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Bipolar DisordersArchives

Efficacy and safety of pharmacological and non-invasive brain stimulation for adolescent bipolar depression: a systematic review and network meta-analysis
Bipolar Disorders
 1 min.

 Published on 14/07/2026 |  Original article (Full-text)  | Wang, Lifei et al. | International Journal of Bipolar Disorders. Volume 14(1).

This network meta-analysis evaluates the efficacy and safety of pharmacological and physical treatments for depressive episodes in adolescents with bipolar disorder (BD), incorporating evidence from six randomized controlled trials (RCTs), total N = 879. Due to the absence of shared comparators,...

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Sex differences in prevalence and clinical correlates for psychotic symptoms in first-episode drug-naïve patients with bipolar disorder: a cross-sectional study
Bipolar Disorders
 1 min.

 Published on 07/07/2026 |  Original article (Full-text)  | Chen, Yehong et al. | Annals of General Psychiatry. Volume 25(1).

Psychotic symptoms, which affect a significant proportion of patients with bipolar disorder (BD), are associated with adverse prognostic outcomes. Currently, sex-specific patterns of psychotic symptoms remain inadequately characterized in BD. This study seeks to investigate sex-based differences in psychotic...

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The relationship between Urokinase-Plasminogen Activator Receptor (UPAR) and bipolar disorder: a case-control study, Egypt
Bipolar Disorders
 1 min.

 Published on 30/06/2026 |  Original article (Full-text)  | Youssef, Usama Mahmoud et al. | Middle East Current Psychiatry. Volume 33(1).

Bipolar disorder (BD)- a leading cause of disability in young adults- lacks reliable biomarkers. This case-control study investigates soluble urokinase plasminogen activator receptor (suPAR), a protein bridging inflammation and neural repair, as a novel biomarker candidate among Egyptian patients with...

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Somatic morbidity in bipolar disorders
Bipolar Disorders
 1 min.

 Published on 23/06/2026 |  Original article (Full-text)  | Takami, Christine et al. | International Journal of Bipolar Disorders. Volume 14(1).

This Swedish nationwide cohort study used large-scale data to investigate the associations between bipolar disorder and somatic disorders and whether these risks differ by subtype, sex, or exposure to compulsory care. Methods: 61,071 individuals diagnosed with bipolar disorder in inpatient (from 1973)...

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