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Inherited metabolic diseases are a potent risk factor for cytomegalovirus infection in pediatric living donor liver transplantation

 Published on 17/06/2026 |  Original article (Full-text)  | Ushijima Kentaro et al. | BMC Infectious Diseases 2025; 25(1): 97

Cytomegalovirus (CMV) disease is a common infection following solid organ transplantation, posing significant challenges in clinical management due to its association with both morbidity and, in some cases, mortality. Beyond its immediate effects, CMV contributes to a range of short-term and long-term...

Hemorrhagic cystitis in pediatric severe aplastic anemia undergoing haploidentical hematopoietic stem cell transplantation: incidence, risk factors and outcomes

 Published on 10/06/2026 |  Original article (Full-text)  | Cui Kai et al. | BMC Pediatrics 2025; 25(1): 234

Severe aplastic anemia (SAA) is an uncommon and life-threatening disease, marked by bone marrow failure and pancytopenia [1]. Immunosuppressive therapy (IST) and matched sibling donor hematopoietic stem cell transplantation (MSD-HSCT) are the preferred recommended treatments [2]. However, IST is ineffective...

Clinical and molecular genetic characteristics of pediatric PFIC3 patients: three novel variants and prognosis for parental liver transplantation

 Published on 03/06/2026 |  Original article (Full-text)  | Hu Jiqiang et al. | Orphanet Journal of Rare Diseases 2025; 20(1): 164

PFIC3 is a rare recessive liver disorder that falls within the category of Familial Intrahepatic Cholestasis (PFIC). PFIC is a spectrum of inherited disorders of intrahepatic cholestasis, arising from various genetic mutations. The global incidence of PFIC is estimated to be between 1 in 100,000 and...

Characterization of emergency department visits in pediatric patients within first year of liver transplantation: ten years experience in tertiary care center

 Published on 27/05/2026 |  Original article (Full-text)  | Elmokattaf Reem et al. | BMC Emergency Medicine 2025; 25(1): 76

Liver transplant is one of the major advances in medicine and one of the most performed surgeries in transplant. In the Kingdom of Saudi Arabia, the first liver transplant was performed in 1991. However, pediatric liver transplant didn’t start until 1997, trailed by adult living donor transplant...