
Bipolar depression with acute suicidal ideation and behavior (ASIB) is a life- threatening manifestation of bipolar disorder (BD), with a suicide risk higher than that in other psychiatric disorders and the general population. Rapid and effective interventions are critical, as traditional therapies are...

It is difficult to model bipolar disorder in animals because the illness has opposed behavioral expressions and a multitude of associated pathophysiologic anomalies. The authors undertook a focused narrative review. The authors searched PubMed for all animal models of mania or bipolar disorder but focused...

Bipolar Disorder (BD) is a severe mental illness (SMI) affecting approximately 2–3% of the general population and is associated with a significantly reduced life expectancy, often by as much as 20 years (Faedda et al. 2015). Despite its substantial impact, a clearly defined at-risk mental...

Substance-induced psychosis (SIP) is characterized by the occurrence of delusions and/or hallucinations following the consumption or withdrawal of a recently ingested psychoactive substance [1]. It is distinguished from organic psychoses, such as those classified under the schizophrenia spectrum disorder...

Bipolar disorder (BD) is a serious and persistent mood disorder that significantly impairs patients’ social functioning and quality of life [29]. It ranks among the leading causes of disability worldwide [35]. According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition...