
While PD-L1 expression heterogeneity limits the predictive value of localized biopsies, molecular imaging offers a dynamic alternative. We developed [18F]AlF-NOTA-PCP2, a hydrophilic PD-L1-targeted peptide tracer, and first evaluated its clinical utility in head and neck (HNC) cancer through a head-to-head...

Gastric cancer is a major global health burden and remains among the top causes of cancer-related deaths worldwide1. Despite advances, many patients still present with advanced disease due to limited early detection, complicating treatment2. Accurate preoperative T staging guides decisions from endoscopic...

Endometrial cancer (EC) is the second most common gynecologic malignancy in China, with an increasing incidence [1]. Contemporary treatment strategies increasingly emphasize personalized care. The 2021 joint guidelines from the European Society of Gynecological Oncology (ESGO), the European Society for...

Lung cancer associated with cystic airspaces (LCCA) is a relatively uncommon form of lung malignancy. The Fleischner Society initially defined lung cystic airspace in 1996 as an enlarged peripheral air-containing unit surrounded by a variable thickness wall [1]. In the early stages, cystic airspaces...