Bipolar DisordersArchives
The Swedish bipolar collection (SWEBIC)
Bipolar Disorders 6 min.
Bipolar disorder is characterised by episodes of mania and depression interspersed with periods of remission. The condition is highly heritable (~ 60–85%) (Lichtenstein, et al. 2009; McGuffin, et al. 2003) and first-degree relatives to index cases suffer eight times higher risk of developing bipolar...
Baseline serum testosterone and differential efficacy of bipolar androgen therapy and enzalutamide in the randomized TRANSFORMER trial
Bipolar Disorders 2 min.
Bipolar androgen therapy (BAT) is the paradoxical approach whereby mCRPC patients alternate between supraphysiologic and near-castrate serum testosterone levels, through intramuscular administration of testosterone cypionate 400 mg given every 28 days together with ongoing androgen suppression....
Cognitive and affective theory-of-mind impairment in people with early-stage bipolar disorder
Bipolar Disorders 5 min.
Theory of Mind (ToM) is the capacity to describe mental states to oneself and others and the ability to respond accordingly [1]. It comprises two domains: cognitive or social-cognitive ToM - the ability to make inferences about another’s thoughts and intentions [2, 3–4], and affective or...
Short-term and long-term effects of Muslim fasting on lithium pharmacokinetics and renal function in bipolar disorder: a prospective observational study
Bipolar Disorders 4 min.
Lithium has been a cornerstone of mood stabilization, remaining a primary treatment option for bipolar I disorder since its approval by the U.S. FDA. Despite its established role in managing this condition, lithium treatment demands meticulous monitoring and awareness of factors that can affect its behavior...
