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A clinical predictive score of high liver iron content in metabolic hyperferritinemia: a retrospective cohort pilot study
Liver Diseases
 4 min.

 Published on 08/05/2025 |  Original article (Full-text)  | Boughzala Mohamed Lotfi et al. | BMC Gastroenterology 2025; 25(1): 331

Iron is an essential micronutrient involved in DNA synthesis, and mitochondrial and protein function [1]. Within heme, iron ensures oxygen exchange but these electron transfer properties are responsible for iron excess toxicity: free iron promotes Fenton’s reaction, resulting in the production...

Meat and fish consumption, genetic risk and risk of severe metabolic-associated fatty liver disease: a prospective cohort of 487,875 individuals
Liver Diseases
 6 min.

 Published on 01/05/2025 |  Original article (Full-text)  | Wang Jianjin et al. | Nutrition Journal 2025; 24(1): 65

Metabolic-associated fatty liver disease (MAFLD) has emerged as the most prevalent chronic liver disease globally, affecting an estimated 25% of the adult population [1]. MAFLD can advance to cirrhosis and hepatocellular carcinoma, representing a leading cause of liver-related mortality worldwide. Due...

Associations between non-insulin-based insulin resistance surrogate markers and liver-related outcomes in metabolic dysfunction-associated steatotic liver disease: a nationwide cohort study in South Korea
Liver Diseases
 6 min.

 Published on 24/04/2025 |  Original article (Full-text)  | Moon Sang Yi et al. | BMC Gastroenterology 2025; 25(1): 274

In June 2023, an international panel of experts utilised a Delphi consensus process to propose the term metabolic dysfunction-associated steatotic liver disease (MASLD) as a replacement for the previously used term nonalcoholic fatty liver disease (NAFLD) [1, 2]. The diagnostic criteria for MASLD include...

The association of perioperative serum albumin concentrations with outcome after deceased donor liver transplantation
Liver Diseases
 5 min.

 Published on 17/04/2025 |  Original article (Full-text)  | Lichtenegger Paul et al. | BMC Anesthesiology 2025; 25(1): 178

Orthotopic liver transplantation (OLT) is the only curative treatment for patients suffering from acute or chronic liver failure. Several factors such as diabetes mellitus, age, preoperative anemia, transfusion of packed red blood cells, postoperative acute kidney injury (AKI), and peritonitis have been...

The role of Triglyceride Glucose-Waist Circumference (TyG_WC) in predicting metabolic dysfunction-associated steatotic liver disease among individuals with hyperuricemia
Liver Diseases
 5 min.

 Published on 10/04/2025 |  Original article (Full-text)  | Wang Qian-Qian et al. | BMC Gastroenterology 2025; 25(1): 220

Metabolic dysfunction-associated steatotic liver disease (MASLD), the latest term for steatotic liver disease associated with metabolic syndrome, is a prevalent condition currently estimated to affect up to one third of the global adult population worldwide [1]. MASLD is a common disease in which...