Log in  First Connection?

Acute & Chronic Kidney InjuryArchives

Early osmotherapy exposure and subsequent incident acute kidney injury in neurocritical care patients: a MIMIC-IV retrospective cohort study

 Published on 29/07/2026 |  Original article (Full-text)  | Du, Shenshen et al. | Journal of Intensive Care. Volume 14(1).

Osmotherapy is frequently used in neurocritical care to manage cerebral edema and intracranial hypertension. However, its association with subsequent new-onset acute kidney injury (AKI), and whether early serum sodium or chloride burden materially attenuates this association, remain uncertain. Methods:...