Pediatric TransplantArchives
Case series of kidney transplantation in two pediatric recipients with rare genetic diseases and intellectual disability
Pediatric Transplant 4 min.
Kidney transplantation is the treatment of choice for end-stage kidney disease (ESKD) in children, due to lower mortality rates and fewer cognitive and learning impairments when compared to long-term kidney replacement therapy [1]. Kidney transplantation in pediatric patients also has the benefit of...
Inherited metabolic diseases are a potent risk factor for cytomegalovirus infection in pediatric living donor liver transplantation
Pediatric Transplant 5 min.
Cytomegalovirus (CMV) disease is a common infection following solid organ transplantation, posing significant challenges in clinical management due to its association with both morbidity and, in some cases, mortality. Beyond its immediate effects, CMV contributes to a range of short-term and long-term...
Hemorrhagic cystitis in pediatric severe aplastic anemia undergoing haploidentical hematopoietic stem cell transplantation: incidence, risk factors and outcomes
Pediatric Transplant 4 min.
Severe aplastic anemia (SAA) is an uncommon and life-threatening disease, marked by bone marrow failure and pancytopenia [1]. Immunosuppressive therapy (IST) and matched sibling donor hematopoietic stem cell transplantation (MSD-HSCT) are the preferred recommended treatments [2]. However, IST is ineffective...
Clinical and molecular genetic characteristics of pediatric PFIC3 patients: three novel variants and prognosis for parental liver transplantation
Pediatric Transplant 5 min.
PFIC3 is a rare recessive liver disorder that falls within the category of Familial Intrahepatic Cholestasis (PFIC). PFIC is a spectrum of inherited disorders of intrahepatic cholestasis, arising from various genetic mutations. The global incidence of PFIC is estimated to be between 1 in 100,000 and...
