MelanomaArchives
Investigation of oral bromelain supplementation on the healing of skin flap reconstruction after Mohs micrographic surgery (MMS) for non-melanoma skin cancers (NMSCs)
Melanoma 1 min.
Non-melanoma skin cancers (NMSCs) are the most common malignancies and Mohs micrographic surgery (MMS) with flap reconstruction is the treatment of choice. This study aims to investigate the effect of bromelain on the healing of skin flaps following MMS for NMSCs. Methods: In a single-center, parallel-group,...
Efficacy of intraoperative topical Sapylin (OK-432) for preventing lymph leakage following inguinal lymph node dissection in melanoma: a retrospective cohort study
Melanoma 1 min.
To evaluate whether intraoperative topical Sapylin (OK-432) reduces postoperative lymphatic leakage after inguinal lymph node dissection (ILND) in melanoma patients. Methods: This retrospective study included 105 melanoma patients who underwent unilateral ILND (2022-2025). The study group (n = 51) received...
The FGL1-LAG-3 axis attenuates melanoma-induced cachexia in mice
Melanoma 1 min.
Cachexia is a debilitating condition characterized by the wasting of adipose and skeletal muscle tissues, resulting in significant weight loss and frailty. It is responsible for 20% of cancer-related mortalities. Despite its clinical significance, the precise mechanisms underlying cachexia remain inadequately...
Refining adjuvant therapy options in patients with stage II melanoma
Melanoma 1 min.
Patients with stage II melanoma have multiple adjuvant therapy options in national guidelines. We evaluated management strategies to better define treatment in this heterogeneous population. Using the National Cancer Database (2010–2021), we identified patients with pathological stage IIA-IIC cutaneous...
Histopathological characteristics of secondary enucleation after iodide-125 plaque radiotherapy in Chinese patients with uveal melanoma
Melanoma 6 min.
Data are available on reasonable request. The data underlying this article are available in the article and in its online supplementary material. More specific data in this article cannot be shared due to the privacy of individuals that participated in the study. Further information and requests for...
