Pheochromocytoma is an infrequent neuroendocrine neoplasm arising from the adrenal medulla, distinguished by the overproduction of catecholamines, such as epinephrine and norepinephrine. It has an incidence rate of approximately 2–8 per million individuals [1]. The clinical presentation of pheochromocytoma...
The fortuitous discovery of an adrenal mass is defined as an adrenal incidentaloma, which is very common, affecting 3%–10% of the global population, with most cases presenting as adrenal adenomas.1 In contrast, adrenocortical carcinoma (ACC) is a rare disease, with an estimated incidence of 0.7–2...
Primary aldosteronism(PA) is a prevalent underlying cause of hypertension and a significant risk factor for cardiovascular and renal morbidity [1, 2]. It is characterized by autonomous secretion of aldosterone (ALDO) from the adrenal glands, resulting in low levels of renin. ALDO is a hormone that modulates...
Adrenocortical carcinoma (ACC) is a rare cancer, with an annual incidence of approximately one case per million population in the USA and Europe [1, 2]. Median age at diagnosis is 55 years, with a slight female preponderance, and approximately one-quarter of patients present with metastatic disease...
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting the steroid synthesis. The far most common cause of CAH is 21-hydroxylase deficiency (21OHD) [1]. In 21OHD cortisol and aldosterone concentrations are often low. In contrast, androgen and steroid precursor concentrations...