subunit upregulates P2 × 7-NLRP3 leading to macrophage pyroptosis promoting acute lung injury
Virus 7 min.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a positive-sense single-stranded RNA virus with a 30 kb genome, causes multi-system manifestations of Coronavirus Disease 2019 (COVID-19) including cardiovascular, neurological, and respiratory complications through mechanisms involving myocardial...
Respiratory syncytial virus is associated with a higher disease burden than influenza and SARS-CoV-2 in adults with chronic lung disease: a multi-center cohort study
Virus 4 min.
Respiratory syncytial virus (RSV) is a common pathogen causing acute respiratory infections. A recent population-based cross-sectional study estimated that 123,000 to 193,000 RSV-associated hospitalizations occur annually among adults aged 18 years or older in the United States. RSV disproportionately...
Anti-SARS-CoV-2 Immunoglobulin G Antibody Titers in Contemporary Lots of Intravenous Immunoglobulin and Fresh Frozen Plasma Compared With COVID-19 Convalescent Plasma
Virus 1 min.
Given declining coronavirus disease 2019 convalescent plasma (CCP) collection and increasing scarcity, we compared anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) antibody titers between CCP, intravenous immunoglobulin, and fresh frozen plasma. Herein, we report...
