VirusArchives
Decline of HIV infection: legacy of tenofovir (A. Holý) and rilpivirine (P. Janssen)
Virus 1 min.
Among the wide variety of antivirals that have been developed for the treatment of human immunodeficiency virus (HIV) infections and acquired immunodeficiency syndrome (AIDS), two stand out: tenofovir and rilpivirine. The names unmistakenly associated with the discovery of these two compounds, are Antonín...
The potential roles of IgG glycosylation in the development of non-communicable comorbidities in people with HIV
Virus 1 min.
The introduction of effective antiretroviral therapy (ART) has transformed Human Immunodeficiency Virus (HIV) infection from a once-fatal diagnosis into a manageable chronic condition, with life expectancy in people with HIV approaching that of the general population. However, this extended lifespan...
Cardiorespiratory fitness and physical activity and risk of SARS-CoV-2 and COVID-19 hospitalization: the HUNT study
Virus 5 min.
Since its initial outbreak in March 2020, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and the coronavirus disease 2019 (COVID-19) pandemic has caused more than 776 million confirmed cases of infections and more than 7 million deaths worldwide (as of 25th of September 2024) [1, 2]....
Real-world comparative effectiveness of SARS-CoV-2 primary vaccination campaigns against SARS-CoV-2 infections: a federated observational study emulating a target trial in three nations
Virus 1 min.
To assess the impact of large-scale severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination campaigns in real-world settings across regions, we performed a reproducible cross-border comparison of the real-world effectiveness of primary vaccination in preventing SARS-CoV-2 infections...
Cell-free HPV DNA as a complementary biomarker to imaging in HPV-associated oropharyngeal squamous cell carcinoma: a narrative synthesis of key studies
Virus 1 min.
Human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma (OPSCC) represents a biologically distinct disease entity with superior prognosis compared with HPV-negative head and neck cancers. While imaging-based strategies, particularly those monitoring hypoxia, have emerged as...
