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Brain radiotherapy combined with immune checkpoint inhibitors and chemotherapy as first-line treatment for advanced non-small cell lung cancer with brain metastases: a retrospective study
Lung
 5 min.

 Published on 17/02/2026 |  Original article (Full-text)  | Wu Wenjie et al. | BMC Immunology 2026; 27(1): 12

Lung cancer ranks as the second most common malignancy worldwide, accounting for about 11.4% of all new cancer diagnoses [1]. Brain metastases (BM) are a frequent complication of advanced non-small cell lung cancer (NSCLC), despite the protective role of the blood–brain barrier (BBB).Around 10%...

Clinical outcomes and predictive factors of immunotherapy efficacy in non-small-cell lung cancer brain metastases: a comparative study
Lung
 5 min.

 Published on 10/02/2026 |  Original article (Full-text)  | Wei Yuxi et al. | BMC Cancer 2025; 26(1): 198

As of 2022, lung cancer remained the most commonly diagnosed malignancy and the leading cause of cancer-related death worldwide [1]. Non‑small cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancer cases [2]. Brain metastases (BMs) represent one of the most frequent metastatic...

Network pharmacology analysis and in vitro experimental validation of liriodenine against non-small cell lung cancer
Lung
 7 min.

 Published on 03/02/2026 |  Original article (Full-text)  | Yang Jing et al. | BMC Cancer 2025; 26(1): 158

According to the latest statistics from GLOBOCAN 2022, lung cancer accounts for 12.4% of all malignant tumors globally and is responsible for 18.7% of cancer-related deaths, ranking first in both incidence and mortality among all cancers [1]. Lung cancer is primarily classified into non-small cell lung...

Biomarker study on pneumonitis in durvalumab maintenance therapy after chemoradiotherapy for stage III non-small cell lung cancer
Lung
 4 min.

 Published on 27/01/2026 |  Original article (Full-text)  | Yano Ryo et al. | BMC Cancer 2025; 26(1): 113

The standard treatment for stage III non-small cell lung cancer (NSCLC) is platinum-based concurrent chemoradiotherapy (CCRT), followed by durvalumab (anti-programmed death ligand-1 [PD-L1] antibody) maintenance therapy [1]. However, the 5-year survival rate for unresectable NSCLC remains unsatisfactory...

Minimally invasive segmentectomy for non-small cell lung cancer (NSCLC): a comparative analysis of robotic and thoracoscopic approaches
Lung
 5 min.

 Published on 20/01/2026 |  Original article (Full-text)  | Malik Zeeshan et al. | BMC Surgery 2025; 26(1): 36

Lung segmentectomy is an anatomical resection that removes one or more bronchopulmonary segments while preserving healthy surrounding tissue. Unlike lobectomy, which involves resecting an entire lobe, segmentectomy targets smaller anatomical units, offering a lung-sparing alternative for early-stage...