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Early prognostic value of combined procalcitonin and interleukin-6 in sepsis: a retrospective cohort study

 Published on 11/06/2026 |  Original article (Full-text)  | Xuefang Xia et al. | Biomarkers in Medicine 2026; aop:10.1080/17520363.2026.2682836

To investigate the value of combined procalcitonin (PCT) and interleukin-6 (IL-6) assessment for early risk stratification in sepsis. This retrospective cohort study enrolled 375 patients with sepsis stratified by the first Sequential Organ Failure Assessment (SOFA) score within 24 h of admission....

Should We Extend the Use of Oral Antibiotics in Infective Endocarditis? The ENDO-ORAL Study

 Published on 04/06/2026 |  Original article (Full-text)  | Benoit Rallet et al. | Clinical infectious diseases. Volume 82(3).

Switching to oral therapy has become an option for treating infective endocarditis (IE) in well-selected patients. This study aimed to assess its effectiveness in real-life settings, including patients who would not have been eligible under current guidelines based on the POET trial results. Methods:...

Unveiling the risk of infective endocarditis after mitral valve replacement and mitral valve repair

 Published on 28/05/2026 |  Original article (Full-text)  | Daniele Giacoppo | European Heart Journal. Volume 46(36).

Graphical Significant MV dysfunction often requires surgical MV repair or surgical MV replacement with a biological or mechanical prosthesis. Over a follow-up of 10 year, first-time IE occurrence was significantly more frequent in patients who had previously undergone MV replacement compared with those...

Association between ABO blood groups and sepsis risk in severe burns: a retrospective cohort study

 Published on 21/05/2026 |  Original article (Full-text)  | Yu Hengkai et al. | BMC Infectious Diseases 2025; 26(1): 282

The World Health Organization (WHO) classifies a burn as damage to the skin or other organic tissue that is primarily due to heat, radiation, radioactivity, electricity, friction, or contact with chemicals [1]. Burn injuries not only inflict enduring physical harm, but also significantly affect psychological...

Rethinking the Routine: Are Repeat Blood Cultures Necessary After Completion of Infective Endocarditis Treatment?

 Published on 14/05/2026 |  Original article (Full-text)  | Jean Regina et al. | Clinical infectious diseases. Volume 82(3).

Among 598 infective endocarditis (IE) episodes, follow-up blood cultures within 14 days of antimicrobial treatment completion were performed in 135 (23%) cases and detected only 2 (1.5%) recurrences. This strategy failed to identify 8 (6%) additional IE recurrences diagnosed between days 15 and 120,...