Adrenal Glands DiseasesArchives
Exploring the FAP-Targeted Therapeutics for Adrenocortical Carcinoma: Choosing the Right Track
Adrenal Glands Diseases 1 min.
Metastatic or recurrent adrenocortical carcinoma is a potentially lethal malignancy, presenting significant challenges in disease management owing to absence of effective systemic treatments. Significantly diminished survival rates necessitate rapid identification of specific molecules for the development...
Pheochromocytoma in a patient with heterotaxy syndrome: a case report
Adrenal Glands Diseases 4 min.
In a normal human body, internal organs are generally arranged in a specific pattern called situs solitus, where the heart is on the left side of the chest, the liver is on the right, and other organs are positioned predictably. Heterotaxy syndrome is a rare congenital condition characterized by the...
Massive pheochromocytoma causing adrenal crisis during surgery: a case report and review of the literature
Adrenal Glands Diseases 4 min.
Pheochromocytoma is an infrequent neuroendocrine neoplasm arising from the adrenal medulla, distinguished by the overproduction of catecholamines, such as epinephrine and norepinephrine. It has an incidence rate of approximately 2–8 per million individuals [1]. The clinical presentation of pheochromocytoma...
Atypical clinical presentation of oncocytic adrenocortical carcinoma with decompensated metabolic syndrome and psychotic outbreak
Adrenal Glands Diseases 3 min.
The fortuitous discovery of an adrenal mass is defined as an adrenal incidentaloma, which is very common, affecting 3%–10% of the global population, with most cases presenting as adrenal adenomas.1 In contrast, adrenocortical carcinoma (ACC) is a rare disease, with an estimated incidence of 0.7–2...
Attenuation of Hypertension and protection of vascular inflammation in hyperaldosteronism: GPER1 as potential therapeutic candidate when MR antagonist is less satisfying?
Adrenal Glands Diseases 4 min.
Primary aldosteronism(PA) is a prevalent underlying cause of hypertension and a significant risk factor for cardiovascular and renal morbidity [1, 2]. It is characterized by autonomous secretion of aldosterone (ALDO) from the adrenal glands, resulting in low levels of renin. ALDO is a hormone that modulates...
