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Resolution pharmacology and the treatment of infectious diseases
Others Infectious Diseases
 11 min.

 Published on 22/02/2024 |  Original article (Full-text)  | Vivian Vasconcelos Costa et al. | British Journal of Pharmacology 2024; AOP: 10.1111/bph.16323

Inflammation is elicited by the host in response to microbes, and is believed to be essential for protection against infection. This process starts through the activation of innate immune cells expressing pattern recognition receptors (PRRs), which recognize molecular patterns expressed by microorganisms...

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Developing an early warning system for detecting sepsis in patients with trauma
Others Infectious Diseases
 4 min.

 Published on 15/02/2024 |  Original article (Full-text)  | Kucun Guo et al. | International wound journal 2024; 21(1): 14652

There are nearly 5.8 million deaths from trauma worldwide each year. Severe trauma is the sixth leading cause of death in the world, and mortality from severe trauma increases significantly with age. In patients aged over 65 who have a previous history and complications, the mortality from severe...

Gut microbiota composition and changes in patients with sepsis: potential markers for predicting survival
Others Infectious Diseases
 5 min.

 Published on 08/02/2024 |  Original article (Full-text)  | Luan Feiyu et al. | BMC Microbiology 2024; 24(1): 45

There are 100 trillion parasitic microorganisms in the human gastrointestinal (GI) tract [1], including bacteria, viruses, fungi, archaea, and protozoa, which are collectively termed the gut microbiota [2]. Research has long focused on the pathogenicity of gut microbiota, but new studies suggest that...

Deep evolutionary fusion neural network: a new prediction standard for infectious disease incidence rates
Others Infectious Diseases
 5 min.

 Published on 01/02/2024 |  Original article (Full-text)  | Yao Tianhua et al. | BMC Bioinformatics 2023; 25(1): 38

The incidence of infectious diseases has always been a public health problem worthy of attention and can cause very large social, economic and health burdens [1]. Using data on the numbers of infectious cases to predict the trends of infectious diseases can provide a focus and direction for the actual...

Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction: a systematic review and meta-analysis
Others Infectious Diseases
 5 min.

 Published on 25/01/2024 |  Original article (Full-text)  | Kuklin Vladimir et al. | Critical Care 2023; 28(1): 12

Sepsis is defined by the Third International Consensus as “life-threatening organ dysfunction caused by a dysregulated host response to infection” [1], and is comprised of a complex, intertwined interaction of inflammation, endothelial dysfunction, capillary leak, and a spectrum of pathologic...