VirusArchives
SARS-CoV-2 spike triggers TLR7-dependent endolysosome dysfunction and senescence in human astrocytes
Virus 7 min.
COVID-19 patients continue to experience neurological and mental health-related symptoms ranging from cognitive impairments, such as brain fog, to mental health disorders, including anxiety and depression, beyond the acute phase of SARS-CoV-2 infection [1, 2, 3, 4, 5, 6, 7, 8, 9–10]. This is known...
Gut infection and dysbiosis are hallmarks of severe SARS-CoV-2 variants
Virus 6 min.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, first emerged in Wuhan, China, in December 2019 and rapidly spread worldwide, leading to over 7 million deaths to date.1 SARS-CoV-2 is an enveloped, single-stranded, positive-sense RNA virus2, whose entry into...
Comprehensive evaluation of NAT+/HBsAg– blood donors: confirmation strategies, serial testing outcomes, and S gene mutations associated with occult HBV infection
Virus 7 min.
Hepatitis B virus (HBV) infection remains a significant global health concern, with an estimated 296 million people chronically infected in 2019 [1]. HBV can be transmitted through transfusion, vertical transmission, sexual contact, and unsafe injections [2]. Therefore, rigorous blood screening for HBV...
Impact of SARS-CoV-2 on intrapartum cardiotocography: a retrospective cohort study
Virus 4 min.
Pregnant women were identified as a vulnerable group to the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since they have been prone to complications and severe disease due to other coronaviruses. The impact on the fetus of maternal infection seems to be limited to the consequences of placental...
Antibiotic overuse in a contemporary cohort of children hospitalized with influenza, RSV, or SARS-CoV-2: a retrospective cohort study
Virus 3 min.
The burden of pediatric hospitalizations for viral lower respiratory tract infections (LRTIs) is substantial. In the U.S., over 22,000 children have been hospitalized with COVID-19 since 2020, 12,000–46,000 children are hospitalized with influenza each year, and up to 80,000 children < 5...
