Intestinal DiseasesArchives
Inverted day-night feeding during pregnancy affects the brain health of both maternal and fetal brains through increasing inflammation levels associated with dysbiosis of the gut microbiome in rats
Intestinal Diseases 10 min.
Time-restricted feeding, a form of intermittent fasting, involves fasting for more than 12 h daily and represents an emerging behavioral nutritional intervention that can assist in treating neuropsychiatric disorders [1]. However, there is ongoing debate regarding whether this 24-h cyclical dietary...
Association between gestational diabetes mellitus, maternal health and diet, and gut microbiota in mother-infant dyads
Intestinal Diseases 7 min.
Gestational diabetes mellitus (GDM) is the onset of glucose intolerance first occurring during pregnancy [1]. It is well established that GDM predisposes mothers and their offspring to short- and long-term health consequences [2, 3, 4–5]. For instance, mothers who develop GDM, along with their...
Novel insights into immune-gut microbiota interactions in colorectal cancer: a Mendelian randomization study
Intestinal Diseases 5 min.
Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive system, ranking third in incidence and second in cancer-related mortality worldwide, posing a significant public health burden [1]. The development of CRC is influenced by multiple factors. These include genetic predisposition...
Gut microbiota affects PD-L1 therapy and its mechanism in melanoma
Intestinal Diseases 6 min.
Melanoma is a prevalent and significant cancer type [1]. Historically, the five-year survival rate for advanced melanoma was only 10%. However, the advent of immune checkpoint inhibitors has revolutionized cancer treatment, leading to notable success in managing advanced malignancies. A prominent example...
Clostridioides difficile concentration-dependant alterations in gut microbiota of asymptomatic infants
Intestinal Diseases 3 min.
Prevalence of asymptomatic colonization with Clostridioides difficile in infants is estimated at approximately 40% [1], however varies considerably according to geographic location, age, breastfeeding, and underlying medical conditions [2, 3]. Colonization rates with both toxigenic and non-toxigenic...
