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Prognostic value of baseline FDG PET/CT in HER2-positive metastatic breast cancer treated with first-line trastuzumab, pertuzumab, and docetaxel

 Published on 24/04/2026 |  Original article (Full-text)  | Kubeczko Marcin et al. | Breast Cancer Research 2025; 28(1): 32

Over the past two decades, HER2-targeted therapy has dramatically improved outcomes in advanced HER2-positive breast cancer [1, 2–3]. Trastuzumab combined with chemotherapy was the initial backbone, and the landmark phase III CLEOPATRA trial established that adding pertuzumab to first-line trastuzumab...

Adaptive ensemble learning for prostate cancer classification on multi-modal MRI: reducing unnecessary biopsies

 Published on 17/04/2026 |  Original article (Full-text)  | Aymaz Samet et al. | BMC Medical Imaging 2026; 26(1): 76

Accurate diagnosis of prostate cancer using MRI remains challenging due to variable imaging presentations and differences in reader experience [1, 2]. Radiologists often struggle to maintain interpretation consistency, leading to substantial interobserver variability and suboptimal specificity in lesion...

Incidence and Resource Burden for the Management of CT-detected Ground-Glass Opacities at a Tertiary Lung Cancer Service in the United Kingdom

 Published on 10/04/2026 |  Original article (Full-text)  | Abdullah AlShammari et al. | European journal of cardio-thoracic surgery. Volume 67(7).

The increased use of CT for lung cancer screening has significantly raised awareness of pure ground-glass opacity (pGGO) lesions. GGOs pose diagnostic challenges, ranging from benign findings to invasive adenocarcinomas. We aim to evaluate the incidence of pGGOs identified on CT at a tertiary UK lung...

Prostate cancer with incidental thoracic splenosis: a diagnostic challenge unveiled by 18 F-PSMA PET/CT imaging

 Published on 03/04/2026 |  Original article (Full-text)  | Vlaes Branko et al. | Journal of Cardiothoracic Surgery 2025; 21(1): 85

Thoracic splenosis is a rare, acquired anomaly in which splenic cells are autotransplanted into the thoracic cavity after thoracoabdominal trauma or surgery. Overall, splenosis is relatively common, occurring in approximately 58% to 65% of patients after splenic trauma. In these cases, the splenic tissue...

Multiparametric MRI-based habitat analysis integrating deep learning and radiomics for predicting preoperative Ki-67 expression level in breast cancer

 Published on 27/03/2026 |  Original article (Full-text)  | Wang Yuqian et al. | BMC Medical Imaging 2026; 26(1): 80

Breast cancer(BC) is the most common and malignant tumor in women worldwide [1]. Accurate risk stratification and timely treatment are essential for improving prognosis. The routinely used immunohistochemistry (IHC) includes Progesterone Receptor(PR), Estrogen Receptor(ER), Human Epidermal Growth Factor...