Bipolar DisordersArchives
An evaluation of aripiprazole long-acting injectable monthly and bimonthly in the maintenance treatment of bipolar I disorder
Bipolar Disorders 1 min.
Bipolar disorder (BD) is a chronic and severe mental disorder with a high risk for recurrence, requiring long-term mood stabilization treatment approaches. The hazards of recurrence in BD include illness progression, decreasing treatment response, chronicity, comorbidity, suicidality, increased health...
Efficacy and safety of pharmacological and non-invasive brain stimulation for adolescent bipolar depression: a systematic review and network meta-analysis
Bipolar Disorders 1 min.
This network meta-analysis evaluates the efficacy and safety of pharmacological and physical treatments for depressive episodes in adolescents with bipolar disorder (BD), incorporating evidence from six randomized controlled trials (RCTs), total N = 879. Due to the absence of shared comparators,...
Sex differences in prevalence and clinical correlates for psychotic symptoms in first-episode drug-naďve patients with bipolar disorder: a cross-sectional study
Bipolar Disorders 1 min.
Psychotic symptoms, which affect a significant proportion of patients with bipolar disorder (BD), are associated with adverse prognostic outcomes. Currently, sex-specific patterns of psychotic symptoms remain inadequately characterized in BD. This study seeks to investigate sex-based differences in psychotic...
The relationship between Urokinase-Plasminogen Activator Receptor (UPAR) and bipolar disorder: a case-control study, Egypt
Bipolar Disorders 1 min.
Bipolar disorder (BD)- a leading cause of disability in young adults- lacks reliable biomarkers. This case-control study investigates soluble urokinase plasminogen activator receptor (suPAR), a protein bridging inflammation and neural repair, as a novel biomarker candidate among Egyptian patients with...
