Pediatric TransplantArchives
Hematopoietic Stem Cell Transplantation Achieves Sustained Remission in Pediatric RAS-Associated Autoimmune Lymphoproliferative Disorder with Life-Threatening Complications: a Single-Center Case Series and Literature Review
Pediatric Transplant 1 min.
RAS-associated autoimmune lymphoproliferative disorder (RALD) is a rare disease caused by somatic mutations in KRAS or NRAS genes and is characterized by hepatosplenomegaly, cytopenia, and autoimmune manifestations. Current conventional therapies often yield only transient remission....
Letermovir for cytomegalovirus prophylaxis in pediatric allogeneic hematopoietic stem cell transplantation: a single-center experience
Pediatric Transplant 1 min.
Letermovir prophylaxis results in a significantly lower risk of clinically significant cytomegalovirus (CMV) infection in adult hematopoietic stem cell transplant recipients. However, studies supporting its efficacy in pediatric patients are limited. Methods: We retrospectively reviewed the outcomes...
Case series of kidney transplantation in two pediatric recipients with rare genetic diseases and intellectual disability
Pediatric Transplant 4 min.
Kidney transplantation is the treatment of choice for end-stage kidney disease (ESKD) in children, due to lower mortality rates and fewer cognitive and learning impairments when compared to long-term kidney replacement therapy [1]. Kidney transplantation in pediatric patients also has the benefit of...
Inherited metabolic diseases are a potent risk factor for cytomegalovirus infection in pediatric living donor liver transplantation
Pediatric Transplant 5 min.
Cytomegalovirus (CMV) disease is a common infection following solid organ transplantation, posing significant challenges in clinical management due to its association with both morbidity and, in some cases, mortality. Beyond its immediate effects, CMV contributes to a range of short-term and long-term...
