Skin Barrier ScienceArchives
Sphingolipids in Gaucher disease: a systematic review
Skin Barrier Science 8 min.
Given that the product of glucosylceramide (GlcCer) catabolism is ceramide, it is reasonable to assume that cells will produce less ceramide in Gaucher disease (GD), as GlcCer catabolism is impaired by defective acid beta-glucocerebrosidase (GCase) activity. However, ceramide is also generated from the...
Converging paths toward unified therapeutic approaches in atopic dermatitis, vitiligo, and alopecia areata
Skin Barrier Science 1 min.
Emerging evidence reveals significant epidemiologic, genetic, and immunologic connections between atopic dermatitis, vitiligo, and alopecia areata, challenging previously established notions of their distinct pathogenic and molecular signatures. Exploring these commonalities not only enhances our understanding...
Artificial intelligence in atopic dermatitis: A narrative review
Skin Barrier Science 1 min.
Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by substantial clinical heterogeneity, posing significant challenges to clinicians in diagnosis, severity stratification, and management. Artificial intelligence (AI) has emerged as a transformative tool in medicine and dermatology,...
Exploring the association between ceramide, phosphatidylcholine, and COPD prevalence and incidence: a FINRISK population-based cohort study
Skin Barrier Science 7 min.
Chronic Obstructive Pulmonary Disease (COPD) is a significant global health burden, contributing to both morbidity and mortality worldwide. Chronic respiratory symptoms and reduced airflow result from prolonged exposure to harmful particles or gases, leading to abnormalities in the airways and alveoli...
Clinical Efficacy of a Salicylic Acid-Containing Gel on Acne Management and Skin Barrier Function: A 21-Day Prospective Study.
Skin Barrier Science NaN min.
Acne vulgaris is a common skin condition characterized by excessive sebum production, inflammation, and compromised skin barrier function. Effective treatments should target both lesion reduction and skin hydration while maintaining tolerability.Objective: This study aimed to evaluate the efficacy and...
