
Breast cancer is the most prevalent malignancy and a leading cause of cancer-related mortality among women worldwide [1]. The human epidermal growth factor receptor 2 (HER2) is a critical biomarker and therapeutic target in breast cancer, influencing both treatment response and disease progression [2,...

Breast cancer has emerged as the most prevalent malignant neoplasm globally and represents the second leading cause of cancer-related mortality among women worldwide [1]. Given the pronounced heterogeneity characteristic of breast cancer, the identification of optimal therapeutic strategies tailored...

Radiomics is an emerging field in medical imaging that leverages advanced computational algorithms to extract textural characteristics from medical images. It promises to transform breast cancer management by providing more accurate, reproducible, and noninvasive tools for clinicians, ultimately improving...

Recent studies indicate that early changes on 2-deoxy-2-[18F]fluoro-D-glucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT) predict response to human epidermal growth factor receptor 2 (HER2)-directed therapy. EA1211/DIRECT is a multicenter, single-arm, primary imaging phase 2 study enrolling...