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Machine learning-DeepSurv prediction model integrating mpMRI radiomics and genomic biomarkers for BCR-free survival and tumor response in prostate radiotherapy

 Published on 24/03/2026 |  Original article (Full-text)  | Hossein Taheri et al. | Journal of Radiation Research. Volume 67(1).

The purpose of this study was to design a radiogenomics machine learning-DeepSurv model for biochemical recurrence-free (BCR-free) survival and treatment response (TR) prediction for radiotherapy (RT) of prostate cancer (PCa). In this study, radiomic features were extracted from pre and post treatment...

Ultrasound for predicting pathological response to neoadjuvant chemotherapy in patients with breast cancer: a systematic review and meta-analysis

 Published on 17/03/2026 |  Original article (Full-text)  | Shi Qing Feng et al. | BMC Cancer 2026; 26(1): 219

Breast cancer (BC) is the second most common malignant neoplasm globally, and it ranks fifth as a cause of death [1]. Neoadjuvant chemotherapy (NAC) can reduce patient’s primary tumor burden and the extent of nodal involvement, which may increase the likelihood of breast-conserving surgery and...

A SHAP-interpretable XGBoost model: MRI-based intratumoral perfusion heterogeneity predicts HER2-zero, -low, and -positive ternary expression status in breast cancer

 Published on 10/03/2026 |  Original article (Full-text)  | Wang Shuxing et al. | Cancer imaging 2026; 26(1): 35

Breast cancer is a prevalent malignant tumor among women worldwide, accounting for 11.6% of new cases annually [1]. Human epidermal growth factor receptor 2 (HER-2) is a significant factor influencing the prognosis of patients with breast cancer. It is a crucial gene target for breast cancer treatment...

Integrated primary tumor and all metastatic lymph nodes radiomics from 18 F-FDG PET/CT for precise M1 subclassification in nasopharyngeal carcinoma

 Published on 03/03/2026 |  Original article (Full-text)  | Zhang Yun et al. | BMC Cancer 2026; 26(1): 251

Nasopharyngeal carcinoma (NPC) shows a markedly higher incidence in endemic regions––especially China and Southeast Asia––but remains relatively rare in Western populations [1, 2]. Its global incidence and mortality are projected to increase substantially by 2040, particularly...

Interpretable machine learning using CT radiomics predicts pathological upgrading after secondary resection in non-muscle-invasive bladder cancer

 Published on 24/02/2026 |  Original article (Full-text)  | Rao Xue Peng et al. | BMC Cancer 2026; 26(1): 278

Bladder cancer is a common malignant tumor of the urinary system worldwide, with more than 600,000 new cases and over 200,000 deaths annually. Its incidence and mortality rates rank 10th and 13th among all malignant tumors, respectively [1, 2]. Pathologically, bladder cancer is primarily classified into...

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 Published on 14/11/2024 |  Original article (Full-text)  |