
Bipolar II disorder (BD II) is a chronic and severe psychiatric condition characterized by recurrent major depressive episodes alternating with hypomanic episodes. A nationwide epidemiological study [1] reported a lifetime prevalence of 0.09% for bipolar I disorder and 0.04% for bipolar II disorder...

Psychiatric diagnoses have historically relied on on empirical symptom patterns, yet the consistency of bipolar disorder (BD) diagnosis continues to confront substantial challenges of inaccurate treatment and adverse patient outcomes [1]. Especially, the diagnosis and clinical differentiation of BD and...

Bipolar disorder (BD) is a severe and disabling psychiatric disorder characterized by alternating episodes of mania and depression [1]. The global prevalence of BD varies between 1 And 2% [2], leading to a significant economic burden on both individuals and society [3]. Evidence suggests that seasonal...

Cases have been recently reported in Japan of middle-aged and older individuals who have a sudden onset of photophobia and mixed negative electroretinograms (ERGs). The amplitude of the a-wave was normal but the rod, cone, and flicker responses were markedly reduced. Night blindness was a rare complaint...