Pediatric TransplantArchives
Development and prospective evaluation of a machine learning model to predict vomiting among pediatric cancer and hematopoietic cell transplant patients
Pediatric Transplant 5 min.
Vomiting is one of the most common symptoms experienced by pediatric cancer and hematopoietic cell transplant (HCT) patients, with substantial negative impacts on quality of life [1, 2]. Vomiting can reduce oral intake, worsen nutritional status, lead to hospitalization and increase healthcare costs...
A cohort of allogeneic hematopoietic stem cell transplantation for pediatric rare diseases (allo-HSCT-PRD): design and preliminary results
Pediatric Transplant 4 min.
According to the China Rare Disease Definition Study Report 2021, rare diseases are defined as those with an incidence rate of fewer than 1 in 10,000 live births, a prevalence rate below 1 in 10,000, or a total affected population not exceeding 140,000 individuals within the national population. Orphanet,...
Concomitant Azole Initiation Decreases Time to Stable Goal Sirolimus Concentrations in Pediatric Allogeneic Transplant Recipients.
Pediatric Transplant 1 min.
Variability of sirolimus pharmacokinetics, often compounded by interactions with azole antifungal therapy, leads to concentrations outside the goal range and increased risk of related complications. We assessed the time to initial attainment of stable goal sirolimus concentrations in patients who either...
Evolving strategies to optimize immunization and protection of pediatric transplantation recipients.
Pediatric Transplant 1 min.
Indications for pediatric solid organ (SOT) and hematopoietic cell transplantation (HCT) have expanded concurrently with a repertoire of new biologics and transplant-related immunosuppression regimens, leading to a growing population of immunocompromised children who remain at risk for infections. Immunization...
Liver transplantation for pediatric liver malignancies.
Pediatric Transplant 1 min.
In the last few decades, collaboration between international pediatric oncology groups has resulted in significant improvement in survival after liver transplantation (LT) for pediatric liver tumors, and LT has become the accepted standard of care for unresectable pediatric liver tumors-either living...
