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Emerging Neisseria meningitidis ST-1466 and ST-11026 as urogenital pathogens in China

 Published on 07/11/2025 |  Original article (Full-text)  | Zhu Zhe et al. | BMC Infectious Diseases 2025; 25(1): 1447

Neisseria meningitidis, a Gram-negative coccus commonly colonizing the nasopharynx of humans, is a well-known cause of severe invasive meningococcal disease (IMD), primarily manifests as meningococcal sepsis and meningitis [1]. The incidence of IMD was low worldwide, but it varied significantly...

Effect of early intubation on patient-centered outcomes in urosepsis: a retrospective multicenter cohort study

 Published on 01/11/2025 |  Original article (Full-text)  | Suga Masafumi et al. | Journal of Intensive Care 2025; 13(1): 58

While the overall incidence of sepsis has declined, there has been a notable rise in severe urinary tract infections and urosepsis [1], with correspondingly poor outcomes and complex management requirements [2], including intubation and mechanical ventilation (MV). In patients receiving MV, the timing...

Study on changes in urinary relative supersaturation and risk of stone recurrence in patients after urolithiasis surgery

 Published on 24/10/2025 |  Original article (Full-text)  | Aji Kaisaier et al. | BMC Urology 2025; 25(1): 258

Urolithiasis represents a significant global health burden, affecting approximately 10% of the population worldwide with recurrence rates reaching 50% within 5 years after the initial episode [1]. This high recurrence rate substantially decreases patients’ quality of life and imposes considerable...

E. coli as a uropathogen in patients with diabetes mellitus, its prevalence and antimicrobial resistance profile in Ethiopia: A systematic review and meta-analysis

 Published on 17/10/2025 |  Original article (Full-text)  | Tesfaye Nuhamin Alemayehu et al. | BMC Infectious Diseases 2025; 25(1): 1276

Urinary tract infection (UTI) defined as the presence of significant bacteria in urine specimen and refers to the proliferation of an infectious agent within the urogenital system with or without structural or functional abnormalities of the urinary tract that results in irritative and voiding symptoms...

Enfortumab vedotin promotes PD-L1 expression in urothelial carcinoma via NF-κB and STAT3 pathways highlighting mechanisms of immune evasion and potential for combination therapy

 Published on 10/10/2025 |  Original article (Full-text)  | Naito Hirohito et al. | BMC Immunology 2025; 26(1): 70

Urothelial carcinoma (UC) is diagnosed in nearly 600,000 new cases annually and is responsible for over 200,000 deaths worldwide, making it the ninth most common malignant neoplasm [1]. UC is the predominant histologic subtype of bladder cancer, accounting for 90% of bladder cancer cases [2]. and 7%...