Tuberculosis: Archives News of the month
Direct detection from sputum for drug-resistant Mycobacterium tuberculosis using a CRISPR-Cas14a-based approach
Tuberculosis 6 min.
It is estimated that approximately 400,000 new patients were diagnosed with rifampicin-resistant tuberculosis (RR-TB) or multi-drug resistant tuberculosis (MDR-TB) in 2023. However, the global treatment coverage rate for MDR/RR-TB in 2023 was merely 44% (175,923/400,000) [1]. The emergence of resistance...
Treatment completion and safety profile of once-weekly 3HP regimen for tuberculosis preventive treatment in children and adolescents: a systematic review
Tuberculosis 4 min.
Despite being a preventable disease, tuberculosis (TB) remains a significant global public health challenge and a leading cause of morbidity and mortality among children and adolescents [1]. According to the World Health Organization (WHO), approximately 1.3 million children and adolescents were...
Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases
Tuberculosis 10 min.
Tuberculosis disease (TBD), caused by Mycobacterium tuberculosis (Mtb), in the last four years, was the second cause of death from a single infectious agent, after SARS-CoV-2 [1, 2]. The reported global number of people newly diagnosed with TBD was 7.5 million in 2022. This is the highest...
Risk factors for rifampicin-susceptible and isoniazid-resistant tuberculosis in adult patients with type 2 diabetes mellitus in Nanjing
Tuberculosis 4 min.
China is a country with a high burden of tuberculosis and drug-resistant tuberculosis, as well as a high incidence of diabetes, accounting for a quarter of the world’s adult diabetes patients [1, 2]. One study has shown the risk of developing tuberculosis in diabetic patients was more than three...
Post coronavirus-disease-vaccination immune reconstitution inflammatory syndrome in tuberculosis treatment: a case report
Tuberculosis 2 min.
Tuberculosis (TB) immune reconstitution inflammatory syndrome (IRIS) is an abnormal, excessive immune response against living or dead Mycobacterium tuberculosis. Paradoxical worsening of tuberculosis has been described after introduction of antituberculosis drugs. We report on an unusual presentation...
