Log in  First Connection?

Adrenal Glands Diseases: Archives News of the month

Massive pheochromocytoma causing adrenal crisis during surgery: a case report and review of the literature

 Published on 20/03/2025 |  Original article (Abstract)  | Zeng Jiyu et al. | Journal of Medical Case Reports 2025; 19(1): 111

Pheochromocytoma is an infrequent neuroendocrine neoplasm arising from the adrenal medulla, distinguished by the overproduction of catecholamines, such as epinephrine and norepinephrine. It has an incidence rate of approximately 2–8 per million individuals [1]. The clinical presentation of pheochromocytoma...

Atypical clinical presentation of oncocytic adrenocortical carcinoma with decompensated metabolic syndrome and psychotic outbreak

 Published on 13/03/2025 |  Original article (Abstract)  | Bastien Picut et al. | BMJ case reports 2025; 18(3): e262948

The fortuitous discovery of an adrenal mass is defined as an adrenal incidentaloma, which is very common, affecting 3%–10% of the global population, with most cases presenting as adrenal adenomas.1 In contrast, adrenocortical carcinoma (ACC) is a rare disease, with an estimated incidence of 0.7–2...

Attenuation of Hypertension and protection of vascular inflammation in hyperaldosteronism: GPER1 as potential therapeutic candidate when MR antagonist is less satisfying?

 Published on 06/03/2025 |  Original article (Abstract)  | Yulian Lai et al. | Endocrine 2024; 87(3): 1276-84

Primary aldosteronism(PA) is a prevalent underlying cause of hypertension and a significant risk factor for cardiovascular and renal morbidity [1, 2]. It is characterized by autonomous secretion of aldosterone (ALDO) from the adrenal glands, resulting in low levels of renin. ALDO is a hormone that modulates...

Oncological Management of Adrenocortical Carcinoma: An Update and Critical Review

 Published on 27/02/2025 |  Original article (Abstract)  | Nicholas P. Rowell   et al. | Oncology and Therapy 2025; aop: 10.1007/s40487-025-00327-5

Adrenocortical carcinoma (ACC) is a rare cancer, with an annual incidence of approximately one case per million population in the USA and Europe [1, 2]. Median age at diagnosis is 55 years, with a slight female preponderance, and approximately one-quarter of patients present with metastatic disease...

Women’s response regarding timing of genital surgery in congenital adrenal hyperplasia

 Published on 20/02/2025 |  Original article (Abstract)  | Henrik Falhammar   et al. | Endocrine 2024; 87(2): 830-5

Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting the steroid synthesis. The far most common cause of CAH is 21-hydroxylase deficiency (21OHD) [1]. In 21OHD cortisol and aldosterone concentrations are often low. In contrast, androgen and steroid precursor concentrations...