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Skin Barrier ScienceArchives

Insulin Resistance and Blood Pressure Control on Cognitive Outcomes.
Skin Barrier Science
 1 min.

 Published on 05/01/2026 |  Original article (Full-text)  | Fan, Chenyu et al. | Hypertension. Volume 83(1).

The influence of IR (insulin resistance) on the response of patients with hypertension to intensive systolic blood pressure treatment in terms of cognitive performance remains unclear, as does which circulating metabolites mediate this process. METHODS: This study comprised a post hoc analysis of the...

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Transdermal Delivery of Poly-l-Lactic Acid via Fractional Microneedle Radiofrequency for Atrophic Acne Scars: A Split-Face Randomized Study in Fitzpatrick Skin Types III to V
Skin Barrier Science
 4 min.

 Published on 29/12/2025 |  Original article (Full-text)  | Rosalyn Kupwiwat et al. | Dermatology and therapy 2025; aop: 10.1007/s13555-025-01626-5

Atrophic acne scars (AAS) are among the most common long-term sequelae of acne vulgaris, resulting from collagen degradation and subsequent fibrosis after inflammatory resolution [1]. These scars are typically classified into three morphological types—icepick, boxcar, and rolling—each requiring...

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Isotretinoin-Induced Sacroiliitis: New Clinical Insights and Magnetic Resonance Imaging-Based Outcomes in a Real-Life Clinical Setting.
Skin Barrier Science
 1 min.

 Published on 22/12/2025 |  Original article (Full-text)  | Erol, Kemal et al. | JCR: Journal of Clinical Rheumatology. Volume 31(8).

Isotretinoin, a frequently prescribed treatment for severe acne vulgaris, is associated with rare but clinically important musculoskeletal adverse effects, notably sacroiliitis. Although previous studies reported an association, comprehensive long-term data on clinical outcomes, imaging progression,...

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Atopic Dermatitis Successfully Treated with Lebrikizumab in Real-World Clinical Practice in Czech Republic: A Case Series
Skin Barrier Science
 3 min.

 Published on 15/12/2025 |  Original article (Full-text)  | Marie Jandová et al. | Dermatology and therapy 2025; aop: 10.1007/s13555-025-01608-7

Atopic dermatitis (AD) is a complex, immune-mediated, chronic inflammatory skin disease characterized by intense pruritus and recurrent dry, red, and excoriated lesions which can have a significant impact on quality of life (QoL) and emotional well-being [1,2,3,4,5]. The prevalence of AD varies in different...

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Focused update: Guidelines of care for the management of atopic dermatitis in adults
Skin Barrier Science
 1 min.

 Published on 08/12/2025 |  Original article (Full-text)  | Davis, Dawn M.R. et al. | Journal of the American Academy of Dermatology 2025; 93(3): 745.e1-745.e7

In 2023 and 2024, the American Academy of Dermatology published guidelines on the use of topical and systemic therapies for the management of atopic dermatitis (AD) in adults. Since the publication of these guidelines, several novel therapies have emerged to treat AD. To update previous guidelines on...

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