LungArchives
Benchmarking Large Language Models Using a Best Evidence Topic Report in a Patient With Early Non-Small Cell Lung Cancer
Lung 1 min.
Large language models (LLMs) are generative-AI which generate text output like a human conversation. We wanted to assess the ability of LLMs to answer patient's questions and benchmark their output using a best evidence topic (BET). Methods: We asked LLMs whether robot-assisted thoracic surgery (RATS)...
Brief Report: Critical Role for DNA-Based Sequencing in Discriminating Distinct Primary Lung Cancers With Different MET Exon 14 Skipping Mutations
Lung 1 min.
MET exon 14 (METex14) skipping mutations are found in 3% to 4% of NSCLC and can be detected through DNA- or RNA-based sequencing assays. Although RNA sequencing simply reports skipping of exon 14, DNA sequencing assays indicate the precise DNA nucleotide changes that result in METex14 skipping. Here,...
Impact of proton pump inhibitor use on immune-related adverse events in patients with non-small cell lung cancer: a retrospective study
Lung 4 min.
Immune checkpoint inhibitors (ICIs) have become a cornerstone in the treatment of various solid tumors, including lung cancer, profoundly transforming therapeutic strategies over the past decade. Combination therapy with ICIs and cytotoxic chemotherapy is now widely established as the standard first-line...
RORγ drives non-small cell lung cancer progression by upregulating the NGF signaling
Lung 6 min.
Lung cancer is a malignant tumor with the highest global incidence and mortality rates [1]. Non-small cell lung cancer (NSCLC), the most prevalent form of the disease, accounts for approximately 85% of all lung cancer cases [2]. Recent breakthroughs in targeted therapies have significantly improved the...
