
Acne vulgaris is a chronic skin condition of the pilosebaceous unit with a multifactorial and intricate pathophysiology that includes increased sebum production, androgenic hormonal effects, follicular hyperkeratinization, and bacterial hyperproliferation [1, 2–3]. Acne lesions may range from mild,...

Given that the product of glucosylceramide (GlcCer) catabolism is ceramide, it is reasonable to assume that cells will produce less ceramide in Gaucher disease (GD), as GlcCer catabolism is impaired by defective acid beta-glucocerebrosidase (GCase) activity. However, ceramide is also generated from the...

Emerging evidence reveals significant epidemiologic, genetic, and immunologic connections between atopic dermatitis, vitiligo, and alopecia areata, challenging previously established notions of their distinct pathogenic and molecular signatures. Exploring these commonalities not only enhances our understanding...

Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by substantial clinical heterogeneity, posing significant challenges to clinicians in diagnosis, severity stratification, and management. Artificial intelligence (AI) has emerged as a transformative tool in medicine and dermatology,...

Acne vulgaris is a common skin condition characterized by excessive sebum production, inflammation, and compromised skin barrier function. Effective treatments should target both lesion reduction and skin hydration while maintaining tolerability.Objective: This study aimed to evaluate the efficacy and...