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Proteomic and lipidomic analysis of low-density lipoprotein identifies potential biomarkers of early estrogen receptor-positive breast cancer
Breast
 5 min.

 Published on 06/05/2025 |  Original article (Full-text)  | Abu Mohsen Yamama et al. | Cancer & Metabolism 2025; 13(1): 20

Breast cancer (BC) is the most prevalent and fatal cancer affecting women worldwide [1], however we still lack sufficient tools to detect and halt its progression at an early stage. Approximately 80% of BC cases are hormone-responsive BC, characterized by estrogen receptor (ER) expression in BC cells....

Association between triglyceride-glucose related indicators, genetic risk, and incident breast cancer among postmenopausal women in UK Biobank
Breast
 6 min.

 Published on 29/04/2025 |  Original article (Full-text)  | Li Zhen et al. | BMC Cancer 2025; 25(1): 780

Breast cancer stands as the most prevalent form of cancer among women and the primary cause of cancer-related mortality in women, with its burden anticipated to rise consistently [1, 2]. Notably, metabolic risks, such as an elevated body mass index (BMI) and heightened fasting glucose levels, are significant...

Early detection of triple-negative breast cancer: evidence of a favourable prognostic impact in a comparative analysis of screen-detected versus symptomatic cases
Breast
 5 min.

 Published on 22/04/2025 |  Original article (Full-text)  | Castellano Isabella et al. | BMC Cancer 2025; 25(1): 730

Breast cancer (BC) is the most prevalent cancer globally, accounting for 11.7% of all cancer cases, with approximately 2.3 million new cases and 685,000 deaths reported worldwide in 2020 [1]. In Italy BC is the most frequently diagnosed cancer among women, with an estimated 55,900 new cases in 2023...

Validation of in vivo dose using EPID combined with fan-beam CT guidance in post-breast-conserving radiotherapy for early-stage breast cancer
Breast
 8 min.

 Published on 15/04/2025 |  Original article (Full-text)  | Zhu Wanli et al. | BMC Cancer 2025; 25(1): 667

Radiotherapy following breast-conserving surgery for early-stage breast cancer may enhance locoregional control, diminish the risk of tumor recurrence, and extend survival [1]. However, the potential for inadequate dosing to the targeted breast area and increased doses of normal tissues is a consequence...