Pediatric TransplantArchives
Pediatric bone marrow microenvironment before and after allogeneic hematopoietic stem cell transplantation: a multicenter retrospective study comparing donors and recipients
Pediatric Transplant 5 min.
Hematopoietic stem cell transplantation (HSCT) is a potentially curative therapeutic approach for pediatric patients with hematologic malignancies, erythrocyte disorders, bone marrow failure, severe immunodeficiencies, and certain metabolic diseases [1]. Over the past decade, the implementation of the...
Targeted strategies for pediatric cancer and post-transplant fever: the role of host and pathogen biomarkers.
Pediatric Transplant 1 min.
Host and pathogen biomarkers may lead to improved management of fever in children with cancer and post hematopoietic cell transplant (HCT). This review summarizes current evidence on biomarkers for predicting infections. Recent findings: Host biomarkers show promise for distinguishing between infectious...
Primary hyperoxaluria: insights into its clinical presentation, genetic mutations, and transplantation outcomes in a pediatric population in a tertiary care center
Pediatric Transplant 3 min.
Primary hyperoxaluria (PH) is a rare inherited disorder characterized by oxalate overproduction in blood and urine due to defects in glyoxylate metabolism (see supplementary file 1), leading to recurrent kidney stones, nephrocalcinosis, and progressive kidney damage. Among its three known subtypes, namely...
Development and prospective evaluation of a machine learning model to predict vomiting among pediatric cancer and hematopoietic cell transplant patients
Pediatric Transplant 5 min.
Vomiting is one of the most common symptoms experienced by pediatric cancer and hematopoietic cell transplant (HCT) patients, with substantial negative impacts on quality of life [1, 2]. Vomiting can reduce oral intake, worsen nutritional status, lead to hospitalization and increase healthcare costs...
