Liver Diseases: Archives News of the month
PD-1 inhibitors improve the efficacy of transcatheter arterial chemoembolization combined with apatinib in advanced hepatocellular carcinoma: a meta-analysis and trial sequential analysis
Liver Diseases 7 min.
Hepatocellular carcinoma (HCC) is one of the most prevalent malignant neoplasms globally, with China accounting for nearly half of the global patient population [1, 2]. This malignancy is characterized by a high mortality rate and poor patient prognosis, with the majority of patients diagnosed in the...
The pringle maneuver for Budd-Chiari syndrome-related orthotopic liver transplantation: an experience from a large referral center
Liver Diseases 4 min.
Budd-Chiari syndrome (BCS) is a potentially life-threatening disease defined as the obstruction of the hepatic venous outflow tract in the absence of cardiac or pericardial pathology [1]. In patients with progressive BCS that results in liver cirrhosis due to chronic congestion, orthotopic liver transplantation...
Interaction between the liver transcriptome and gut microbiota in mice during Toxoplasma gondii infection as identified by integrated transcriptomic and microbiome analysis
Liver Diseases 8 min.
Toxoplasma gondii is a widespread protozoan parasite that is distributed globally and capable of infecting almost all warm-blood animals, including humans [1]. Humans primarily become infected by T. gondii through the consumption of raw or undercooked meat containing tissue cysts...
A novel c.59 C > T variant of the HSD17B10 gene as a possible cause of the neonatal form of HSD10 mitochondrial disease with hepatic dysfunction: a case report and review of the literature
Liver Diseases 4 min.
HSD10 mitochondrial disease (OMIM 300438) was originally described as 2-methyl-3-hydroxybutyryl-l CoA dehydrogenase deficiency (MHBDD), a rare X-linked recessive genetic disorder. The multifunctional 17β-HSD10 protein is encoded by the HSD17B10 gene. The protein is widely distributed in...
Association between liver fibrosis’s noninvasive scores and retinal imaging changes: insights from NHANES
Liver Diseases 4 min.
Retinopathy is a common eye disease characterized by damage to the retinal microvasculature [1]. It is the leading cause of blindness worldwide [2], and is closely associated with diseases such as diabetes, hypertension and chronic kidney disease [3, 4]. Evidence suggests that retinopathy not only represents...
