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Skin Barrier ScienceArchives

Bidirectional causal association and shared anti-inflammatory target of asthma and atopic dermatitis: a Mendelian randomization and colocalisation study
Skin Barrier Science
 7 min.

 Published on 12/01/2026 |  Original article (Full-text)  | Bi Jirui et al. | BMC Pulmonary Medicine 2025; 26(1): 5

Asthma is one of the most prevalent chronic and non-communicable diseases, characterized by variable respiratory symptoms and airflow limitation [1]. Atopic dermatitis (AD) represents a chronic and non-infectious dermatosis, characterized by persistent pruritus of the skin [2]. Both conditions are widely...

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Insulin Resistance and Blood Pressure Control on Cognitive Outcomes.
Skin Barrier Science
 1 min.

 Published on 05/01/2026 |  Original article (Full-text)  | Fan, Chenyu et al. | Hypertension. Volume 83(1).

The influence of IR (insulin resistance) on the response of patients with hypertension to intensive systolic blood pressure treatment in terms of cognitive performance remains unclear, as does which circulating metabolites mediate this process. METHODS: This study comprised a post hoc analysis of the...

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Transdermal Delivery of Poly-l-Lactic Acid via Fractional Microneedle Radiofrequency for Atrophic Acne Scars: A Split-Face Randomized Study in Fitzpatrick Skin Types III to V
Skin Barrier Science
 4 min.

 Published on 29/12/2025 |  Original article (Full-text)  | Rosalyn Kupwiwat et al. | Dermatology and therapy 2025; aop: 10.1007/s13555-025-01626-5

Atrophic acne scars (AAS) are among the most common long-term sequelae of acne vulgaris, resulting from collagen degradation and subsequent fibrosis after inflammatory resolution [1]. These scars are typically classified into three morphological types—icepick, boxcar, and rolling—each requiring...

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Isotretinoin-Induced Sacroiliitis: New Clinical Insights and Magnetic Resonance Imaging-Based Outcomes in a Real-Life Clinical Setting.
Skin Barrier Science
 1 min.

 Published on 22/12/2025 |  Original article (Full-text)  | Erol, Kemal et al. | JCR: Journal of Clinical Rheumatology. Volume 31(8).

Isotretinoin, a frequently prescribed treatment for severe acne vulgaris, is associated with rare but clinically important musculoskeletal adverse effects, notably sacroiliitis. Although previous studies reported an association, comprehensive long-term data on clinical outcomes, imaging progression,...

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Atopic Dermatitis Successfully Treated with Lebrikizumab in Real-World Clinical Practice in Czech Republic: A Case Series
Skin Barrier Science
 3 min.

 Published on 15/12/2025 |  Original article (Full-text)  | Marie Jandová et al. | Dermatology and therapy 2025; aop: 10.1007/s13555-025-01608-7

Atopic dermatitis (AD) is a complex, immune-mediated, chronic inflammatory skin disease characterized by intense pruritus and recurrent dry, red, and excoriated lesions which can have a significant impact on quality of life (QoL) and emotional well-being [1,2,3,4,5]. The prevalence of AD varies in different...

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