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Clinical determinants and biomarkers for predicting chemotherapeutic response in advanced non-small cell lung cancer: a single-center retrospective study
Lung
 1 min.

 Published on 16/06/2026 |  Original article (Full-text)  | Ling Zhang et al. | Immunotherapy 2026; 18(5-6): 355-363

To evaluate clinical determinants and predictive biomarkers for response to platinum-based doublet chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). This retrospective study included 200 advanced NSCLC patients (Jan 2021–Jun 2023) stratified into responders (n = 54)...

Expression levels of microRNA-550a-5p in patients with spinal metastases from non-small cell lung cancer
Lung
 1 min.

 Published on 09/06/2026 |  Original article (Full-text)  | Haifa Guo et al. | Personalized Medicine 2026; aop:10.1080/17410541.2026.2678224

This study aimed to investigate the expression levels of microRNA-550a-5p (miR-550a-5p) in patients with spinal metastases from non-small cell lung cancer (NSCLC) and to explore its clinical significance. Serum miR‑550a‑5p levels were measured by RT‑qPCR in NSCLC patients with spinal...

ARIAN protocol: a phase III study of sacituzumab and zimberelimab for the treatment of patients with non-small cell lung cancer
Lung
 1 min.

 Published on 02/06/2026 |  Original article (Full-text)  | Mariano Provencio et al. | Expert opinion on biological therapy 2026; 26(5): 441-449

Lung cancer remains the leading cause of cancer-related deaths worldwide. Despite advances to improve treatment in resectable early-stage and locally advanced non-small cell lung cancer (NSCLC), survival rates after 5 years remain low, with a high risk of disease progression. Patients who fail...

LUMINATE-101-Maccabi: a real-world study of treatment patterns and clinical outcomes in patients with non-squamous metastatic non-small cell lung cancer in an Israeli Health Maintenance Organization (HMO)
Lung
 1 min.

 Published on 26/05/2026 |  Original article (Full-text)  | Sarah Sharman Moser et al. | Expert Review of Anticancer Therapy 2026; aop:10.1080/14737140.2026.2671251

Treatment options for non-small cell lung cancer (NSCLC) patients lacking actionable genetic alterations (non-AGA) remain limited, particularly after first-line (1L) therapy. This study evaluated real-world treatment patterns and outcomes among second or later-line (2L+) patients with non-AGA non-squamous...