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Cardiomyocyte derived extracellular mitochondria in activation of macrophages during oxidative stress

 Published on 13/04/2026 |  Original article (Full-text)  | Lenee Shrestha et al. | Cardiovascular Research. Volume 122(5).

Mitochondria serve as central hubs for aerobic metabolism and regulators of cell fate. Damage to mitochondria induced by oxidative stress contributes to cardiac injury. We investigate whether oxidative stress causes the release of mitochondria into the extracellular space and whether these extracellular...

Towards the definition of disease phenotypes in paediatric SAPHO syndrome: a national multicentric study

 Published on 06/04/2026 |  Original article (Full-text)  | Caterina Matucci-Cerinic et al. | Rheumatology. Volume 64(6).

The of this study was to confirm the presence of different disease phenotypes of paediatric SAPHO syndrome (pSAPHO) based on their skin manifestations in a large cohort of Italian patients. Methods: Patients with pSAPHO were enrolled in the Eurofever Registry and the data retrospectively analysed. The...

Examining the impact of child atopic dermatitis on maternal depression: A longitudinal cohort study

 Published on 30/03/2026 |  Original article (Full-text)  | Kang, Hannah Eunhae et al. | Journal of the American Academy of Dermatology 2026; 94(2): 539-47

Longitudinal data on mental health in caregivers of children with atopic dermatitis (AD) are limited. Examine the relationship between child AD activity and severity with maternal depression across childhood. Longitudinal cohort study of 12,124 mother–child dyads from the Avon Longitudinal Study...

Removal of volatile organic compounds by chemical filters significantly inhibited the development of atopic dermatitis symptoms in mice: potential implications for air-conditioning systems in healthcare environments

 Published on 23/03/2026 |  Original article (Full-text)  | Chiharu Ohira et al. | Toxicological Sciences. Volume 209(3).

Volatile organic compounds (VOCs) are increasingly implicated in systemic diseases, but their contribution to skin disorders such as atopic dermatitis (AD) remains unclear. This study assessed VOC concentrations in medical environments, their effects on AD development, and the efficacy of VOC removal...

Independent and joint associations of key social exposome components with cognitive aging: triangulating evidence through cross-national data

 Published on 16/03/2026 |  Original article (Full-text)  | Ruijia Chen et al. | American Journal of Epidemiology. Volume 195(2).

We examined the independent and joint associations of five key social exposome components, including financial strain, neighborhood disorder, perceived discrimination, social strain, and traumatic life events, with cognitive function levels and decline. Data were from adults aged > 50 in the US Health...