VirusArchives
Characteristics of extracellular vesicle-derived lncRNAs during the progression of HBV-related hepatocellular carcinoma
Virus 7 min.
Liver cancer poses a significant threat to global public health security, presenting substantial challenges in clinical prevention and management. According to the latest World Health Organization statistics, approximately 760,000 deaths annually are attributed to liver cancer worldwide [1]. Hepatocellular...
Global burden of HIV and drug-resistant tuberculosis co-infection and its attributable risk factors, 1990 to 2021, with projections to 2031
Virus 4 min.
Multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR-TB) represent a critical antimicrobial resistance threat, significantly compromising treatment efficacy and overwhelming healthcare systems in endemic regions [1, 2]. Compared to drug-susceptible tuberculosis (TB) (more than 85%...
SARS-CoV-2 spike triggers TLR7-dependent endolysosome dysfunction and senescence in human astrocytes
Virus 7 min.
COVID-19 patients continue to experience neurological and mental health-related symptoms ranging from cognitive impairments, such as brain fog, to mental health disorders, including anxiety and depression, beyond the acute phase of SARS-CoV-2 infection [1, 2, 3, 4, 5, 6, 7, 8, 9–10]. This is known...
Gut infection and dysbiosis are hallmarks of severe SARS-CoV-2 variants
Virus 6 min.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, first emerged in Wuhan, China, in December 2019 and rapidly spread worldwide, leading to over 7 million deaths to date.1 SARS-CoV-2 is an enveloped, single-stranded, positive-sense RNA virus2, whose entry into...
