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Integrated conventional ultrasound and radiomics model for predicting major pathological response to neoadjuvant therapy in triple-negative breast cancer

 Published on 28/11/2025 |  Original article (Full-text)  | Lin Ruoxuan et al. | BMC Medical Imaging 2025; 25(1): 472

Triple-negative breast cancer (TNBC), a subtype with high malignancy and poor prognosis, accounts for approximately 15%-20% of all breast cancer subtypes [1]. Due to the lack of estrogen receptor, progesterone receptor, and HER2 expression, TNBC is insensitive to endocrine therapy and HER2-targeted therapy....

Early assessment of treatment response in AML using FLT PET/cT: a trial of the ECOG-ACRIN Cancer Research Group (EAI141)

 Published on 21/11/2025 |  Original article (Full-text)  | Robert Jeraj et al. | Leukemia & Lymphoma 2025; aop:10.1080/10428194.2025.2567516

EAI141 was a prospective, multi-center trial designed to assess 3′-deoxy-3′-F-fluorothymidine (FLT) PET/CT as a treatment response biomarker. The primary was to evaluate the negative predictive value (NPV) of post-treatment ‘day 14' FLT-uptake (clinically non-responding patients with...

Multi-regional feature integration on enhanced CT for lymph node metastasis prediction in gastric cancer: a novel radiomics approach

 Published on 14/11/2025 |  Original article (Full-text)  | Shi Ang et al. | BMC Medical Imaging 2025; 25(1): 419

Gastric cancer (GC) constitutes a major global health burden, ranking among the leading causes of cancer-related mortality. Recent epidemiological data reveal staggering annual estimates of 1.23 million new diagnoses and 954,000 deaths worldwide [1, 2], underscoring the urgent need for precision management...

AI-driven MRI biomarker for triple-class HER2 expression classification in breast cancer: a large-scale multicenter study

 Published on 07/11/2025 |  Original article (Full-text)  | Wong Chinting et al. | Breast Cancer Research 2025; 27(1): 165

Breast cancer is the most prevalent malignancy and a leading cause of cancer-related mortality among women worldwide [1]. The human epidermal growth factor receptor 2 (HER2) is a critical biomarker and therapeutic target in breast cancer, influencing both treatment response and disease progression [2,...

The feasibility of the radiomics models for tumor-infiltrating lymphocytes level prediction in breast cancer based on dynamic contrast-enhanced MRI

 Published on 01/11/2025 |  Original article (Full-text)  | Peng Yuan et al. | BMC Medical Imaging 2025; 25(1): 420

Breast cancer has emerged as the most prevalent malignant neoplasm globally and represents the second leading cause of cancer-related mortality among women worldwide [1]. Given the pronounced heterogeneity characteristic of breast cancer, the identification of optimal therapeutic strategies tailored...