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Surgical Implications of the 2023 ESC Endocarditis Guidelines Endorsed by EACTS: Bridging Guidelines and Practice

 Published on 16/04/2026 |  Original article (Full-text)  | Manuela de la Cuesta et al. | European journal of cardio-thoracic surgery. Volume 67(7).

Role of the multidisciplinary "Endocarditis Team": All patients with complicated infective endocarditis (IE) should be managed by a specialized Endocarditis Team to improve diagnosis, optimize treatment, and enhance outcomes (Figure 1). Indications for surgery: The main surgical indications for IE include...

Conservative versus surgical treatment of patients with infective endocarditis after transcatheter aortic valve implantation: a systematic review and meta-analysis

 Published on 09/04/2026 |  Original article (Full-text)  | N Pyrpyris et al. | European Heart Journal Supplement. Volume 28(Supplement 3).

Infective endocarditis after transcatheter aortic valve implantation (TAVI-IE) is a rare but serious complication associated with high morbidity and mortality. Strategies for managing TAVI-IE vary significantly, with the optimal therapeutic approach remaining a subject of debate. Therefore, the aim of...

Revising Sepsis Definitions to Better Target and Tailor Sepsis Care

 Published on 02/04/2026 |  Original article (Full-text)  | Michael Klompas et al. | Clinical infectious diseases. Volume 80(6).

How we define sepsis has significant implications for clinical care, quality improvement, and regulatory policies. Current sepsis criteria identify heterogenous patients that vary widely in their clinical syndromes, triggering pathogens, and prognoses; one-third have viral or non-infectious processes...

Reassessing Procalcitonin-Guided Antibiotic Therapy in Critically Ill Patients With Sepsis: Lessons From the ADAPT-Sepsis Trial

 Published on 26/03/2026 |  Original article (Full-text)  | Simran Gupta et al. | Clinical infectious diseases. Volume 82(3).

Randomized trials of procalcitonin-guided algorithms to discontinue antibiotics in critically ill patients with sepsis report reduced antibiotic duration and possible mortality benefit. However, open-label trial designs, inconsistent algorithm adherence, and unclear stewardship practices have limited...

Non-bacterial thrombotic endocarditis in cancer

 Published on 19/03/2026 |  Original article (Full-text)  | Francois Deharo et al. | European Heart Journal. Volume 47(9).