SchizophreniaArchives
Trajectory analysis of BMI increase induced by second-generation antipsychotics in first-episode schizophrenia: a secondary analysis based on CNFEST****
Schizophrenia 5 min.
Schizophrenia, affecting approximately 0.7% of the global population1, reduces life expectancy by over a decade2, and imposes profound personal and societal burden3,4. While second-generation antipsychotics (SGAs) remain the primary pharmacological intervention for schizophrenia, their metabolic adverse...
Distinct microRNA profiles in neuron-derived extracellular vesicles between recent-onset and chronic-phase schizophrenia
Schizophrenia 6 min.
MicroRNAs (miRNAs) are small non-coding RNAs, composed of 20–24 nucleotides that regulate gene expression by binding to mRNAs with complementary sequences, leading to their degradation or inhibition of protein translation1. They play crucial roles in various biological processes, including neurogenesis...
Spatiotemporal dynamics of RERE in schizophrenia pathogenesis: insights from multi-omics and single-cell sequencing
Schizophrenia 9 min.
Schizophrenia (SCZ) is a severe neurodevelopmental disorder that affects approximately 24 million individuals globally, equating to 1 in 300 individuals (0.32%)1,2. It is commonly associated with significant cognitive impairment and social functional decline. The disease imposes an annual economic burden...
Risk of Schizophrenia After a Diagnosis of Epilepsy: A Nationwide Matched Cohort Study in South Korea.
Schizophrenia 1 min.
Epilepsy is associated with increased schizophrenia risk, but few large studies account for key factors. This study analyzed cohort data from Korea to assess schizophrenia risk postepilepsy diagnosis. Methods: Epilepsy patients were age-matched and sex-matched with controls. Schizophrenia was the primary...
