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Letermovir for cytomegalovirus prophylaxis in pediatric allogeneic hematopoietic stem cell transplantation: a single-center experience

 Published on 01/07/2026 |  Original article (Full-text)  | Tsai, Pai-Lin et al. | Blood research. Volume 61(1).

Letermovir prophylaxis results in a significantly lower risk of clinically significant cytomegalovirus (CMV) infection in adult hematopoietic stem cell transplant recipients. However, studies supporting its efficacy in pediatric patients are limited. Methods: We retrospectively reviewed the outcomes...

Case series of kidney transplantation in two pediatric recipients with rare genetic diseases and intellectual disability

 Published on 24/06/2026 |  Original article (Full-text)  | Mata Marina et al. | BMC Pediatrics 2024; 24(1): 823

Kidney transplantation is the treatment of choice for end-stage kidney disease (ESKD) in children, due to lower mortality rates and fewer cognitive and learning impairments when compared to long-term kidney replacement therapy [1]. Kidney transplantation in pediatric patients also has the benefit of...

Inherited metabolic diseases are a potent risk factor for cytomegalovirus infection in pediatric living donor liver transplantation

 Published on 17/06/2026 |  Original article (Full-text)  | Ushijima Kentaro et al. | BMC Infectious Diseases 2025; 25(1): 97

Cytomegalovirus (CMV) disease is a common infection following solid organ transplantation, posing significant challenges in clinical management due to its association with both morbidity and, in some cases, mortality. Beyond its immediate effects, CMV contributes to a range of short-term and long-term...

Hemorrhagic cystitis in pediatric severe aplastic anemia undergoing haploidentical hematopoietic stem cell transplantation: incidence, risk factors and outcomes

 Published on 10/06/2026 |  Original article (Full-text)  | Cui Kai et al. | BMC Pediatrics 2025; 25(1): 234

Severe aplastic anemia (SAA) is an uncommon and life-threatening disease, marked by bone marrow failure and pancytopenia [1]. Immunosuppressive therapy (IST) and matched sibling donor hematopoietic stem cell transplantation (MSD-HSCT) are the preferred recommended treatments [2]. However, IST is ineffective...