Pediatric TransplantArchives
Frequency of Culture-proven Bacterial Infection and Radiographic Pneumonia in Pediatric Heart Transplant Recipients.
Pediatric Transplant 1 min.
Infection is a leading cause of death after pediatric heart transplants (PHTs). Understanding of common pathogens is needed to guide testing strategies and empiric antibiotic use. Methods: We conducted a 3-center retrospective study of PHT recipients <=18 years old presenting to cardiology clinics...
Successful Use of Granulocyte Transfusion Therapy as a Bridge to Hematopoietic Stem Cell Transplant in a Child With Aplastic Anemia and Refractory Perirectal Abscess.
Pediatric Transplant 1 min.
This brief report describes the use of adjuvant granulocyte transfusion therapy to successfully treat refractory proctitis with perirectal abscess in a child with very severe aplastic anemia. She was not expected to have imminent neutrophil recovery, which, by current practice guidelines, is a prerequisite...
Examining Different Methods to Assess Busulfan Exposure in Pediatric Hematopoietic Stem Cell Transplant Recipients.
Pediatric Transplant 1 min.
Noncompartmental analysis (NCA) and model-based method (MBM) can be used to estimate the cumulative area under the concentration-time curve (AUCcum) during therapeutic drug monitoring. Understanding predictive differences among these techniques should assist in switching between them and interpreting...
Successful Unmanipulated Haploidentical Hematopoietic Stem Cell Transplant With Post-transplant Cyclophosphamide in a Child With Down Syndrome and Myelodysplastic Syndrome.
Pediatric Transplant 1 min.
Allogeneic hematopoietic stem cell transplant (HSCT) in children with Down syndrome and hematologic malignancies is challenging and is reserved for those who develop relapsed/refractory disease due to concerns regarding transplant-related mortality. Haploidentical HSCT, although performed in limited...
