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Real-World Multicenter Study on the Effectiveness of Dolutegravir Plus Lamivudine in Treatment-Naive People Living with HIV with Baseline HIV-1 RNA > 500,000 Copies/mL
Virus
 1 min.

 Published on 16/07/2026 |  Original article (Full-text)  | Xue, Bichen et al. | Infectious diseases and therapy. Volume 15(8).

Dolutegravir (DTG) plus lamivudine (3TC) is one of the preferred treatment regimens for HIV, yet evidence remains limited for people living with HIV (PLWH) with high baseline viral load. This study aims to evaluate the effectiveness of DTG/3TC in treatment-naive PLWH with baseline viral load > 500,000...

Broadly neutralizing antibodies for HIV therapy in clinical trials: a systematic review
Virus
 1 min.

 Published on 09/07/2026 |  Original article (Full-text)  | Zhao, Jinfang et al. | Infectious Diseases of Poverty. Volume 15(1).

Lifelong daily antiretroviral therapy (ART) effectively suppresses human immunodeficiency virus type 1 (HIV-1) replication but does not eradicate the virus, underscoring the urgent need for long-acting antivirals and functional cure strategies. Broadly neutralizing antibodies (bNAbs) have emerged as...

Phytochemical and antiviral investigation of Cynanchum acutum L. extract and derived semi-synthetic analogs targeting SARS-CoV-2 main protease
Virus
 1 min.

 Published on 02/07/2026 |  Original article (Full-text)  | Abdelhameed, Reda F. A. et al. | Future Journal of Pharmaceutical Sciences. Volume 11(1).

The genus Cynanchum, family Apocynaceae is a group of climbing vines that have long been in folk medicine used as antitussives, analgesics, anticonvulsants, expectorants, diuretics, antifebriles, and tonics. Results: Cynanchum acutum crude extract was investigated to determine its chemical...

Underweight is associated with detectable viral load among adolescents with HIV in rural eastern Uganda: a retrospective cohort study
Virus
 1 min.

 Published on 25/06/2026 |  Original article (Full-text)  | Auca, Agnes et al. | Journal of Health, Population and Nutrition. Volume 45(1).

Detectable viral load (DVL) after ≥ 6 months of antiretroviral therapy (ART) and underweight are common among adolescents with HIV (AWH) but remain understudied. We assessed the association between underweight at ART initiation and DVL among AWH in rural eastern Uganda. Methods: We retrospectively...

Penile HPV prevalence among high-risk men in Sri Lanka: baseline insight for HPV prevention strategies in a lower-middle-income country
Virus
 1 min.

 Published on 18/06/2026 |  Original article (Full-text)  | Amarasena, W. D. J. K. et al. | Infectious Agents and Cancer. Volume 21(1).

Human Papillomavirus (HPV) infection is the most common sexually transmitted viral infection in the world. Persistent infection lasting more than two years, particularly with High-Risk (HR) HPV genotypes, can lead to malignant transformation. Estimating HPV prevalence among high-risk men in Sri Lanka...