SchizophreniaArchives
Plasma Fatty Acid Metabolites as Biomarkers of Metabolic Syndrome and Clinical Features in Chronic Schizophrenia
Schizophrenia 1 min.
Metabolic syndrome (MetS) is a major risk factor for cardiovascular disease in schizophrenia (SCZ), yet its metabolic underpinnings, particularly in chronic SCZ, remain unclear. This study investigated plasma metabolic profiles and their associations with clinical features in chronic SCZ. Study Design:...
Multilayer network analysis reveals instability of brain dynamics in untreated first-episode schizophrenia
Schizophrenia 1 min.
Although aberrant static functional brain network activity has been reported in schizophrenia, little is known about how the dynamics of neural function are altered in first-episode schizophrenia and are modulated by antipsychotic treatment. The baseline resting-state functional magnetic resonance imaging...
The identification of novel schizophrenia-related metabolites using untargeted lipidomics
Schizophrenia 1 min.
Human lipidome still remains largely unexplored among Chinese schizophrenia patients. We aimed to identify novel lipid molecules associated with schizophrenia and cognition among schizophrenia patients. The current study included 96 male schizophrenia patients and 96 gender-matched healthy controls....
Autophagy in Schizophrenia: A Continuum From Developmental Vulnerability to Progressive Neuronal Stress? A Scoping Review
Schizophrenia 1 min.
Autophagy, the cell's primary degradation and recycling system, is essential for neuronal homeostasis. A structured synthesis of studies directly investigating autophagy in schizophrenia (SCZ) is lacking. This scoping review aimed to map the available evidence directly assessing autophagy processes in...
