Acute & Chronic Kidney InjuryArchives
A comparative analysis of drug-induced kidney injury adverse reactions between cyclosporine and tacrolimus based on the FAERS database
Nephrotoxicity is the inability of the kidneys to properly detoxify and excrete drugs and toxic chemicals due to destruction or injury caused by endogenous or exogenous toxicants [1]. It is characterized by elevated serum creatinine and urea, decreased GFR (glomerular filtration) rate, and may be accompanied...
The predictive value of renal vascular resistance index and serum biomarkers for sepsis-associated acute kidney injury: a retrospective study
Sepsis, a critical and often deadly condition arising from an abnormal defensive response to infection, represents a substantial load on healthcare systems globally [1, 2–3]. It is a primary cause of morbidity and fatalities, with an approximate annual incidence of approximately 31.5 million...
Does combining urine sediment examination to renal cell arrest and damage biomarkers improve prediction of progression and mortality of sepsis associated acute kidney injury?
Acute kidney injury (AKI) is a frequent medical condition among hospitalized patients. AKI occurs in 31 to 65% of patients with septic shock and is linked to higher mortality and consumption of health care resources [1, 2]. A definition for sepsis-associated AKI (SA-AKI) was developed by the Acute Disease...
The association between pan-immune-inflammation value with mortality in critically ill patients with sepsis-associated acute kidney injury
Acute kidney injury (AKI) and sepsis are common disease, imposing a significant economic burden on healthcare, with direct medical costs of approximately $10 billion and $20 billion annually, respectively [1, 2]. It is notable that the combination of AKI and sepsis frequently occurs in the...
Risk analysis and mediation analysis of stress hyperglycemia ratio and all-cause mortality in patients with acute kidney injury
Acute kidney injury (AKI) represents a major global public health challenge, affecting millions of patients worldwide and characterized by a rapid deterioration of renal function over a short period of time [1]. Approximately 10–15% of hospitalized patients experience AKI, with the incidence reaching...
