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Prostate Cancer & BPHArchives

Fusion genes in precision oncology: prostate cancer as a diagnostic case study
Prostate Cancer & BPH
 1 min.

 Published on 22/05/2026 |  Original article (Full-text)  | Rebecca A. Morgan et al. | Expert Review of Molecular Diagnostics 2026; aop:10.1080/14737159.2026.2669277

Fusion genes represent one of the most specific molecular alterations in human cancer and have long served as important diagnostic and therapeutic biomarkers. Advances in next-generation sequencing have driven a rapid expansion in fusion gene discovery. Clinical translation has lagged however, particularly...

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Drinking water nitrate, disinfection byproducts, and prostate cancer incidence in the Agricultural Health Study
Prostate Cancer & BPH
 1 min.

 Published on 15/05/2026 |  Original article (Full-text)  | Maya Spaur et al. | Journal of the National Cancer Institute. Volume 118(4).

Drinking water can be an important source of exposure to nitrate and disinfection by-products, including trihalomethanes (THMs) and haloacetic acids (HAAs). N-nitroso compounds formed endogenously after nitrate ingestion are animal carcinogens, and THM and HAA exposures increase the risk of some cancers....

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Long-term performance of the Gleason score in predicting metastatic and fatal prostate cancer
Prostate Cancer & BPH
 1 min.

 Published on 08/05/2026 |  Original article (Full-text)  | Zhike Lin et al. | American Journal of Epidemiology. Volume 195(4).

The time dependence in the performance of prognostic factors for cancer survival is typically incompletely understood, including in prostate cancer. We applied a "cumulative/dynamic" time-varying area under the curve (tAUC) for cumulative incidence of lethal prostate cancer (metastases/cancer-specific...

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Guideline-based physical activity and health-related quality of life among prostate cancer survivors: a target trial emulation in the Health Professionals Follow-up Study
Prostate Cancer & BPH
 1 min.

 Published on 01/05/2026 |  Original article (Full-text)  | Naiyu Chen et al. | American Journal of Epidemiology. Volume 195(4).

Prostate cancer and its treatment can impact health-related quality of life. Evidence for physical activity strategies sustained over long periods to improve quality of life is limited. Given the limited feasibility of a randomized trial to answer this question, we emulated a target trial of physical...

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Mechanosynthesis and computational studies of new imidazole-based selenium adducts as potential anticancer agents against human prostate and cervical cancer
Prostate Cancer & BPH
 1 min.

 Published on 24/04/2026 |  Original article (Full-text)  | Ghazanfar Abbas et al. | Future Medicinal Chemistry 2026; 18(9): 1059-1069

This study aimed to design and synthesize three new selenium adducts to evaluate their anticancer potential against human prostate cancer (PC3) and cervical cancer (HeLa) cell lines using MTT assays. Imidazole-based selenium adducts, 1,3-dipropyl-1,3-dihydro-2H-imidazole-2-selen one (C ...

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