Epilepsy and Seizures: Archives News of the month
Recognising the neurological burden of onchocerciasis: the need to include onchocerciasis-associated epilepsy in onchocerciasis global health metrics
Epilepsy and Seizures 2 min.
Using data from the 2021 Global Burden of Disease (GBD) study, Zhu and colleagues [1] assessed the prevalence and health burdens of vector-borne parasitic infectious diseases associated with poverty, revealed a statistically significant decrease in the overall burden of onchocerciasis since 1990. The...
Immunological factors in pediatric generalized and focal epilepsy: interplay with anti-seizure medications
Epilepsy and Seizures 4 min.
Epilepsy is a chronic neurological disorder characterized by an enduring predisposition to generate epileptic seizures, affecting approximately 50 million people worldwide, with a higher prevalence in pediatric populations [1, 2]. Pediatric epilepsy encompasses diverse seizure types, including generalized...
Adjunctive Brivaracetam in People with Epilepsy and Intellectual Disability: Evidence from the BRIVAracetam Add-On First Italian netwoRk Study
Epilepsy and Seizures 4 min.
Epilepsies are among the most common chronic disorders of the brain and affect around 55 million people worldwide in absence of geographical, social, or racial boundaries [1]. In people with an intellectual disability, epilepsy is significantly more common than in the general population. Community-based...
Exploring the causal relationship between serum EFNB2 levels and epilepsy: a bidirectional Mendelian randomization and co-localization analysis
Epilepsy and Seizures 6 min.
Epilepsy represents a severe neurological disorder that not only affects neural function but also significantly impedes cognitive and developmental progress, presenting considerable challenges for affected individuals and families globally [1]. Characterized by persistent seizures and profound neurodevelopmental...
Catatonia and Maintenance Electroconvulsive Therapy in a 15-Year-Old Patient With MED13L Haploinsufficiency Syndrome in the Context of Epilepsy Diathesis
Epilepsy and Seizures 2 min.
The MED13L gene encodes a component of the mediator complex, a group of proteins that operates as a transcriptional coactivator for the majority of genes transcribed by RNA polymerase II.1 It is implicated in the initial formation of the heart and brain.1 MED13L haploinsufficiency syndrome has been shown...
