Skin Barrier ScienceArchives
The relationship between MMP-2 and TIMP-2 gene polymorphisms and skin barrier function, inflammatory cytokine levels in acne patients
Skin Barrier Science 1 min.
This study aimed to investigate the association between MMP-2 rs243865 and TIMP-2 rs8179090 gene polymorphisms and skin barrier function, as well as inflammatory cytokine levels, in acne patients, to explore potential genetic mechanisms underlying acne pathogenesis. A total of 200 acne patients and 100...
Skin deep: dermatologic challenges in PCOS through the female lifespan
Skin Barrier Science 1 min.
Polycystic ovary syndrome (PCOS) is a lifelong endocrine-metabolic condition with prominent dermatologic manifestations such as hirsutism, acne/seborrhea, and female pattern hair loss (FPHL), which are frequently the initial complaint for seeking medical attention. This review explores the pathogenesis...
Correlation between ceramide and its metabolites and central precocious puberty: a cross-sectional study
Skin Barrier Science 4 min.
Sphingolipids, a class of lipids containing amino alcohol backbones, are ubiquitous in mammalian cells. Increasing evidence indicates that dysregulation of bioactive sphingolipid signaling not only contributes to the development of metabolic diseases but also mediates their pathological sequelae [1]....
Ruxolitinib Cream As-Needed Monotherapy Demonstrates Sustained Disease and Symptom Control in Patients with Mild to Moderate Atopic Dermatitis: Pooled Analysis from Two Phase 3 Studies
Skin Barrier Science 5 min.
Atopic dermatitis (AD) is a chronic, highly pruritic, inflammatory skin disease [1]. Itch and the resulting sleep disturbance significantly reduce the quality of life in patients with AD [2, 3]. There is a need for treatments that can safely maintain disease and symptom control when used over the long...
Clinical Efficacy of a Salicylic Acid-Containing Gel on Acne Management and Skin Barrier Function: A 21-Day Prospective Study.
Skin Barrier Science NaN min.
Acne vulgaris is a common skin condition characterized by excessive sebum production, inflammation, and compromised skin barrier function. Effective treatments should target both lesion reduction and skin hydration while maintaining tolerability.Objective: This study aimed to evaluate the efficacy and...
