Others Infectious DiseasesArchives
Rethinking the Routine: Are Repeat Blood Cultures Necessary After Completion of Infective Endocarditis Treatment?
Others Infectious Diseases 1 min.
Among 598 infective endocarditis (IE) episodes, follow-up blood cultures within 14 days of antimicrobial treatment completion were performed in 135 (23%) cases and detected only 2 (1.5%) recurrences. This strategy failed to identify 8 (6%) additional IE recurrences diagnosed between days 15 and 120,...
Frequency of Antibiotic Overtreatment and Associated Harms in Patients Presenting With Suspected Sepsis to the Emergency Department: A Retrospective Cohort Study
Others Infectious Diseases 1 min.
Treatment guidelines recommend rapidly treating all patients with suspected sepsis with broad-spectrum antibiotics. This may contribute to antibiotic overuse. We quantified the incidence of antibiotic overtreatment and possible antibiotic-associated harms among patients with suspected sepsis. Methods:...
Infective endocarditis and spondylodiscitis-impact of sequence of surgical therapy on survival and recurrence rate
Others Infectious Diseases 1 min.
To date, there are no standardized treatment algorithms or recommendations for patients with infective endocarditis (IE) and concomitant spondylodiscitis (SD). Therefore, our aim was to analyse whether the sequence of surgical treatment of IE and SD has an impact on postoperative outcome and to identify...
Current status of immunomodulatory therapies in adult sepsis patients: where do we stand?
Others Infectious Diseases 1 min.
Despite advances, sepsis remains a leading cause of morbidity and mortality worldwide. Dysregulated host responses are known to characterize sepsis, and while numerous clinical trials using immunomodulatory strategies have been attempted, most fail to show benefit. An important reason for their failure...
Surgical Implications of the 2023 ESC Endocarditis Guidelines Endorsed by EACTS: Bridging Guidelines and Practice
Others Infectious Diseases 1 min.
Role of the multidisciplinary "Endocarditis Team": All patients with complicated infective endocarditis (IE) should be managed by a specialized Endocarditis Team to improve diagnosis, optimize treatment, and enhance outcomes (Figure 1). Indications for surgery: The main surgical indications for IE include...
