MelanomaArchives
Targeting ferroptosis in melanoma: cancer therapeutics
Melanoma 9 min.
Melanoma is the most invasive skin cancer, and metastatic melanoma has the highest risk of death with a median survival rate of nearly 6 months [1]. Melanoma prevalence is significantly rising all around the world [2, 3]. Specialized pigment cells are known as melanocytes, which are found in...
Efficacy and safety of cancer vaccine therapy in malignant melanoma: a systematic review
Melanoma 24 min.
Malignant melanoma is a cancer arising from melanocytes in the skin and mucous membranes. It is the most common and most aggressive type of skin cancer [1]. Worldwide, an estimated 324,635 people were diagnosed with malignant melanoma in 2020 [2]. It is characterized by early lymphatic and hematogenous...
Integration of graph neural networks and transcriptomics analysis identify key pathways and gene signature for immunotherapy response and prognosis of skin melanoma
Melanoma 9 min.
Skin melanoma, originating from melanocytes within skin tissue, accounts for over 90% of skin tumor-related fatalities [1, 2–3]. Presently, a variety of treatment strategies have been developed for skin melanoma, including surgical resection [4, 5], chemotherapy [6, 7], targeted therapy (BRAF and...
Patterns and trends in melanoma mortality in Spain (1999-2022)
Melanoma 5 min.
Melanoma, a highly aggressive form of skin cancer, poses a significant global health challenge [1]. Primarily driven by ultraviolet radiation exposure, its incidence continues to rise despite increased sun protection efforts [2]. This concerning trend is evident worldwide, including Spain [3]. Understanding...
