MelanomaArchives
Genetic and Epigenetic Changes in Melanoma Progression: A TCGA-based Study.
Melanoma 1 min.
We aimed to investigate molecular mechanisms affecting melanoma progression by comparing genetic/epigenetic features between melanomas of different Breslow thickness and stage using TCGA (The Cancer Genome Atlas) data. The TCGA, Firehose Legacy, melanoma data set was utilized on the cBioPortal website....
Enhancing radiotherapy for melanoma: the promise of high-Z metal nanoparticles in radiosensitization
Melanoma 1 min.
Melanoma is a type of skin cancer that can be challenging to treat, especially in advanced stages. Radiotherapy is one of the main treatment modalities for melanoma, but its efficacy can be limited due to the radioresistance of melanoma cells. Recently, there has been growing interest in using high-Z...
Immunotherapy and delivery systems for melanoma
Melanoma 1 min.
Melanoma is a highly malignant tumor of melanocyte origin that is prone to early metastasis and has a very poor prognosis. Early melanoma treatment modalities are mainly surgical, and treatment strategies for advanced or metastatic melanoma contain chemotherapy, radiotherapy, targeted therapy and immunotherapy....
Spectral CT imaging for assessment of metastases in melanoma patients: multi-reader evaluation
Melanoma 5 min.
Malignant melanoma is a common oncological disease in the western world with a significant increase in incidence over the last decades [1, 2]. It is an aggressive malignancy which may metastasize throughout the body, including tissues which are rarely affected by metastases of other oncological diseases...
Giant malignant melanoma of the upper limb: a case report and review of the literature
Melanoma 4 min.
Malignant melanoma (MM) is an aggressive form of skin cancer that originates from the melanocytes [1]. While typically presenting as small, pigmented lesions, rare cases of giant melanoma, defined as tumors > 10 cm in diameter, have been reported [2, 3]. These cases pose unique clinical challenges...
