Bipolar DisordersArchives
Self-assessment and rest-activity rhythm monitoring for effective bipolar disorder management: a longitudinal actigraphy study
Bipolar Disorders 7 min.
Bipolar disorder (BD) affects approximately 1–2% of the world population, profoundly impacting the quality of life, functioning, and overall health [1]. Increasing evidence strongly suggests a pivotal role for circadian rhythms in the onset, course, and management of BD. Sleep and circadian disruption...
Sex-specific associations of episode type in bipolar I disorder with neuro-metabolic lateralization of the cortico-striatal-cerebellar (CSC) circuit
Bipolar Disorders 7 min.
Bipolar Disorder (BD) is a severe and recurrent psychiatric disorder characterized by alternating episodes of mania, hypomania, and depression, frequently accompanied by cognitive impairments and significant functional disability [1, 2]. Its clinical manifestations show significant sex heterogeneity:...
Bipolar and major depressive disorders: associations with serum zonulin levels and rs2070937 polymorphism
Bipolar Disorders 5 min.
Mood disorders are a major global cause of disability, morbidity, and mortality [1]. Among them, major depressive disorder (MDD) and bipolar disorder (BD) are the most prevalent, characterized by emotional and cognitive impairments that substantially limit daily functioning and reduce quality of life...
Differential microRNA profiling of blood L1CAM and bulk extracellular vesicles in bipolar disorder
Bipolar Disorders 1 min.
This preliminary study aimed to identify microRNA (miRNA) signatures associated with bipolar disorder (BD) by profiling blood-derived extracellular vesicles (EVs) of both putative neuronal origin and from all sources. In two parallel studies of individuals with BD and controls (CON), we characterized...
