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Neoadjuvant immune checkpoint inhibitors for muscle-invasive urothelial carcinoma: a systematic review and meta-analysis

 Published on 20/03/2026 |  Original article (Full-text)  | Ana Luíza Rocha Soares Menegat et al. | Immunotherapy 2026; aop:10.1080/1750743X.2026.2643128

Muscle-invasive urothelial carcinoma (MIUC) represents one-quarter of cancers and carries morbidity and mortality. Although cisplatin neoadjuvant chemotherapy plus radical cystectomy improves survival, patients may be ineligible due to renal dysfunction or comorbidities. Immune checkpoint inhibitors...

Site and number of metastases predict outcomes in avelumab maintenance for advanced UC: results from meet-URO 25

 Published on 13/03/2026 |  Original article (Full-text)  | Roviello Giandomenico et al. | Cancer Immunology, Immunotherapy 2026; 75(3): 79

Urothelial carcinoma (UC) is the most common histological subtype of bladder cancer and other malignancies arising from the urinary tract [1]. While many cases are diagnosed at an early and potentially curable stage, a substantial proportion of patients will eventually develop locally advanced or metastatic...

Bacterial uropathogens, associated factors, and ESBL-producing gram-negative isolates in diabetic patients at Debre Markos comprehensive specialized hospital, Ethiopia

 Published on 06/03/2026 |  Original article (Full-text)  | Mihret Yeshye et al. | BMC Infectious Diseases 2026; 26(1): 378

Non-communicable diseases are becoming a global threat that lead to a high rate of morbidity and mortality. Diabetes mellitus(DM) is one of the most prevalent long-lasting, non-communicable, and endocrine system disorder [1]. The 2017 International Diabetics Federation estimated that 451 million (8.4%)...

The impact of the Sudan conflict on urological surgical training: a national study of challenges, adaptations, and trainee-led pathways to resilience

 Published on 27/02/2026 |  Original article (Full-text)  | Sabil Moaaz Mohammed Osman et al. | BMC Medical Education 2026; 26(1): 309

The destruction of hospitals and the targeting of healthcare workers in armed conflict represent grave atrocities that rightly capture global attention [1]. However, a more insidious and structurally devastating consequence is the severe disruption of a nation’s medical education system—the...