
To investigate the value of combined procalcitonin (PCT) and interleukin-6 (IL-6) assessment for early risk stratification in sepsis. This retrospective cohort study enrolled 375 patients with sepsis stratified by the first Sequential Organ Failure Assessment (SOFA) score within 24 h of admission....

Switching to oral therapy has become an option for treating infective endocarditis (IE) in well-selected patients. This study aimed to assess its effectiveness in real-life settings, including patients who would not have been eligible under current guidelines based on the POET trial results. Methods:...

Graphical Significant MV dysfunction often requires surgical MV repair or surgical MV replacement with a biological or mechanical prosthesis. Over a follow-up of 10 year, first-time IE occurrence was significantly more frequent in patients who had previously undergone MV replacement compared with those...

The World Health Organization (WHO) classifies a burn as damage to the skin or other organic tissue that is primarily due to heat, radiation, radioactivity, electricity, friction, or contact with chemicals [1]. Burn injuries not only inflict enduring physical harm, but also significantly affect psychological...

Among 598 infective endocarditis (IE) episodes, follow-up blood cultures within 14 days of antimicrobial treatment completion were performed in 135 (23%) cases and detected only 2 (1.5%) recurrences. This strategy failed to identify 8 (6%) additional IE recurrences diagnosed between days 15 and 120,...