Others Infectious DiseasesArchives
Reduced plasma levels of Copine 5 correlate with sepsis-induced vascular leakage and mortality in human patients and a murine sepsis model
Others Infectious Diseases 9 min.
Sepsis is characterized as life-threatening organ dysfunction caused by a dysregulated host response to infection with concurrent hyper-inflammation and immunosuppression [1]. Although the clinical managements with early adequate antimicrobial medication to control infection and the immediate hemodynamic...
Identification of protein biomarkers to differentiate between gram-negative and gram-positive infections in adults suspected of sepsis
Others Infectious Diseases 6 min.
Sepsis is a life-threatening condition resulting from a dysregulated response to infection, with the risk of rapid progression to septic shock and potentially fatal outcomes without timely recognition and treatment [1]. Bacterial infection is the major cause of sepsis [1], with both gram-negative and...
FPR1-dependent Pro-inflammatory Ccl4high monocytes/macrophages drive and predict sepsis-induced acute lung injury
Others Infectious Diseases 13 min.
Sepsis is a life-threatening multiorgan dysfunction caused by a disordered host response to infection. It carries high morbidity and mortality rates. The lung is particularly vulnerable to sepsis-induced damage [1, 2]. Sepsis-induced acute lung injury (ALI) can rapidly progress to acute respiratory distress...
Metagenomic next-generation sequencing (mNGS) guides targeted antibiotic therapy and reduces mortality in sepsis: a propensity-matched retrospective cohort study
Others Infectious Diseases 4 min.
Sepsis is a significant public health problem and a life-threatening condition characterized by organ dysfunction due to a dysregulated host response to infection [1, 2]. It is one of the leading causes of death in the intensive care unit (ICU) [3], with over 5 million sepsis-related deaths annually...
