Skin Barrier Science: Archives News of the month
Chronic Hand Eczema (CHE): A Narrative Review
Skin Barrier Science 8 min.
Chronic hand eczema (CHE) is a common skin disorder which often represents a challenge for both the patient and the clinician. The diagnosis is established on the basis of the persistence of hand dermatitis lasting for more than 3 months or causing at least two flares in a year. From a pathophysiological...
Computational histology reveals that concomitant application of insect repellent with sunscreen impairs UV protection in an ex vivo human skin model
Skin Barrier Science 7 min.
Skin is the largest organ in the body and covers its entire external surface, acting as a biological barrier. Evolution of human skin barrier is characterized by specific genetic changes that have occurred since humans diverged from their ancestors [1] and thereafter into separate populations [2]. On...
Cellulite & Skin Tightening: A Review of Pathophysiology and Topical Treatment
Skin Barrier Science 5 min.
Cellulite, also known as edematofibrosclerotic panniculopathy, gynoid lipodystrophy, or nodular liposclerosis [1], is a localized metabolic and aesthetic change of the skin's topography that affects both the dermis and subcutaneous tissue [2]. It manifests as dimpled or dented skin, predominantly in...
Long-Term Efficacy and Tolerability of an Emollient Containing Glycerol and Paraffin for Moderate-to-Severe Uremic Xerosis: A Randomized Phase 3 Study
Skin Barrier Science 6 min.
Uremic xerosis is one of the most common cutaneous complications of maintenance renal dialysis (MRD) among patients with end-stage renal disease (ESRD). The pathogenic and clinical features of uremic xerosis have been reviewed elsewhere [1]; however, it is a poorly recognized condition for which therapeutic...
Influence of Cosmetic Skincare Products with pH<5 on the Skin Microbiome: A Randomized Clinical Evaluation
Skin Barrier Science 6 min.
The skin serves as the outermost boundary between the human body and the environment and functions as a protective shield preventing the entry of external pathogens [1,2,3,4,5]. At the same time, it accommodates the resident commensal microbiota, also called the microbiome [2, 6, 7]. This microbial community...
