VirusArchives
Longitudinal kinetics of the viral infection biomarker 3′-deoxy-3′,4′-didehydro-cytidine in SARS-CoV-2, influenza A virus and RSV human challenge models
Virus 6 min.
3′-deoxy-3′,4′-didehydro-cytidine (ddhC) is the free base of ddhC-triphosphate (ddhCTP), an antiviral small molecule encoded by the human genome1. We previously demonstrated that ddhC acts as an accurate biomarker for multiple viral infections by analysing sera from patients hospitalised...
Trends in HIV-related knowledge, behaviors and determinants of HIV testing among adolescent women aged 15–24 in Nigeria
Virus 6 min.
Young women in Nigeria continue to be disproportionately affected by the Human Immune deficiency Virus (HIV), with their vulnerability linked to multiple factors, including socioeconomic disadvantages, gender inequalities, and behavioral risks [1, 2–3]. Despite extensive global efforts to curb...
Two cases of Talaromyces marneffei tracheobronchial infection in HIV-negative patients
Virus 6 min.
Talaromyces marneffei (TM) initially named Penicillium marneffei, was isolated from the liver ofbamboo rats [1]. TM is a thermally dimorphic fungus endemic to northern Thailand, Vietnam, Myanmar, southern China, and northeastern India [2]. It is noteworthy that TM is the only known pathogenic...
The triage role of cytological DNA methylation in women with non-16/18, specifically genotyping high-risk HPV infection
Virus 5 min.
Persistent infection with high-risk human papillomavirus (hrHPV) is a major cause of invasive cervical cancer [1, 2]. The 2019 ASCCP Consensus Guidelines for Risk-Based Management recommend direct colposcopy for the primary screening of HPV-16/18 (+) and cytology for triage for other women with non-16/18...
