
Pain assessment in animal models is challenging, as behavioral tests often lack sensitivity. Particularly under analgesia, it is unclear whether pain occurs without medication. Imaging of pain-associated pathways, such as σ1 receptor (σ1R) expression, offers a promising approach to better...

The expanding use of medical diagnostics and radiotherapy has increased public exposure to low dose ionizing radiation (LDIR). A more clinically pressing concern, however, is the unintended irradiation of normal tissues adjacent to the radiotherapy target. Notably, the biological effects of lower cumulative...

Despite increasing interest in endoscopic and histological remission as a treatment target in ulcerative colitis (UC), the accuracy of endoscopic and histological findings in the left colon and/or rectum to detect pancolonic remission is poorly known. We aimed to compare the diagnostic accuracy of rectosigmoidoscopy...

Complete duodenal disruption from blunt abdominal trauma is rare but life-threatening, especially when involving the second and third portions near the ampulla of Vater, which are essential for bile and pancreatic drainage. Such injuries predispose to high-output fistulas, nutritional depletion, and...

Acute pancreatitis is a disease of varying severity with a clinical spectrum ranging from mild, self-limiting disease to severe necrotizing pancreatitis associated with significant morbidity and mortality [1]. Approximately 10-20% of patients with acute pancreatitis develop pancreatic and peripancreatic...