Pediatric Transplant: Archives News of the month
Pulmonary function testing in pediatric allogeneic stem cell transplant recipients to monitor for Bronchiolitis obliterans syndrome: a systematic review
Pediatric Transplant 5 min.
Allogeneic hematopoietic stem cell transplantation (aHSCT) is an important modality for treating hematologic malignancies as well as many non-malignant conditions in children and young adults. Pulmonary complications are relatively common after pediatric aHSCT and cause significant morbidity and mortality...
Risk of cellular or antibody-mediated rejection in pediatric kidney transplant recipients with BK polyomavirus replication—an international CERTAIN registry study
Pediatric Transplant 9 min.
In kidney transplant recipients, reactivation of BK polyomavirus (BKPyV) replication is a common consequence of immunosuppressive therapy, which can progress to BKPyV-associated nephropathy (BKPyVAN), and ultimately to graft loss [1]. Additionally, primary BKPyV infection can occur in BKPyV-naïve...
Multidisciplinary approach to optimizing long-term outcomes in pediatric kidney transplant recipients: multifaceted needs, risk assessment strategies, and potential interventions
Pediatric Transplant 7 min.
The multifaceted demands of pediatric kidney transplant care are well recognized. To optimize outcomes of pediatric kidney transplant recipients, the American Society of Pediatric Nephrology recommends delivering care through a multidisciplinary paradigm [1], which often encompasses a pediatric nephrologist,...
Follow-up biopsies with microvascular inflammation and persistent donor specific antibodies identify ongoing rejection in pediatric kidney transplant recipients
Pediatric Transplant 6 min.
Despite advances in immunosuppressive therapies, development of acute allograft rejection remains a common complication in pediatric and adolescent kidney transplant recipients (KTR). Predisposing risk factors for development of acute rejection are multifactorial and can include inadequate immunosuppression,...
Obesity and metabolic syndrome in a diverse pediatric kidney transplant population: which anthropometric measure best predicts arterial stiffness?
Pediatric Transplant 6 min.
Pediatric kidney transplant recipients are known to experience a heightened risk for cardiovascular (CV) disease [1]. Obesity and metabolic syndrome are highly prevalent among transplant recipients and are key factors that accelerate the process of arterial stiffening, further contributing to increased...
