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Clinical and biochemical amenorrhea in premenopausal patients with breast cancer treated with chemotherapy - a prospective cohort study
Menopause
 6 min.

 Published on 02/05/2025 |  Original article (Full-text)  | Raveendran Ciniraj et al. | BMC Cancer 2025; 25(1): 752

Recent cancer facts show that Breast cancer is the leading cause of cancer in women, constituting 23.8% of new cases of cancer and a leading cause of cancer-related mortality [1]. Global statistics show that the prevalence and incidence of breast cancer among young women are increasing at an alarming...

The hypothalamic estrogen receptor α pathway is involved in high-intensity interval training-induced visceral fat loss in premenopausal rats
Menopause
 10 min.

 Published on 25/04/2025 |  Original article (Full-text)  | Wang Juanjuan et al. | Lipids in Health and Disease 2025; 24(1): 118

Obesity has become a serious threat to human health. For decades, it has been established that central obesity, rather than total body fat, is a significant risk factor for adverse health outcomes. The excessive accumulation of visceral adipose tissue (VAT) constitutes a significant component of metabolic...

The effects of transdermal estrogens combined with Medroxyprogesterone Acetate on cardiovascular disease risk factors in postmenopausal women: a meta-analysis of randomized controlled trials
Menopause
 4 min.

 Published on 18/04/2025 |  Original article (Full-text)  | Zhou Fan et al. | Diabetology & Metabolic Syndrome 2025; 17(1): 111

Cardiovascular disease (CVD) is the leading cause of mortality worldwide, with one-third of global deaths attributed to it [1, 2]. The risk of CVD increases with menopause, as postmenopausal women experience a reduction in cardioprotective effects [3]. Globally, the prevalence of CVD risk rate inclined...

Optimal extension time after initial endocrine therapy for postmenopausal hormone receptor-positive early-stage breast cancer: a systematic review and meta-analysis
Menopause
 4 min.

 Published on 11/04/2025 |  Original article (Full-text)  | Ying Zhang et al. | BMC Women's Health 2025; 25(1): 154

Breast cancer is the most prevalent form of cancer among females, comprising around 25% of all female malignancies and surpassing lung cancer in incidence [1, 2]. About 60%-70% of all breast cancers are hormone receptor-positive (HR-positive) [3], is treated with endocrine therapy (ET) as a key component,...