VirusArchives
Cardiorespiratory fitness and physical activity and risk of SARS-CoV-2 and COVID-19 hospitalization: the HUNT study
Virus 5 min.
Since its initial outbreak in March 2020, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and the coronavirus disease 2019 (COVID-19) pandemic has caused more than 776 million confirmed cases of infections and more than 7 million deaths worldwide (as of 25th of September 2024) [1, 2]....
Real-world comparative effectiveness of SARS-CoV-2 primary vaccination campaigns against SARS-CoV-2 infections: a federated observational study emulating a target trial in three nations
Virus 1 min.
To assess the impact of large-scale severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination campaigns in real-world settings across regions, we performed a reproducible cross-border comparison of the real-world effectiveness of primary vaccination in preventing SARS-CoV-2 infections...
Cell-free HPV DNA as a complementary biomarker to imaging in HPV-associated oropharyngeal squamous cell carcinoma: a narrative synthesis of key studies
Virus 1 min.
Human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma (OPSCC) represents a biologically distinct disease entity with superior prognosis compared with HPV-negative head and neck cancers. While imaging-based strategies, particularly those monitoring hypoxia, have emerged as...
Nucleocapsid protein enhances spike- and RBD-specific humoral and cellular immune responses in protein-based SARS-CoV-2 vaccine
Virus 16 min.
Coronaviruses (CoVs) are a diverse group of enveloped positive-sense single-stranded RNA viruses belonging to the subfamily Orthocoronavirinae, in the family Coronaviridae of the order Nidovirales. There are four endemic, human CoVs (HCoVs) circulating in the human population: HCoV-229E,...
Recombinant SARS-Cov-2 spike protein S1 subunit upregulates P2 × 7-NLRP3 leading to macrophage pyroptosis promoting acute lung injury
Virus 7 min.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a positive-sense single-stranded RNA virus with a 30 kb genome, causes multi-system manifestations of Coronavirus Disease 2019 (COVID-19) including cardiovascular, neurological, and respiratory complications through mechanisms involving myocardial...
