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Gastric DiseasesArchives

Laparoscopic versus open distal gastrectomy with d2 lymphadenectomy in treatment of locally T4A gastric cancer: the protocol of a randomized controlled trial

 Published on 08/05/2025 |  Original article (Full-text)  | Dat Tran Quang et al. | BMC Surgery 2025; 25(1): 193

Gastric cancer (GC) is one of the most common malignancies worldwide1, accounting for significant morbidity and mortality. Despite advancements in adjuvant therapies2, surgery remains the main curative treatment for gastric cancer. In recent years, laparoscopic gastrectomy (LG) has been increasingly...

Effect of perioperative probiotic supplements on the short-term clinical outcomes of patients undergoing laparoscopic or robotic radical gastrectomy after neoadjuvant chemotherapy: Study protocol for a multicenter randomized controlled trial (GISSG2023 - 01 Study)

 Published on 01/05/2025 |  Original article (Full-text)  | Liu Gan et al. | BMC Cancer 2025; 25(1): 775

Gastric cancer is a common malignant tumor accounting for 5.6% of new cases and causes 7.7% new deaths of all global cases of cancer [1]. Some patients are diagnosed with advanced gastric cancer (AGC) before receiving any anticancer therapy, which poses challenges to the treatment and prognosis of these...

Efficacy and safety of XELOX combined with neoadjuvant radiotherapy versus neoadjuvant chemotherapy in locally advanced gastric cancer

 Published on 24/04/2025 |  Original article (Full-text)  | Bu Shanshan et al. | BMC Cancer 2025; 25(1): 731

Gastric cancer (GC) is one of the most common malignant tumors in China. 70.8% of the patients were at the locally advanced stage when first diagnosed [1, 2–3]. The MAGIC [4] and FLOT4-AIO studies [5] confirm that preoperative neoadjuvant chemotherapy has significant downstaging effects for locally...

Innovative laparoscopic 'Tunnel' approach in managing hiatal hernia with gastroesophageal reflux disease: a retrospective study

 Published on 17/04/2025 |  Original article (Full-text)  | Feng Zhewen et al. | BMC Surgery 2025; 25(1): 154

Hiatal hernia (HH) refers to the condition where abdominal contents enter the thoracic cavity through the esophageal hiatus of the diaphragm and is considered a primary cause of gastroesophageal reflux disease (GERD) [1]. Laparoscopic repair of HH combined with anti-reflux surgery is suitable for patients...

Recent advances in acute gastrointestinal graft versus host disease (aGvHD): aspects of steroid-resistant disease

 Published on 10/04/2025 |  Original article (Full-text)  | Kujawska Joanna et al. | Annals of Hematology 2025; 104(2): 855-65

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a well-established curative therapy for various malignant and non-malignant hematological diseases [1]. Despite the continuous optimization of the allo-HSCT procedure, the success of allo-HSCT is limited by potentially life-threatening...