ColorectalArchives
Proteome profiling reveals early diagnostic biomarker candidates for colorectal cancer
Colorectal 7 min.
Colorectal cancer (CRC) ranks as the third most frequently diagnosed cancer and the second leading cause of cancer-related mortality on a global scale [1]. Early diagnosis is critical for improving patient outcomes, as the 5-year relative survival rate exceeds 90% in stages I–II but declines to...
A prospective investigation of early-onset colorectal cancer risk factors–pooled analysis of three large-scale European cohorts
Colorectal 6 min.
The incidence of colorectal cancer (CRC) in young adults (usually defined as a diagnosis prior to age 50 years) has increased over recent decades in many countries [1, 2, 3–4]. Data from the United States (U.S) shows that CRC incidence is also rising recently in the 50-54 year age group, mirroring...
Establishment of a microbial abundance prognostic model for colorectal cancer
Colorectal 8 min.
Colorectal cancer (CRC) ranks as the second leading cause of cancer mortality in the United States, with an increasingly younger age of onset being observed [1]. Among the millions of CRC patients newly diagnosed each year, nearly half were found to have metastasized or were on the brink of metastasis...
Evaluating quality indicators in colorectal cancer screening via fecal immunochemical tests: a five-year study from a developing country
Colorectal 7 min.
Colorectal cancer (CRC) is currently the third most frequently diagnosed cancer globally [1, 2]. The incidence of CRC is on the rise worldwide, particularly in developing countries such as Iran, where a Western lifestyle is becoming more common [2, 3]. Approximately 70% of sporadic CRCs develop from...
Dietary nitrosyl-heme from processed meats and its association with colorectal cancer risk: findings from the EPIC cohort study
Colorectal 4 min.
Colorectal cancer (CRC) is the third most common cancer globally, with over 1.93 million cases and 935,000 deaths each year. It is also the second leading cause of cancer-related deaths worldwide for both men and women [1]. Its incidence is expected to increase, mainly in people under 50 years of...
