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Machine learning-based differentiation of benign and malignant adrenal lesions using 18F-FDG PET/CT: a two-stage classification and SHAP interpretation study

 Published on 14/11/2025 |  Original article (Full-text)  | Wang Yun et al. | BMC Cancer 2025; 25(1): 1724

Adrenal lesions are frequently encountered in oncology imaging, particularly in patients with known malignancies. Approximately 50% of adrenal masses identified in individuals with extra-adrenal primary malignancies represent metastases, while benign adrenal lesions may coexist in patients with malignancy,...

A contrast‑enhanced CT histogram‑driven nomogram for predicting post‑radiotherapy liver regeneration in hepatocellular carcinoma

 Published on 07/11/2025 |  Original article (Full-text)  | Liu Bo et al. | Radiation Oncology 2025; 20(1): 159

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide [1]. Radical hepatic resection is the standard curative treatment for early-stage HCC; however, many patients present with high-risk pathological features such as narrow surgical margins (< 1 cm) or microvascular...

Assessment of tertiary lymphoid structures via 18F-FDG PET/CT scan in patients with pancreatic adenocarcinoma

 Published on 01/11/2025 |  Original article (Full-text)  | Yan Yu et al. | Cancer Immunology, Immunotherapy 2025; 74(11): 345

Pancreatic adenocarcinoma (PAAD) is one of the most common malignancies and ranks as the sixth leading cause of cancer-related mortality [1]. Most PAAD patients are diagnosed at an advanced stage owing to the absence of timely diagnosis and typical symptoms at an early stage, resulting in an overall...

Head-to-head comparison of [18F] fluorodeoxyglucose PET/CT and [68Ga]Ga-prostate specific membrane antigen-11 PET/CT in radioactive iodine refractory differentiated thyroid cancer.

 Published on 24/10/2025 |  Original article (Full-text)  | Kibar, Alia et al. | Nuclear Medicine Communications. Volume 46(11).

Radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC) is associated with challenges in both imaging and treatment due to resistance to I-131. The aim of this study is to compare the lesion detection rates of [18F] fluorodeoxyglucose (FDG) PET/computed tomography [CT] and [68Ga]Ga-prostate...