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Targeting ferroptosis in melanoma: cancer therapeutics
Melanoma
 9 min.

 Published on 09/06/2025 |  Original article (Full-text)  | Khorsandi Khatereh et al. | Cell Communication and Signaling 2023; 21(1): 337

Melanoma is the most invasive skin cancer, and metastatic melanoma has the highest risk of death with a median survival rate of nearly 6 months [1]. Melanoma prevalence is significantly rising all around the world [2, 3]. Specialized pigment cells are known as melanocytes, which are found in...

Efficacy and safety of cancer vaccine therapy in malignant melanoma: a systematic review
Melanoma
 24 min.

 Published on 02/06/2025 |  Original article (Full-text)  | Takeshi Seta   et al. | International Journal of Clinical Oncology 2025; 30(6): 1080-97

Malignant melanoma is a cancer arising from melanocytes in the skin and mucous membranes. It is the most common and most aggressive type of skin cancer [1]. Worldwide, an estimated 324,635 people were diagnosed with malignant melanoma in 2020 [2]. It is characterized by early lymphatic and hematogenous...

Integration of graph neural networks and transcriptomics analysis identify key pathways and gene signature for immunotherapy response and prognosis of skin melanoma
Melanoma
 9 min.

 Published on 26/05/2025 |  Original article (Full-text)  | Ye Maodong et al. | BMC Cancer 2025; 25(1): 648

Skin melanoma, originating from melanocytes within skin tissue, accounts for over 90% of skin tumor-related fatalities [1, 2–3]. Presently, a variety of treatment strategies have been developed for skin melanoma, including surgical resection [4, 5], chemotherapy [6, 7], targeted therapy (BRAF and...

Patterns and trends in melanoma mortality in Spain (1999-2022)
Melanoma
 5 min.

 Published on 19/05/2025 |  Original article (Full-text)  | Lucía Cayuela   et al. | Clinical and Translational Oncology 2024; 27(5): 2339-46

Melanoma, a highly aggressive form of skin cancer, poses a significant global health challenge [1]. Primarily driven by ultraviolet radiation exposure, its incidence continues to rise despite increased sun protection efforts [2]. This concerning trend is evident worldwide, including Spain [3]. Understanding...