Skin Barrier ScienceArchives
Isotretinoin-Induced Sacroiliitis: New Clinical Insights and Magnetic Resonance Imaging-Based Outcomes in a Real-Life Clinical Setting.
Skin Barrier Science 1 min.
Isotretinoin, a frequently prescribed treatment for severe acne vulgaris, is associated with rare but clinically important musculoskeletal adverse effects, notably sacroiliitis. Although previous studies reported an association, comprehensive long-term data on clinical outcomes, imaging progression,...
Atopic Dermatitis Successfully Treated with Lebrikizumab in Real-World Clinical Practice in Czech Republic: A Case Series
Skin Barrier Science 3 min.
Atopic dermatitis (AD) is a complex, immune-mediated, chronic inflammatory skin disease characterized by intense pruritus and recurrent dry, red, and excoriated lesions which can have a significant impact on quality of life (QoL) and emotional well-being [1,2,3,4,5]. The prevalence of AD varies in different...
Focused update: Guidelines of care for the management of atopic dermatitis in adults
Skin Barrier Science 1 min.
In 2023 and 2024, the American Academy of Dermatology published guidelines on the use of topical and systemic therapies for the management of atopic dermatitis (AD) in adults. Since the publication of these guidelines, several novel therapies have emerged to treat AD. To update previous guidelines on...
UDP-glucose ceramide glucosyltransferase promotes radioresistance via membrane reorganization to maintain redox balance in glioblastoma
Skin Barrier Science 8 min.
Glioblastoma (GBM) is a highly aggressive and lethal brain tumor characterized by inevitable recurrence and resistance to standard therapies such as radiotherapy and temozolomide (TMZ) [1, 2–3]. Even after maximal surgical resection and chemoradiation, GBM tumors often relapse within the irradiated...
Clinical Efficacy of a Salicylic Acid-Containing Gel on Acne Management and Skin Barrier Function: A 21-Day Prospective Study.
Skin Barrier Science NaN min.
Acne vulgaris is a common skin condition characterized by excessive sebum production, inflammation, and compromised skin barrier function. Effective treatments should target both lesion reduction and skin hydration while maintaining tolerability.Objective: This study aimed to evaluate the efficacy and...
