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Incidence and risk factor of sepsis in patients with severe community-acquired pneumonia: a Chinese, single-center, retrospective study

 Published on 08/05/2025 |  Original article (Full-text)  | Wang Xinyu et al. | BMC Infectious Diseases 2025; 25(1): 649

Community-acquired pneumonia (CAP) is defined as an acute infection of the pulmonary parenchyma acquired in the community (outside the hospital setting) and remains a major public health concern [1]. With approximately 6 million cases reported annually in the United States and over 1.5 million individuals...

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Assessment of the diagnostic significance of pentraxin-3 in conjunction with procalcitonin (PCT) and C-reactive protein (CRP) for neonatal sepsis

 Published on 01/05/2025 |  Original article (Full-text)  | Jin Yan et al. | BMC Infectious Diseases 2025; 25(1): 401

Neonatal sepsis is a systemic inflammatory response triggered by pathogenic microorganisms entering the bloodstream of neonates through various routes [1]. It represents a critical condition observed in neonates following infections [2]. Recent population-level studies over the past two decades suggest...

AngioVac-assisted management of histoplasma capsulatum endocarditis in a bioprosthetic aortic valve: challenges and outcomes

 Published on 24/04/2025 |  Original article (Full-text)  | Qafisheh Qutaiba et al. | Journal of Cardiothoracic Surgery 2025; 20(1): 213

Infective endocarditis is a serious condition involving infection of the endocardium or heart valves, which can lead to significant morbidity and mortality if untreated [1]. Causes vary and include bacterial, fungal, and other etiologies. One of the fungal causes is Histoplasma capsulatum, an endemic...

The prognostic role of vegetation size in pediatric infective endocarditis: a retrospective study using decision curve and dose-response analysis

 Published on 17/04/2025 |  Original article (Full-text)  | Luo Yonghan et al. | BMC Infectious Diseases 2025; 25(1): 511

Infective endocarditis (IE) is an inflammation of the endocardium caused by microbial infection, with vegetations often affecting heart valves, leading to varying degrees of valvular dysfunction and potentially resulting in heart failure [1]. The in-hospital mortality rate for IE reaches as high as 24.2–30%...

Leptin and Iinterlukin-6 relationship and influence of mortality in sepsis

 Published on 10/04/2025 |  Original article (Full-text)  | Tsai Yi-Hsuan et al. | BMC Infectious Diseases 2025; 25(1): 460

Sepsis is a severe and heterogeneous disease that makes life life-threatening [1]. Precious studies found many risk factors associated with septic mortality such as comorbidity [2], poor nutrition [3], infection source [4], diagnosis timing [5], abnormal clinical data [6], and immunocompromised [7]....