Iron is an essential micronutrient involved in DNA synthesis, and mitochondrial and protein function [1]. Within heme, iron ensures oxygen exchange but these electron transfer properties are responsible for iron excess toxicity: free iron promotes Fenton’s reaction, resulting in the production...
Metabolic-associated fatty liver disease (MAFLD) has emerged as the most prevalent chronic liver disease globally, affecting an estimated 25% of the adult population [1]. MAFLD can advance to cirrhosis and hepatocellular carcinoma, representing a leading cause of liver-related mortality worldwide. Due...
In June 2023, an international panel of experts utilised a Delphi consensus process to propose the term metabolic dysfunction-associated steatotic liver disease (MASLD) as a replacement for the previously used term nonalcoholic fatty liver disease (NAFLD) [1, 2]. The diagnostic criteria for MASLD include...
Orthotopic liver transplantation (OLT) is the only curative treatment for patients suffering from acute or chronic liver failure. Several factors such as diabetes mellitus, age, preoperative anemia, transfusion of packed red blood cells, postoperative acute kidney injury (AKI), and peritonitis have been...
Metabolic dysfunction-associated steatotic liver disease (MASLD), the latest term for steatotic liver disease associated with metabolic syndrome, is a prevalent condition currently estimated to affect up to one third of the global adult population worldwide [1]. MASLD is a common disease in which...