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A nomogram based on dual-layer spectral detector CT-derived 40KeV virtual monoenergetic images for preoperative prediction of simultaneous distant metastasis in colorectal cancer

 Published on 12/12/2025 |  Original article (Full-text)  | Sun Qi et al. | BMC Medical Imaging 2025; 25(1): 455

Colorectal cancer (CRC) is currently the third most common malignant tumor in the world in terms of incidence rate and the second most common in terms of mortality rate, and the incidence is increasing year by year, and Asia is the region with the highest incidence (51.8%) and mortality rate (52.4%)...

Clinical outcomes of ultrasound-guided mammotome vacuum-assisted excision for benign breast tumors and its impact on serum tumor markers

 Published on 05/12/2025 |  Original article (Full-text)  | He Yong et al. | BMC Surgery 2025; 25(1): 565

Benign breast lesions, including fibroadenoma, adenosis, papilloma, and benign phyllodes tumors, are prevalent globally and in China. These lesions, while non-cancerous, can mimic malignant tumors [1, 2]. Management of benign breast lesions ranges from observation to excision Emerging minimally invasive...

Integrated conventional ultrasound and radiomics model for predicting major pathological response to neoadjuvant therapy in triple-negative breast cancer

 Published on 28/11/2025 |  Original article (Full-text)  | Lin Ruoxuan et al. | BMC Medical Imaging 2025; 25(1): 472

Triple-negative breast cancer (TNBC), a subtype with high malignancy and poor prognosis, accounts for approximately 15%-20% of all breast cancer subtypes [1]. Due to the lack of estrogen receptor, progesterone receptor, and HER2 expression, TNBC is insensitive to endocrine therapy and HER2-targeted therapy....

Early assessment of treatment response in AML using FLT PET/cT: a trial of the ECOG-ACRIN Cancer Research Group (EAI141)

 Published on 21/11/2025 |  Original article (Full-text)  | Robert Jeraj et al. | Leukemia & Lymphoma 2025; aop:10.1080/10428194.2025.2567516

EAI141 was a prospective, multi-center trial designed to assess 3′-deoxy-3′-F-fluorothymidine (FLT) PET/CT as a treatment response biomarker. The primary was to evaluate the negative predictive value (NPV) of post-treatment ‘day 14' FLT-uptake (clinically non-responding patients with...

Multi-regional feature integration on enhanced CT for lymph node metastasis prediction in gastric cancer: a novel radiomics approach

 Published on 14/11/2025 |  Original article (Full-text)  | Shi Ang et al. | BMC Medical Imaging 2025; 25(1): 419

Gastric cancer (GC) constitutes a major global health burden, ranking among the leading causes of cancer-related mortality. Recent epidemiological data reveal staggering annual estimates of 1.23 million new diagnoses and 954,000 deaths worldwide [1, 2], underscoring the urgent need for precision management...