MelanomaArchives
The FGL1-LAG-3 axis attenuates melanoma-induced cachexia in mice
Melanoma 1 min.
Cachexia is a debilitating condition characterized by the wasting of adipose and skeletal muscle tissues, resulting in significant weight loss and frailty. It is responsible for 20% of cancer-related mortalities. Despite its clinical significance, the precise mechanisms underlying cachexia remain inadequately...
Refining adjuvant therapy options in patients with stage II melanoma
Melanoma 1 min.
Patients with stage II melanoma have multiple adjuvant therapy options in national guidelines. We evaluated management strategies to better define treatment in this heterogeneous population. Using the National Cancer Database (2010–2021), we identified patients with pathological stage IIA-IIC cutaneous...
The integrated 31-gene expression profile test identifies low-risk patients with cutaneous melanoma who can forego the SLNB procedure: results from a prospective, multicenter trial
Melanoma 1 min.
Prospectively confirm use of the integrated 31-gene expression profile test (i31-SLNB) in patients with cutaneous melanoma to predict sentinel lymph node biopsy (SLNB) positivity and assess recurrence rates in those considered low risk by i31-SLNB who did not have an SLNB. Patients with T1–T4 tumors...
Systemic cardiac migration of perfluorocarbon liquid following unsuccessful endoresection of choroidal melanoma: a case report
Melanoma 1 min.
Choroidal melanoma (CM) is the most common intraocular malignant tumor in adults, with a high rate of metastasis and mortality. This study reports a case of systemic cardiac migration of perfluorocarbon liquid (PFCL) following an unsuccessful endoresection of CM. A 61-year-old woman underwent gamma knife...
Machine learning-based prognostic prediction for cutaneous malignant melanoma patient survival
Melanoma 1 min.
Cutaneous malignant melanoma (CMM) is a highly malignant tumor that necessitates early diagnosis and precise survival prediction. The development of accurate prognostic models is essential for improving patient survival. This retrospective study analyzed data from 5979 CMM patients in the SEER database...
Histopathological characteristics of secondary enucleation after iodide-125 plaque radiotherapy in Chinese patients with uveal melanoma
Melanoma 6 min.
Data are available on reasonable request. The data underlying this article are available in the article and in its online supplementary material. More specific data in this article cannot be shared due to the privacy of individuals that participated in the study. Further information and requests for...
