Skin Barrier ScienceArchives
Efficacy and safety of rocatinlimab for the treatment of moderate-to-severe atopic dermatitis in ROCKET-IGNITE and ROCKET-HORIZON: two global, double-blind, placebo-controlled, randomised phase 3 clinical trials
Skin Barrier Science 1 min.
Rocatinlimab is a T cell rebalancing therapy that inhibits and reduces the number of pathogenic T cells by targeting the OX40 receptor expressed on the surface of activated T cells. Two global phase 3 studies were performed to assess the efficacy and safety of rocatinlimab for the treatment of moderate-to-severe...
Hydrogels for acne treatment: a systematic review and meta-analysis of clinical trials
Skin Barrier Science 1 min.
Hydrogels are three-dimensional, water-rich polymer networks that enhance drug delivery, hydration, and tolerability in topical acne therapy. This systematic review and meta-analysis evaluated the efficacy and safety of hydrogel-based formulations for acne treatment. Systematic search of PubMed, Embase,...
Bidirectional causal association and shared anti-inflammatory target of asthma and atopic dermatitis: a Mendelian randomization and colocalisation study
Skin Barrier Science 7 min.
Asthma is one of the most prevalent chronic and non-communicable diseases, characterized by variable respiratory symptoms and airflow limitation [1]. Atopic dermatitis (AD) represents a chronic and non-infectious dermatosis, characterized by persistent pruritus of the skin [2]. Both conditions are widely...
Insulin Resistance and Blood Pressure Control on Cognitive Outcomes.
Skin Barrier Science 1 min.
The influence of IR (insulin resistance) on the response of patients with hypertension to intensive systolic blood pressure treatment in terms of cognitive performance remains unclear, as does which circulating metabolites mediate this process. METHODS: This study comprised a post hoc analysis of the...
Transdermal Delivery of Poly-l-Lactic Acid via Fractional Microneedle Radiofrequency for Atrophic Acne Scars: A Split-Face Randomized Study in Fitzpatrick Skin Types III to V
Skin Barrier Science 4 min.
Atrophic acne scars (AAS) are among the most common long-term sequelae of acne vulgaris, resulting from collagen degradation and subsequent fibrosis after inflammatory resolution [1]. These scars are typically classified into three morphological types—icepick, boxcar, and rolling—each requiring...
