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Skin Barrier ScienceArchives

The mediterranean diet and acne vulgaris: a systematic review and meta-analysis

 Published on 17/11/2025 |  Original article (Full-text)  | Taha Sari et al. | Nutrition & Metabolism 2025; 22(1): 132

Acne vulgaris is a chronic skin condition of the pilosebaceous unit with a multifactorial and intricate pathophysiology that includes increased sebum production, androgenic hormonal effects, follicular hyperkeratinization, and bacterial hyperproliferation [1, 2–3]. Acne lesions may range from mild,...

Sphingolipids in Gaucher disease: a systematic review

 Published on 10/11/2025 |  Original article (Full-text)  | Lake Ashleigh et al. | Orphanet Journal of Rare Diseases 2025; 20(1): 563

Given that the product of glucosylceramide (GlcCer) catabolism is ceramide, it is reasonable to assume that cells will produce less ceramide in Gaucher disease (GD), as GlcCer catabolism is impaired by defective acid beta-glucocerebrosidase (GCase) activity. However, ceramide is also generated from the...

Converging paths toward unified therapeutic approaches in atopic dermatitis, vitiligo, and alopecia areata

 Published on 03/11/2025 |  Original article (Full-text)  | Tordjman, Lea et al. | The Journal of allergy and clinical immunology 2025; 156(2): 237-51

Emerging evidence reveals significant epidemiologic, genetic, and immunologic connections between atopic dermatitis, vitiligo, and alopecia areata, challenging previously established notions of their distinct pathogenic and molecular signatures. Exploring these commonalities not only enhances our understanding...

Artificial intelligence in atopic dermatitis: A narrative review

 Published on 27/10/2025 |  Original article (Full-text)  | Liu, Daniel et al. | The Journal of allergy and clinical immunology 2025; 156(4): 889-98

Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by substantial clinical heterogeneity, posing significant challenges to clinicians in diagnosis, severity stratification, and management. Artificial intelligence (AI) has emerged as a transformative tool in medicine and dermatology,...

Clinical Efficacy of a Salicylic Acid-Containing Gel on Acne Management and Skin Barrier Function: A 21-Day Prospective Study.

 Published on 08/09/2025 |  PubMed  | Liu Ye et al. | Journal of cosmetic dermatology 2025 Jul; 24(7): e70353

Acne vulgaris is a common skin condition characterized by excessive sebum production, inflammation, and compromised skin barrier function. Effective treatments should target both lesion reduction and skin hydration while maintaining tolerability.Objective: This study aimed to evaluate the efficacy and...