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Acute & Chronic Kidney InjuryArchives

Remote ischemic per-conditioning did not modulate kidney Klotho expression in acute kidney injury induced by renal ischemia/reperfusion injury

 Published on 19/11/2025 |  Original article (Full-text)  | Afshari Afsoon et al. | BMC Nephrology 2025; 26(1): 637

Renal ischemia-reperfusion injury (I/RI) is a major reason for acute kidney injury (AKI) that occurs due to renal transplantation, trauma, sepsis, and some vascular surgery [1]. Although various studies have been performed to understand the causes and molecular mechanisms of renal I/RI, it remains a...

A Strategic Roadmap to Support Communication on and Acceptance of Surrogate Endpoints: The REnal Surrogacy accEpTance in Chronic Kidney Disease (RESET CKD) Collaboration

 Published on 12/11/2025 |  Original article (Full-text)  | Garcia Sanchez Juan José et al. | Advances in Therapy 2025; 42(11): 5727-41

The development of innovative and effective treatments remains a priority [1, 2], especially for chronic and progressive diseases associated with high morbidity and mortality despite current therapies [3, 4, 5–6]. Demonstrating the definitive benefit of new interventions on patient-relevant final...

The association between potassium level during the anhepatic stage of orthotopic liver transplantation and postoperative acute kidney injury: an exploratory study

 Published on 05/11/2025 |  Original article (Full-text)  | Gao Qian et al. | BMC Nephrology 2025; 26(1): 602

Liver transplantation (LT) has emerged as the definitive and preferred modality for hepatic replacement in end-stage liver disease patients [1]. Despite the escalating success rates of the procedure due to medical technological innovations, the postoperative outcomes, both in the short and long term,...

Energy drink-induced acute kidney injury: a case report and review of the literature

 Published on 29/10/2025 |  Original article (Full-text)  | Murt Ahmet et al. | Journal of Medical Case Reports 2025; 19(1): 522

Acute kidney injury (AKI) is an important health problem with an increasing incidence [1]. The etiology should be defined and relevant treatment should be started swiftly [2]. Etiologies of AKI may be different for hospital-acquired (HA) and community-acquired (CA) AKIs. Infections, volume loss, glomerular...