Cardiac surgery-associated acute kidney injury (CS-AKI) is a common postoperative complication with an incidence of 20–50%, resulting in increased in-hospital morbidity, mortality and healthcare costs [1, 2]. The diagnosis of acute kidney injury (AKI) is based on increased serum creatinine (sCr),...
Mechanical ventilation (MV) is associated with the risk of acute kidney injury (AKI) in critically ill patients. Recent studies have shown that patients undergoing MV have an approximately three-fold higher risk of developing AKI than those not requiring ventilatory support [1]. A complete understanding...
Vesicoureteral reflux (VUR) after pediatric kidney transplantation (KT) is a frequent urological complication that occurs in 19–60% of patients who have undergone an anti-reflux procedure [1, 2, 3–4]. VUR of the transplanted kidney is usually not a problem in the absence of urinary tract...
The kidney glomerulus is the anatomical site where filtration defects are particularly localized. It harbors multiple cell types including glomerular podocytes, mesangial cells, and fenestrated endothelial cells. Glomerular podocytes and capillary endothelial cells are separated by a thick glomerular...
Cardiovascular disease remains the leading cause of death worldwide [1, 2]. The escalating prevalence of cardiovascular diseases, with a particular emphasis on acute ST-segment-elevation myocardial infarction (STEMI), is imposing an unprecedented strain on healthcare systems worldwide, presenting a significant...