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Two structural alteration patterns of the thalamus in patients with schizophrenia
Schizophrenia
 6 min.

 Published on 16/12/2025 |  Original article (Full-text)  | Yu Wei et al. | BMC Medicine 2025; 23(1): 679

Schizophrenia is a severe psychiatric disorder, characterized by considerable heterogeneity, imposing a significant healthcare burden globally [1, 2]. Cognitive impairment, as a core symptom of schizophrenia, substantially contributes to functional disability among affected individuals [3] and often...

Adjunctive High-Definition Transcranial Direct Current Stimulation in Treatment of Resistant Auditory Verbal Hallucinations in Schizophrenia: A Randomized Sham-Controlled Trial.
Schizophrenia
 1 min.

 Published on 09/12/2025 |  Original article (Full-text)  | Mahato, Apurba Narayan MBBS, MD et al. | Journal of ECT. Volume 41(4).

Resistant auditory verbal hallucination (AVH) remains a disabling symptom in schizophrenia. Transcranial direct current stimulation (tDCS) and its more targeted variant, high-definition tDCS (HD-tDCS), have shown promising results in reducing AVH. We aimed to determine the effects of adjunctive HD-tDCS...

How researchers refer to individuals with schizophrenia: person-first and identity-first language in academic papers
Schizophrenia
 4 min.

 Published on 02/12/2025 |  Original article (Full-text)  | Dino Maria et al. | Schizophrenia 2025; 11(1): 146

Stigma encompasses negative beliefs and attitudes that result in behaviors characterized by avoidance, rejection, or fear of people perceived as different1. Among mental conditions, schizophrenia stands out as one of the most stigmatized2,3. Even today, people often associate schizophrenia with predetermined...

Resolving the heterogeneity of dopamine subsystems dysfunction in schizophrenia: a PET meta-analysis
Schizophrenia
 6 min.

 Published on 25/11/2025 |  Original article (Full-text)  | Zhao Zhen et al. | Schizophrenia 2025; 11(1): 139

The “dopamine hypothesis” is one of the leading pathoetiologic theories of schizophrenia and has undergone significant evolution since its inception1, 2–3. The classical hypothesis was originally proposed in the mid-20th century following the discovery of antipsychotic drugs dopamine...