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Tumor heterogeneity index from DCE-MRI for AKT-inhibition responder identification and reveals hot immune microenvironment for patients with breast cancer: a multi-omics analysis of I-SPY2 trial

 Published on 13/02/2026 |  Original article (Full-text)  | Teng Xinzhi et al. | Breast Cancer Research 2026; 28(1): 39

The AKT/mammalian target of rapamycin (mTOR)/phosphatidylinositol-3-kinase (PI3K) signaling pathway plays a crucial role in the development, survival, and proliferation of tumor cells [1]. As a central component of the AKT/mTOR/PI3K pathway, AKT serves as an essential mediator that transmits signals...

Pleural ultrasound as an adjunct to physical examination in the preoperative evaluation of lung cancer patients

 Published on 06/02/2026 |  Original article (Full-text)  | Ismaël Bah et al. | European journal of cardio-thoracic surgery. Volume 45(5).

Preoperative evaluation of patients with suspected or confirmed lung cancer consists of clinical and radiological staging. Malignant pleural effusion is a poor prognosticator in non-small-cell lung cancer. Pleural ultrasound (PU) allows for the assessment of pleural effusion, providing real-time guidance...

Enhancing breast cancer diagnosis: non-invasive prediction of MKI-67 (Ki67) expression using ultrasound images

 Published on 30/01/2026 |  Original article (Full-text)  | Xie Hui et al. | BMC Cancer 2025; 26(1): 102

Breast cancer is one of the most common malignant tumors among women [1]. In 2020, approximately 685,000 people worldwide died from breast cancer [2]. In China, breast cancer accounts for about 10% of various malignant tumors, and the growth rate is increasing year by year, and the age of onset of patients...

Differentiating the differentiation degree of gastric cancer based on MRI radiomics

 Published on 23/01/2026 |  Original article (Full-text)  | Wang Yilin et al. | BMC Medical Imaging 2025; 26(1): 25

Gastric cancer is the fifth most common tumor with third mortality in the world. In recent decades, the incidence and mortality of gastric cancer have declined. However, due to the population growth in areas with high incidence and the improvement of diagnosis level in relevant areas, the prevalence...