
Choroidal melanoma arising from an optic disk melanocytoma is rare but has been previously described at an incidence of 1-2%. Evaluating these cases for pathology and genetics is relevant for determining metastatic risk. Methods: Case report....

Immunotherapy has reshaped melanoma treatment, yet the majority of patients fail to respond or develop resistance. Nerve growth factor receptor (NGFR/p75NTR/CD271) has been linked to melanoma aggressiveness and therapeutic resistance, but the underlying mechanisms remain unclear. Here, we demonstrate...

The overall incidence of pituitary apoplexy among patients with pituitary adenoma ranges from 0.6% to 7.0%, although many cases likely go undiagnosed. Several precipitating factors have been identified, and a small number of case reports have suggested an association between immune checkpoint inhibitors...

Data are available on reasonable request. The data underlying this article are available in the article and in its online supplementary material. More specific data in this article cannot be shared due to the privacy of individuals that participated in the study. Further information and requests for...