
Abacavir (ABC), a guanosine analogue that inhibits reverse transcriptase, is presently used as a first-line treatment for children living with HIV (CLHIV) with a haemoglobin level below 9 g/dl by the National AIDS Control Organization (NACO) in India and it is also suggested as an alternative initial...

Since the identification of human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) in The 1980s, The epidemic has remained a major public-health challenge. In 2023, an estimated 39.6 million people were living with HIV worldwide, with 1.3 million new infections and...

Liver cancer poses a significant threat to global public health security, presenting substantial challenges in clinical prevention and management. According to the latest World Health Organization statistics, approximately 760,000 deaths annually are attributed to liver cancer worldwide [1]. Hepatocellular...

Multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR-TB) represent a critical antimicrobial resistance threat, significantly compromising treatment efficacy and overwhelming healthcare systems in endemic regions [1, 2]. Compared to drug-susceptible tuberculosis (TB) (more than 85%...