Others Urological ConditionsArchives
Enfortumab vedotin promotes PD-L1 expression in urothelial carcinoma via NF-κB and STAT3 pathways highlighting mechanisms of immune evasion and potential for combination therapy
Others Urological Conditions 4 min.
Urothelial carcinoma (UC) is diagnosed in nearly 600,000 new cases annually and is responsible for over 200,000 deaths worldwide, making it the ninth most common malignant neoplasm [1]. UC is the predominant histologic subtype of bladder cancer, accounting for 90% of bladder cancer cases [2]. and 7%...
Clinicopathological and molecular correlates of clinical benefit from disitamab vedotin (RC48), a HER-2-targeting antibody-drug conjugate, in metastatic urothelial carcinoma: a multi-center, real-world study
Others Urological Conditions 5 min.
Urothelial carcinoma (UC), the malignant tumor arising from the epithelium lining the ureter, urinary bladder, and urethra, is a highly heterogeneous disease. Though for most patients, the standard care of neoadjuvant cisplatin-based chemotherapy followed by radical surgery, might curb the disease within...
The efficacy and safety of disitamab vedotin combined with immune checkpoint inhibitors in metastatic upper tract urothelial carcinoma: a multicenter real-world study
Others Urological Conditions 4 min.
Urothelial carcinoma (UC) is a type of cancer that arises from urothelial cells, occurring in both the upper urinary tract (renal pelvis and ureter) and lower urinary tract (bladder). It ranks as the fourth most commonly diagnosed cancer worldwide [1]. Upper tract UC (UTUC) accounted for 5–10%...
Virulence factors and outcomes in bacteremia caused by extended-spectrum β-lactamase-producing uropathogenic Escherichia coli ST131-H30Rx in a Swedish county
Others Urological Conditions 6 min.
The global burden of antimicrobial resistance (AMR) has been estimated to cause between 1.1 and 1.3 million deaths per year directly attributable to and between 4.2 and 5.2 million deaths associated with antibiotic-resistant bacteria [1]. Both globally and in Sweden, bacteremia and less severe...
