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Real-world efficacy and safety of immune checkpoint blockades in advanced urothelial carcinoma with histologic variant subtypes: the pembroblad study

 Published on 31/07/2026 |  Original article (Full-text)  | Amrane, Karim et al. | Cancer Immunology, Immunotherapy. Volume 75(8).

Histologic variants (HV) of urothelial carcinoma (UC-V) and non-urothelial carcinomas (NUC) of the bladder and urinary tract are aggressive malignancies with poor prognosis and limited response to platinum-based chemotherapy. Despite their biological particularities and distinct immune microenvironments,...

Effectiveness and safety of enfortumab vedotin and pembrolizumab in a real-world patient population with urothelial carcinoma: results from a multi-institutional cohort (GUARDIANS)

 Published on 24/07/2026 |  Original article (Full-text)  | Zschäbitz, Stefanie et al. | Cancer Immunology, Immunotherapy. Volume 75(7).

Enfortumab vedotin plus pembrolizumab (EVP) is the standard first-line treatment for metastatic or locally advanced urothelial carcinoma (m/laUC). Real-world patients frequently present with unfavorable clinical characteristics, raising uncertainty about whether outcomes mirror those of the pivotal EV-302/KEYNOTE-A39...

Single Port Robotic Surgery in Benign Urologic Disease - A Review of Contemporary Applications and Outcomes

 Published on 17/07/2026 |  Original article (Full-text)  | Rabinowitz, Matthew J. et al. | Current Urology Reports. Volume 27(1).

The advent of the Intuitive da Vinci single-port (SP) robotic system represents a pivotal evolution in minimally invasive urologic surgery, offering enhanced dexterity, improved surgical ergonomics, and reduced patient morbidity. This review is designed to provide a comprehensive evaluation of current...

A perioperative multi-modal fusion and deep learning-based prognostic system for upper tract urothelial carcinoma: a multi-institutional study

 Published on 10/07/2026 |  Original article (Full-text)  | Peng, Xiang et al. | Insights into Imaging. Volume 17(1).

Precise perioperative risk stratification for upper tract urothelial carcinoma (UTUC) is essential. We developed a multimodal prognostic model integrating perioperative clinical data, radiomics, and deep learning (DL) features from baseline CT urography to improve survival prediction and guide adjuvant...

In vitro efficacy of ceftazidime/avibactam and cefiderocol against multidrug-resistant Gram-negative uropathogens: insights into ?-lactamase-mediated resistance in clinical isolates

 Published on 03/07/2026 |  Original article (Full-text)  | Ibrahim, Mohamed A. et al. | Future Journal of Pharmaceutical Sciences. Volume 12(1).

Urinary tract infections (UTIs) are among the most common bacterial infections in hospitalized patients, frequently caused by Gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa. The increasing prevalence...