Pediatric TransplantArchives
Transforming the treatment of Alpha-Thalassemia: a single-center retrospective study on hematopoietic stem cell transplantation in transfusion-dependent pediatric patients
Pediatric Transplant 4 min.
Alpha-thalassemia affects approximately 5% of the global population, with a notably higher prevalence of 15% in Southeast Asia due to genetic predispositions [1, 2]. Recent global migration patterns have contributed to the spread of α-thalassemia to regions such as Northern Europe and North America...
Expanding pediatric liver transplants: the role of split grafts, allocation policies, and machine perfusion.
Pediatric Transplant 1 min.
Pediatric liver transplant waitlist mortality remains disproportionately high, particularly among infants under one year old. Despite the success of split liver transplantation (SLT) in improving pediatric access to transplants, its utilization remains limited. This review examines barriers to SLT adoption,...
Antimicrobial use in pediatric hematopoietic stem cell transplantation in China: a retrospective multicenter cohort study
Pediatric Transplant 5 min.
Hematopoietic stem cell transplantation (HSCT) is now an important therapeutic intervention for several pediatric hematologic malignancies, as well as non-malignant disorders of the bone marrow failure syndromes, inherited metabolic disorders, and immunodeficiencies. Improvements in transplantation techniques,...
Use of T2Bacteria Panel in Pediatric Hematopoietic Cell Transplant and Cellular Therapy Patients: A Single-Center Experience
Pediatric Transplant 1 min.
We evaluated the use of the T2Bacteria panel for diagnosis of bloodstream infection in pediatric HCT/CT patients. Overall, the panel expedited recognition of bloodstream infections, providing results sooner than Gram stain and final blood culture identification. The T2Bacteria panel contributed to a...
Diagnosis of EBV and HCMV infections in pediatric heart transplant recipients
Pediatric Transplant 3 min.
Infection agents account for one of the leading cause of serious complications and mortality in heart transplantation (HTx) [1]. Among these, viral infections human cytomegalovirus (HCMV) and Epstein–Barr virus (EBV) are considered main threats to heart transplant recipients [2]. The occurrence...
