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Prostate Cancer & BPHArchives

Guideline-based physical activity and health-related quality of life among prostate cancer survivors: a target trial emulation in the Health Professionals Follow-up Study

 Published on 01/05/2026 |  Original article (Full-text)  | Naiyu Chen et al. | American Journal of Epidemiology. Volume 195(4).

Prostate cancer and its treatment can impact health-related quality of life. Evidence for physical activity strategies sustained over long periods to improve quality of life is limited. Given the limited feasibility of a randomized trial to answer this question, we emulated a target trial of physical...

Mechanosynthesis and computational studies of new imidazole-based selenium adducts as potential anticancer agents against human prostate and cervical cancer

 Published on 24/04/2026 |  Original article (Full-text)  | Ghazanfar Abbas et al. | Future Medicinal Chemistry 2026; aop:10.1080/17568919.2026.2648984

This study aimed to design and synthesize three new selenium adducts to evaluate their anticancer potential against human prostate cancer (PC3) and cervical cancer (HeLa) cell lines using MTT assays. Imidazole-based selenium adducts, 1,3-dipropyl-1,3-dihydro-2H-imidazole-2-selen one (C ...

Cost-effectiveness analysis of intensity modulated radiation therapy versus robot-assisted radical prostatectomy for patients with low-risk prostate cancer in Japan

 Published on 17/04/2026 |  Original article (Full-text)  | Ataru Igarashi et al. | Journal of Radiation Research. Volume 67(2).

This study evaluated the cost-effectiveness of hypofractionated intensity-modulated radiation therapy delivered in 20 fractions (IMRT-20) compared with robot-assisted radical prostatectomy (RARP) for patients with localized low-risk prostate cancer in Japan. A state-transition Markov model was developed...

Elucidating Cellular Senescence-related Genes in Benign Prostatic Hyperplasia Through Mendelian Randomization and Single-cell RNA Sequencing

 Published on 10/04/2026 |  Original article (Full-text)  | Yichuan Wang et al. | The journals of gerontology. Series A. Volume 80(7).

Benign prostatic hyperplasia (BPH) is a widely observed disorder in older men, with substantial evidence indicating that cellular senescence serves a pivotal function in its progression. This investigation seeks to pinpoint cellular senescence-related genes causally connected with BPH and to examine...

Ultra low pressure robotic assisted radical prostatectomy (RARP) with pelvic lymph node dissection performed as a day case: first reported case in the UK

 Published on 03/04/2026 |  Original article (Full-text)  | Mayas Rddah et al. | Journal of surgical case reports. Volume 2026(1).

A man in his sixties with locally advanced prostate cancer underwent ultra-low pressure robotic-assisted radical prostatectomy (RARP) with pelvic lymph node dissection (PLND) and was safely discharged the same day. This is the first reported UK case of day-case RARP with PLND performed at 6 mmHg. The...