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Prevalence and Associated Explanatory Factors for Augmented Renal Clearance in Early Sepsis: Single-Center, Retrospective PICU Cohort in China, 2022-2023.

 Published on 10/07/2025 |  Original article (Full-text)  | Xu, Lili BS et al. | Pediatric Critical Care Medicine. Volume 26(6).

We aimed to 1) evaluate the prevalence of augmented renal clearance (ARC) in pediatric sepsis patients; 2) analyze potential explanatory factors associated with ARC out of hemodynamic, oxygenation, and inflammatory parameters; and 3) assess ARC outcomes. DESIGN: Retrospective, single-center, cohort from...

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Exploring the antimicrobial efficacy of Manuka honey against multidrug-resistant and extensively drug-resistant Salmonella Typhi causing septicemia in Pakistan

 Published on 03/07/2025 |  Original article (Full-text)  | Iqra Bashir et al. | Future Microbiology 2024; 19(16): 1377-87

To determine the efficacy of manuka honey against multidrug-resistant (MDR) and extensively drug-resistant (XDR) clinical strains of SalmonellaTyphi. Materials & methods: Clinical isolates were processed using the Bactec blood culture system, identification and...

The mRNA vaccine, a swift warhead against a moving infectious disease target

 Published on 26/06/2025 |  Original article (Full-text)  | Sheema Mir et al. | Expert Review of Vaccines 2024; 23(1): 336-48

The rapid development of mRNA vaccines against SARS-CoV-2 has revolutionized vaccinology, offering hope for swift responses to emerging infectious diseases. Initially met with skepticism, mRNA vaccines have proven effective and safe, reducing vaccine hesitancy amid the evolving COVID-19 pandemic. The...

Clinical features and outcomes of infective endocarditis in persons experiencing homelessness

 Published on 19/06/2025 |  Original article (Full-text)  | Teng Torrance et al. | Infectious Diseases of Poverty 2025; 14(1): 48

Infective endocarditis (IE) is an infection of the endocardium that results in significant morbidity and mortality [1]. IE can cause substantial damage to the body, resulting in severe multi-organ system damage and death with a mortality rate approaching 30% at 30 days [2]. Standard treatment entails...