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Melanoma: Archives News of the month

Assessment of telomeres expression in melanoma and cutaneous squamous cell carcinoma: correlation with clinical parameters
Melanoma
 4 min.

 Published on 24/03/2025 |  Original article (Abstract)  | Tuqa Nasser Alsurhi et al. | Clinical and Translational Oncology 2025; aop: 10.1007/s12094-025-03876-3

Skin cancer is classified into two main types: melanoma and non-melanoma skin cancer (NMSC). Over the past several decades, epidemiologic studies have demonstrated an increased incidence of both non-melanoma and melanoma skin cancers [1]. Early diagnosis and treatment of these cancers represent major...

Survival Outcomes of a Large Cohort of Acral Melanoma Patients Treated at a South African Referral Hospital
Melanoma
 5 min.

 Published on 17/03/2025 |  Original article (Abstract)  | Tod Bianca et al. | Journal of Skin Cancer, 2025, 4779587

Acral melanoma (AM), defined here as melanoma arising on the palm, sole, or nail apparatus, is a unique subtype of malignant melanoma. It differs from other melanoma subtypes in terms of epidemiology, clinical and pathological features, prognosis, and molecular characteristics [1–3]. Our knowledge...

A case of subcutaneous metastatic malignant melanoma of the left medial ankle: a case report and review of literature
Melanoma
 3 min.

 Published on 10/03/2025 |  Original article (Abstract)  | Workman Lauren et al. | Journal of Medical Case Reports 2024; 18(1): 647

When a patient presents with malignant melanoma without evidence of an epidermal component, the differential diagnosis may include melanoma of unknown primary (MUP) which can present as palpable lymphadenopathy or as a solitary dermal lesion. As defined by Das Gupta, MUP involves presence of melanoma...

Evidence of 18F-FDG Utility in Rare Case of Metastatic Anal Melanoma With Prolonged Survival
Melanoma
 1 min.

 Published on 03/03/2025 |  Original article (Abstract)  | Ranes, Jennifer Marie Catherine MD et al. | Clinical Nuclear Medicine 2025; 50(3): 257-60

A 43-year-old woman presented with an anorectal mass at which time excision was performed, and biopsy revealed anorectal mucosal melanoma (AM), anal subtype. Postexcision, F-FDG PET/CT identified residual melanoma, confirmed on biopsy. Recurrence was monitored every 3 months using F-FDG, which identified...

Blue Nevus‐Like Metastatic Melanoma in a Patient With Primary Lentigo Maligna Melanoma
Melanoma
 2 min.

 Published on 24/02/2025 |  Original article (Abstract)  | Kristen Fernandez et al. | Journal of Cutaneous Pathology 2025; AOP: 10.1111/cup.14765

Metastatic melanoma carries a poor prognosis, with a 5‐year survival rate around 10%, and distant metastases having a less favorable prognosis than local spread or recurrence [1]. The skin is the most common site involved by metastatic melanoma, observed in approximately in 50%–60% of cases [2]....