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Skin Barrier ScienceArchives

Removal of volatile organic compounds by chemical filters significantly inhibited the development of atopic dermatitis symptoms in mice: potential implications for air-conditioning systems in healthcare environments

 Published on 23/03/2026 |  Original article (Full-text)  | Chiharu Ohira et al. | Toxicological Sciences. Volume 209(3).

Volatile organic compounds (VOCs) are increasingly implicated in systemic diseases, but their contribution to skin disorders such as atopic dermatitis (AD) remains unclear. This study assessed VOC concentrations in medical environments, their effects on AD development, and the efficacy of VOC removal...

Independent and joint associations of key social exposome components with cognitive aging: triangulating evidence through cross-national data

 Published on 16/03/2026 |  Original article (Full-text)  | Ruijia Chen et al. | American Journal of Epidemiology. Volume 195(2).

We examined the independent and joint associations of five key social exposome components, including financial strain, neighborhood disorder, perceived discrimination, social strain, and traumatic life events, with cognitive function levels and decline. Data were from adults aged > 50 in the US Health...

The relationship between MMP-2 and TIMP-2 gene polymorphisms and skin barrier function, inflammatory cytokine levels in acne patients

 Published on 09/03/2026 |  Original article (Full-text)  | Suling Huang et al. | Expert Review of Clinical Immunology 2026; 22(2): 233-241

This study aimed to investigate the association between MMP-2 rs243865 and TIMP-2 rs8179090 gene polymorphisms and skin barrier function, as well as inflammatory cytokine levels, in acne patients, to explore potential genetic mechanisms underlying acne pathogenesis. A total of 200 acne patients and 100...

Skin deep: dermatologic challenges in PCOS through the female lifespan

 Published on 02/03/2026 |  Original article (Full-text)  | Seda Hanife Oğuz et al. | Expert Review of Endocrinology & Metabolism 2026; 21(2): 123-142

Polycystic ovary syndrome (PCOS) is a lifelong endocrine-metabolic condition with prominent dermatologic manifestations such as hirsutism, acne/seborrhea, and female pattern hair loss (FPHL), which are frequently the initial complaint for seeking medical attention. This review explores the pathogenesis...

Clinical Efficacy of a Salicylic Acid-Containing Gel on Acne Management and Skin Barrier Function: A 21-Day Prospective Study.

 Published on 08/09/2025 |  PubMed  | Liu Ye et al. | Journal of cosmetic dermatology 2025 Jul; 24(7): e70353

Acne vulgaris is a common skin condition characterized by excessive sebum production, inflammation, and compromised skin barrier function. Effective treatments should target both lesion reduction and skin hydration while maintaining tolerability.Objective: This study aimed to evaluate the efficacy and...