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Urothelium marker UPK2 identifies aggressive colorectal cancers with distinct molecular and histological features

 Published on 06/02/2026 |  Original article (Full-text)  | Äijälä Ville K. et al. | British Journal of Cancer 2026; 134(4): 650-61

Colorectal cancer (CRC) ranks as the second leading cause of cancer-related deaths worldwide [1]. The treatment protocols and prognosis of CRC are influenced by various factors, such as the Tumor-Node-Metastasis classification, mismatch-repair (MMR) status, and tumor morphology [2, 3–4]. Around...

Application of PBL combined with mini-CEX evaluation model in the clinical teaching of urological clinic teaching

 Published on 30/01/2026 |  Original article (Full-text)  | Chen Xin et al. | BMC Medical Education 2025; 26(1): 129

As breakthroughs in medicine and science accelerate global economic growth, medical education is becoming ever more interconnected and globally oriented [1]. Clinical internship constitutes the pivotal step of medical training, during which medical students successfully translate textbook knowledge into...

Characterization and genome analysis of jumbo Escherichia phage UE-S1 and the antibacterial potential of its lysozyme against uropathogenic E. coli

 Published on 23/01/2026 |  Original article (Full-text)  | Niaz Hira et al. | BMC Microbiology 2025; 26(1): 27

E. coli is an opportunistic pathogen that naturally inhabits the gastrointestinal tract, where it generally exists as part of the normal microbiota without causing harm [1]. However, under certain conditions, it can lead to a variety of intestinal and extraintestinal infections, the most common...

State of the art of adjuvant immunotherapy in urothelial cancer: New developments and upcoming changes

 Published on 16/01/2026 |  Original article (Full-text)  | Elisa Tassinari et al. | Human vaccines & immunotherapeutics 2025; 21(1):

In recent years, several clinical trials focused on the potential role of immune-checkpoint inhibitors (ICIs) in the adjuvant treatment of muscle-invasive urothelial cancer (UC). Heretofore, only the anti-programmed death protein 1 (anti-PD1) nivolumab received European Medical Agency (EMA) approval...