Melanoma, originating from melanocytes in the skin’s outer layer, is an aggressive form of cancer. It is known for its rapid spread and resistance to therapy, leading to a high fatality rate [1]. While the five-year survival rate for early-stage melanoma is nearly 100%, this figure significantly...
Malignant melanoma (MM) arises from the pigment cells of the skin and is a rare form of cutaneous cancer. Although the annual incidence of melanoma in Japan has been reported to be 1-2 patients/100,000 [1, 2], MM-related mortalities are close to half the cutaneous cancer deaths because of its aggressiveness...
Despite its low incidence, melanoma is one of the most aggressive skin cancers, accounting for nearly 90% of all skin malignant tumor deaths [1]. Early primary melanoma patients can achieve a good prognosis after surgical resection [2]. However, advanced metastatic melanoma presents a significant challenge...
Malignant melanoma arises from the uncontrolled proliferation of malignant melanocytes and accounts for 1.7% of all cancer diagnoses [1,2,3]. This malignancy is a life-threatening form of skin cancer and it is known by its aggressiveness [1, 3,4,5]. There are four main types as cutaneous melanoma, acral...