Acute & Chronic Kidney InjuryArchives
Impact of CRRT on graft outcomes in kidney transplantation from deceased donors with severe acute kidney injury
Kidney transplantation (KT) from deceased donors (DDs) with acute kidney injury (AKI) has become increasingly common due to organ shortages. While AKI has traditionally raised concerns about graft quality, recent studies suggest that kidneys from donors with AKI can provide acceptable outcomes [1, 2–3]....
Discovery of a resistant cohort to acute kidney injury: insights from patients with septic shock
Acute kidney injury (AKI) is a common complication of critical illness, increasing the risk of morbidity and mortality [1, 2–3], yet there remain no direct therapeutic options. Sepsis-associated AKI occurs in 40–50% of patients with sepsis [1] and increases mortality three to five-fold [4]....
Lessons learned from the outbreak: the use of fomepizole in children with acute kidney injury due to ethylene glycol/diethylene glycol poisoning
Ethylene glycol (EG) and diethylene glycol (DEG) intoxication are defined as > 20 mg/dL EG/DEG in plasma, which may cause severe morbidity and mortality. The intoxication of both alcohols results from the metabolism of EG/DEG via alcohol dehydrogenase (ADH) enzymes and their conversion...
Inflammatory parameters in the prediction of sepsis-induced acute kidney injury: a case-control study
According to the Sepsis-3 definition, the presence of infection-induced organ dysfunction is a necessary condition for establishing the diagnosis of sepsis [1, 2]. Consequently, recently published studies have focused on identifying reliable, rapid, easily accessible, and cost-effective predictors of...
