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Diagnostic value of IVIM and DCE-MRI parameters for differentiating benign from malignant bone tumors and their correlations with Ki-67 expression

 Published on 12/02/2026 |  Original article (Full-text)  | Lin Mingui et al. | BMC Cancer 2025; 26(1): 195

Bone tumors are complex histological types with aggressive malignancies and high metastatic rates, making accurate differentiation between benign and malignant lesions crucial for treatment decisions [1]. The current National Comprehensive Cancer Network (NCCN) guidelines recommend imaging modalities,...

Transformer-based and CNN-based models for clinically effective 2D and 3D pelvic bone segmentation in CT imaging

 Published on 05/02/2026 |  Original article (Full-text)  | Nesheli Shabnam Jafarpoor et al. | BMC Musculoskeletal Disorders 2025; 27(1): 68

Advancements in deep learning (DL) have revolutionized medical image analysis, particularly in automating and enhancing the precision of diagnostic tasks [1]. Among these, the segmentation of pelvic and hip structures stands out as both critically important and technically challenging [2, 3–4]....

Discrepancy between X-ray and CT assessment in the Mirels score for long bone metastasis

 Published on 29/01/2026 |  Original article (Full-text)  | Kimura Tomohiro et al. | BMC Musculoskeletal Disorders 2025; 27(1): 24

The Mirels score is a prediction system proposed by Mirels in 1989 to evaluate the risk of pathological fracture of long bone metastasis within six months and comprises four factors: pain, (anatomical) site, size, and lesion (radiographic appearance). Each factor is rated from one to three points, and...

Multiple brown tumors caused by parathyroid adenoma identified by 18F-FDG PET/CT in a patient with thalassemia: a case report

 Published on 22/01/2026 |  Original article (Full-text)  | Liu Xiu-Feng et al. | BMC Endocrine Disorders 2025; 26(1): 12

The parathyroid tumor secretes excessive amounts of parathyroid hormone, leading to hypercalcemia and associated complications such as osteoporosis, bone fractures, and brown tumors [1]. Brown tumors are rare skeletal lesions characterized by their distinctive brown color, which results from increased...

MRI-based habitat analysis for differentiating benign and malignant vertebral compression fractures

 Published on 15/01/2026 |  Original article (Full-text)  | Liu Xiaoshan et al. | BMC Medical Imaging 2025; 26(1): 5

Vertebral compression fractures (VCFs) are prevalent conditions within the skeletal system encountered in clinical practice. The increasing trend in their incidence is notably associated with the intensification of population aging [1]. VCFs significantly impair patients’ quality of life by inducing...