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Exploring the role of tumor to background parenchymal ratio of the [18F]FLT PET/CT measures in determining response to neoadjuvant chemotherapy in breast cancer: a multicenter study

 Published on 08/07/2025 |  Original article (Full-text)  | Mohebbi Alisa et al. | BMC Cancer 2025; 25(1): 1138

Breast cancer, accounting for 23% of cases of all cancer diagnoses worldwide, represents the most prevalent cancer diagnosed in females and the fifth leading cause of cancer-related death among this population [1, 2]. Locally advanced breast cancer (LABC) is commonly defined as tumors inoperable at presentation...

CT delta-radiomics predicts the risks of blood transfusion and massive bleeding during spinal tumor surgery

 Published on 01/07/2025 |  Original article (Full-text)  | Liu Suwei et al. | Cancer imaging 2025; 25(1): 79

Spinal tumors often require surgical resection, especially when there is nerve compression, spinal instability, and intractable pain [1, 2]. However, spinal tumor surgeries are frequently complicated by intraoperative bleeding, due to the spine’s complex anatomy and rich vascular supply [3, 4]. To...

An update on the role of endobronchial ultrasound-guided transbronchial needle aspiration in lung cancer management

 Published on 24/06/2025 |  Original article (Full-text)  | Takahiro Nakajima et al. | Expert Review of Respiratory Medicine 2025; 19(5): 423-34

Accurate diagnosis and staging are essential for optimizing lung cancer management. The 9th edition of the TNM classification emphasizes distinguishing between single-station and multi-station N2 disease, highlighting the necessity of comprehensive mediastinal node assessment for clinical staging. Endobronchial...

Development of an ultrasound-mediated nano-sized drug-delivery system for cancer treatment: from theory to experiment

 Published on 17/06/2025 |  Original article (Full-text)  | Farshad Moradi Kashkooli * et al. | Nanomedicine 2024; 19(13): 1167-89

To establish a methodology for understanding how ultrasound (US) induces drug release from nano-sized drug-delivery systems (NSDDSs) and enhances drug penetration and uptake in tumors. This aims to advance cancer treatment strategies. Materials & methods: We developed...

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 Published on 14/11/2024 |  Original article (Full-text)  |