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[18F]AlF-NOTA-PCP2 PET/CT to Assess PD-L1 Status in Head and Neck Cancer: Head-to-Head Comparison With [18F]FDG PET/CT.

 Published on 02/06/2026 |  Original article (Full-text)  | Wang, Yong MD, et al. | Clinical Nuclear Medicine. Volume 51(1).

While PD-L1 expression heterogeneity limits the predictive value of localized biopsies, molecular imaging offers a dynamic alternative. We developed [18F]AlF-NOTA-PCP2, a hydrophilic PD-L1-targeted peptide tracer, and first evaluated its clinical utility in head and neck (HNC) cancer through a head-to-head...

Interpretable deep learning for multicenter gastric cancer T staging from CT images

 Published on 26/05/2026 |  Original article (Full-text)  | Zheng Guoliang et al. | npj Digital Medicine 2026; 9(1): 2

Gastric cancer is a major global health burden and remains among the top causes of cancer-related deaths worldwide1. Despite advances, many patients still present with advanced disease due to limited early detection, complicating treatment2. Accurate preoperative T staging guides decisions from endoscopic...

An integrated radiomics and deep learning model on multisequence MRI for preoperative prediction of lymphovascular space invasion in endometrial cancer

 Published on 19/05/2026 |  Original article (Full-text)  | Luo Hong-Jian et al. | BMC Medical Imaging 2025; 26(1): 22

Endometrial cancer (EC) is the second most common gynecologic malignancy in China, with an increasing incidence [1]. Contemporary treatment strategies increasingly emphasize personalized care. The 2021 joint guidelines from the European Society of Gynecological Oncology (ESGO), the European Society for...

Development and validation of a CT-radiomics model for the diagnosis of lung cancer associated with cystic airspaces: a multicenter study

 Published on 12/05/2026 |  Original article (Full-text)  | Ai Jiangshan et al. | BMC Cancer 2025; 26(1): 78

Lung cancer associated with cystic airspaces (LCCA) is a relatively uncommon form of lung malignancy. The Fleischner Society initially defined lung cystic airspace in 1996 as an enlarged peripheral air-containing unit surrounded by a variable thickness wall [1]. In the early stages, cystic airspaces...

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 Published on 14/11/2024 |  Original article (Full-text)  |