Others Infectious Diseases: Archives News of the month
Novel insights into the molecular mechanisms of sepsis-associated acute kidney injury: an integrative study of GBP2, PSMB8, PSMB9 genes and immune microenvironment characteristics
Others Infectious Diseases 7 min.
SA-AKI constitutes a sophisticated microcirculatory dysfunction that entails a considerable risk of advancing to chronic kidney disease (CKD) and renal failure, ultimately giving rise to notable morbidity and mortality burdens. Recent clinical statistics reveal that the incidence of SA-AKI in intensive...
Haemoadsorption to remove inflammatory mediators in sepsis: past, present, and future
Others Infectious Diseases 8 min.
Haemoadsorption may improve outcomes of patients with sepsis by attenuating the inflammatory response, but current evidence does not support their routine use, therefore selective adsorption therapy that may enable removal of specific mediators represents a novel approach. Future studies in this area...
Bilateral retinal artery occlusion as the initial presentation of infectious endocarditis: a case report
Others Infectious Diseases 2 min.
Central retinal artery occlusion (CRAO) is a rare but devastating disorder that typically presents as sudden painless loss of vision in the involved eye. The obstruction of blood flow to the central retinal artery (CRA) has several etiologies, but the most common etiology is embolism from an atherosclerotic...
CTSO and HLA-DQA1 as biomarkers in sepsis-associated ARDS: insights from RNA sequencing and immune infiltration analysis
Others Infectious Diseases 8 min.
Septicemia, a life-threatening condition, stands as a prominent cause of mortality, primarily resulting from severe impairment of the host's anti-infective defenses [1, 2–3]. As already demonstrated by several studies, anaerobic glycolysis of immune cells can give rise to septicemia [4, 5, 6–7]....
Volume kinetics in a translational porcine model of stabilized sepsis with fluid accumulation
Others Infectious Diseases 6 min.
The ROSE framework (Resuscitation, Optimization, Stabilization, and Evacuation) describes successive stages of fluid administration [1] in critically ill patients. This conceptualization acknowledges the fluid accumulation syndrome or fluid overload, notoriously associated with poor outcomes [2]. The...
