
Prostate cancer and its treatment can impact health-related quality of life. Evidence for physical activity strategies sustained over long periods to improve quality of life is limited. Given the limited feasibility of a randomized trial to answer this question, we emulated a target trial of physical...

This study aimed to design and synthesize three new selenium adducts to evaluate their anticancer potential against human prostate cancer (PC3) and cervical cancer (HeLa) cell lines using MTT assays. Imidazole-based selenium adducts, 1,3-dipropyl-1,3-dihydro-2H-imidazole-2-selen one (C ...

This study evaluated the cost-effectiveness of hypofractionated intensity-modulated radiation therapy delivered in 20 fractions (IMRT-20) compared with robot-assisted radical prostatectomy (RARP) for patients with localized low-risk prostate cancer in Japan. A state-transition Markov model was developed...

Benign prostatic hyperplasia (BPH) is a widely observed disorder in older men, with substantial evidence indicating that cellular senescence serves a pivotal function in its progression. This investigation seeks to pinpoint cellular senescence-related genes causally connected with BPH and to examine...

A man in his sixties with locally advanced prostate cancer underwent ultra-low pressure robotic-assisted radical prostatectomy (RARP) with pelvic lymph node dissection (PLND) and was safely discharged the same day. This is the first reported UK case of day-case RARP with PLND performed at 6 mmHg. The...