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Translocator Protein Deficiency Promotes Splenomegaly with Extramedullary Hematopoiesis after Sepsis.

 Published on 30/07/2026 |  Original article (Full-text)  | Kikutani, Kazuya et al. | Shock. Volume 66(2).

The translocator protein 18 kDa (TSPO) is expressed in immune cells such as macrophages and hematopoietic progenitors and is involved in modulating innate immune responses. However, a role of TSPO in postsepsis immune dysregulation remains unclear, particularly in the spleen as one of the major immune...

Endocarditis caused by Aerococcus urinae: a case report and review of literature

 Published on 23/07/2026 |  Original article (Full-text)  | Giovanni, Gobbo et al. | Journal of Medical Case Reports. Volume 20(1).

Infective endocarditis is an infectious disease associated with high morbidity and mortality; incidence has been increasing in recent decades. Most common causes of infective endocarditis are Staphylococcus aureus, Streptococci, and Enterococci. Bacteria of the genus Aerococcus...

Effect of vitamin D administration on sepsis score and C-reactive protein (CRP) levels in preterm infants with neonatal sepsis: a randomized controlled trial

 Published on 16/07/2026 |  Original article (Full-text)  | Wijaya, Michelle Angelica et al. | BMC Pediatrics. Volume 26(1).

Neonatal sepsis remains a leading cause of mortality in preterm infants. While Vitamin D possesses immunomodulatory properties, evidence for its adjuvant role in sepsis is limited. This study evaluated the efficacy of two Vitamin D doses (400 IU vs. 800 IU) on clinical sepsis scores and C-reactive protein...

Echocardiographically occult nonbacterial thrombotic endocarditis with tumor cell-containing valvular vegetations in metastatic breast cancer

 Published on 09/07/2026 |  Original article (Full-text)  | Charaya, Kristina et al. | Cardio-Oncology. Volume 12(1).

Nonbacterial thrombotic endocarditis (NBTE) is an uncommon but important cause of systemic arterial embolism, most often occurring in advanced malignancy. Diagnosis is frequently difficult because vegetations may be small, transient, or not visualized on echocardiography, which may delay recognition. Case...