Rheumatoid Arthritis (RA): Archives News of the month
Comparative analysis of clinical profile, therapeutic management, and clinical prognosis of patients with seropositive or seronegative rheumatoid arthritis following the introduction of a first targeted therapy in a real-life setting
Rheumatoid Arthritis (RA) 8 min.
Rheumatoid arthritis (RA) is a multifactorial autoimmune and inflammatory disease, influenced by genetic, environmental, and hormonal factors. The interaction of these factors leads to an uncontrolled immune response and production of autoantibodies, notably rheumatoid factors (RF) and anticitrullinated...
A theory of change for patient-initiated follow-up care in rheumatoid arthritis
Rheumatoid Arthritis (RA) 8 min.
Early diagnosis, targeted treatment, and regular monitoring are essential to improve long-term outcomes for individuals with rheumatoid arthritis (RA) [1, 2]. The current standard of care for rheumatology in Canada involves routine follow-up appointments every 6–12 months, irrespective of disease...
Predicting rheumatoid arthritis progression from seronegative undifferentiated arthritis using machine learning: a deep learning model trained on the KURAMA cohort and externally validated with the ANSWER cohort
Rheumatoid Arthritis (RA) 5 min.
Rheumatoid arthritis (RA) poses a significant burden on patients, presenting a wide range of clinical manifestations, including joint arthritis and extra-articular symptoms, which can lead to substantial morbidity and disability if left untreated or inadequately managed [1, 2]. Early diagnosis and treatment...
Mendelian randomization and mediation analysis reveal the role of immune cell subsets in the causal pathways between blood cell perturbation responses and rheumatoid arthritis
Rheumatoid Arthritis (RA) 6 min.
Rheumatoid arthritis (RA) is a complex autoimmune disease primarily characterized by chronic joint inflammation, often accompanied by systemic immune dysregulation [1, 2]. While the precise etiology of RA remains unclear, studies suggest that genetic predisposition, environmental factors, and abnormal...
“As long as you learn to adapt”–a longitudinal mixed-methods study exploring the first decade with rheumatoid arthritis
Rheumatoid Arthritis (RA) 7 min.
In rheumatoid arthritis (RA), routines for early diagnosis and early treatment have been available for decades. These include Disease-Modifying Anti-Rheumatic Drugs (DMARDs), with the goal of remission or low disease activity [1]. From a longitudinal perspective, even though the effects of early interventions...
