Acute & Chronic Kidney InjuryArchives
Immunoinflammatory biomarkers for sepsis-associated acute kidney injury: a multicenter prospective cohort study
Immune dysregulation is central to sepsis-related organ injury, yet standard clinical indicators show limited predictive value for sepsis-associated acute kidney injury (SA-AKI) in older adults(aged ≥ 65 years). This study evaluated whether immuno-inflammatory biomarkers improve early prediction of...
Gut microbiota dysbiosis in intensive care unit patients with acute kidney injury: insights from 16S sequencing and mediation analysis
The gut-kidney axis is critical in acute kidney injury (AKI) pathophysiology, but its specific characteristics in intensive care unit (ICU) patients remain unclear. This study aimed to investigate compositional and functional alterations of gut microbiota in AKI patients. Methods: Patients were divided...
Short- and long-term outcomes of elderly patients with acute kidney injury to acute kidney disease
Acute kidney disease (AKD) describes acute or subacute renal damage and/or loss of kidney function between 7 and 90 days after AKI initiation. Because there are few reports on AKD in older patients, the present study evaluated the risk factors and outcomes of AKD in older patients. Methods: A retrospective,...
Prognostic value of modified KDIGO staging for acute kidney injury in neonates: a prospective observational study in a level IIIB NICU
Acute kidney injury in neonates is increasingly recognised as a significant contributor to morbidity and mortality in neonatal intensive care units particularly in low- and middle-income countries where diagnostic limitations and variable definitions have historically hindered accurate reporting and...
