
Graphical Significant MV dysfunction often requires surgical MV repair or surgical MV replacement with a biological or mechanical prosthesis. Over a follow-up of 10 year, first-time IE occurrence was significantly more frequent in patients who had previously undergone MV replacement compared with those...

The World Health Organization (WHO) classifies a burn as damage to the skin or other organic tissue that is primarily due to heat, radiation, radioactivity, electricity, friction, or contact with chemicals [1]. Burn injuries not only inflict enduring physical harm, but also significantly affect psychological...

Among 598 infective endocarditis (IE) episodes, follow-up blood cultures within 14 days of antimicrobial treatment completion were performed in 135 (23%) cases and detected only 2 (1.5%) recurrences. This strategy failed to identify 8 (6%) additional IE recurrences diagnosed between days 15 and 120,...

Treatment guidelines recommend rapidly treating all patients with suspected sepsis with broad-spectrum antibiotics. This may contribute to antibiotic overuse. We quantified the incidence of antibiotic overtreatment and possible antibiotic-associated harms among patients with suspected sepsis. Methods:...

To date, there are no standardized treatment algorithms or recommendations for patients with infective endocarditis (IE) and concomitant spondylodiscitis (SD). Therefore, our aim was to analyse whether the sequence of surgical treatment of IE and SD has an impact on postoperative outcome and to identify...