Skin Barrier ScienceArchives
A comparative study of efficacy of fractional carbon dioxide laser with and without subcision in treatment of facial acne scars
Skin Barrier Science 1 min.
Severe acne, left untreated, lead to permanent scarring and facial deformities, causing significant physical and psychological distress. Traditional ablative lasers, while effective for treating facial atrophic acne scars, are often limited by long recovery times and complications such as erythema, hyperpigmentation,...
Health disparities in cystic fibrosis in the context of the exposome: recent developments and future directions
Skin Barrier Science 1 min.
Clinical outcomes with cystic fibrosis (CF) vary substantially even among individuals with the same cystic fibrosis transmembrane conductance regulator (CFTR) genotype due to the wide spectrum of exposures that are linked to the social determinants of health. The exposome framework offers a comprehensive...
Local prevalence and management of Janus kinase inhibitor-induced acne among adolescents with inflammatory bowel disease
Skin Barrier Science 1 min.
Janus kinase inhibitors (JAKi), including tofacitinib and upadacitinib, are small-molecule medications effective in treating inflammatory bowel disease (IBD) and other immune-mediated disorders. In adult IBD clinical trials for JAKi, acne is a commonly reported adverse event. There are currently no data...
Efficacy and safety of ruxolitinib cream for the treatment of moderate to severe chronic hand eczema: Results from a 16-week, multicenter, randomized, double-blind study
Skin Barrier Science 1 min.
Chronic hand eczema (CHE) is a well-recognized inflammatory disorder. To evaluate the efficacy and safety of 1.5% ruxolitinib cream in adults with moderate to severe CHE. This phase 2 study enrolled adults with CHE from North America and Europe, an Investigator's Global Assessment-CHE score of 3/4, ≥1...
Intralesional acyclovir versus cryotherapy in treatment of plantar warts: A randomized controlled trial
Skin Barrier Science 1 min.
Plantar warts are known for their recalcitrant nature. Intralesional acyclovir injection has been recently tried for treatment of warts. Comparing the efficacy and safety of intralesional acyclovir versus cryotherapy in treatment of plantar warts. Sixty-eight patients with plantar warts were randomized...
