Skin cancer is classified into two main types: melanoma and non-melanoma skin cancer (NMSC). Over the past several decades, epidemiologic studies have demonstrated an increased incidence of both non-melanoma and melanoma skin cancers [1]. Early diagnosis and treatment of these cancers represent major...
Acral melanoma (AM), defined here as melanoma arising on the palm, sole, or nail apparatus, is a unique subtype of malignant melanoma. It differs from other melanoma subtypes in terms of epidemiology, clinical and pathological features, prognosis, and molecular characteristics [1–3]. Our knowledge...
When a patient presents with malignant melanoma without evidence of an epidermal component, the differential diagnosis may include melanoma of unknown primary (MUP) which can present as palpable lymphadenopathy or as a solitary dermal lesion. As defined by Das Gupta, MUP involves presence of melanoma...
A 43-year-old woman presented with an anorectal mass at which time excision was performed, and biopsy revealed anorectal mucosal melanoma (AM), anal subtype. Postexcision, F-FDG PET/CT identified residual melanoma, confirmed on biopsy. Recurrence was monitored every 3 months using F-FDG, which identified...
Metastatic melanoma carries a poor prognosis, with a 5‐year survival rate around 10%, and distant metastases having a less favorable prognosis than local spread or recurrence [1]. The skin is the most common site involved by metastatic melanoma, observed in approximately in 50%–60% of cases [2]....