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The design of multi-target ligands and their role in schizophrenia therapy: an update
Schizophrenia
 1 min.

 Published on 02/06/2026 |  Original article (Full-text)  | Zarko Gagic et al. | Expert opinion on drug discovery 2026; 21(6): 593-608

Schizophrenia is a complex psychiatric disorder with a partially understood pathophysiology involving multiple neurotransmitter systems and receptor families in its onset and progression. Modern therapeutic approaches for effective schizophrenia treatment require multi-target drug actions that exert...

Preparation and evaluation of Prochlorperazine Maleate loaded nanostructured lipid carrier for the treatment of schizophrenia
Schizophrenia
 1 min.

 Published on 26/05/2026 |  Original article (Full-text)  | Karan Maniar et al. | Therapeutic Delivery 2026; aop:10.1080/20415990.2026.2676411

Schizophrenia management using conventional oral antipsychotic formulations is constrained by poor bioavailability, extensive first-pass metabolism, and dose-related systemic adverse effects. Intranasal drug delivery using nanocarrier systems has emerged as a promising strategy for direct brain targeting...

Analyzing the direct medical cost of schizophrenia in Hospital Pulau Pinang, Malaysia
Schizophrenia
 1 min.

 Published on 19/05/2026 |  Original article (Full-text)  | Fuad Fadhel Alotaibi et al. | Expert Review of Pharmacoeconomics & Outcomes Research 2026; aop:10.1080/14737167.2026.2659625

Schizophrenia (SCZ) is a major public health concern that places a significant economic burden on healthcare systems. This study assessed the direct medical costs of SCZ and examined cost drivers at Hospital Pulau Pinang (HPP), Malaysia. To estimate and compare direct medical costs for SCZ patients across...

The Cancer Screening Disparity among Women With Schizophrenia by Co-occurring Chronic Physical Illness Status: A Nationwide Cohort Study in Taiwan
Schizophrenia
 1 min.

 Published on 12/05/2026 |  Original article (Full-text)  | Ching-Ching Claire Lin et al. | Schizophrenia bulletin. Volume 52(2).

To investigate the association between co-occurring chronic physical illnesses (CPIs) and breast and cervical cancer screening rates among women with schizophrenia in Taiwan. Study Methods: This retrospective cohort study analyzed Taiwan National Health Insurance claims data from 2017 to 2019. The sample...