ColorectalArchives
Clinical and epidemiological profile of patients with colorectal cancer in Bhutan: a cross-sectional study
Colorectal 4 min.
Colorectal cancer is the third most common malignancy and the third leading cause of cancer-related deaths worldwide [1]. Globally, the burden of colorectal cancer cases has more than doubled, from 0.84 million to 2.17 million, and deaths increased from 0.51 million to 1.09 million...
Prognostic importance of CD47 expression on survival of colorectal cancer
Colorectal 4 min.
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in both sexes and the second leading cause of death in the United States [1]. Despite new advances in the treatment of CRC, the prognosis of metastatic CRC (mCRC) remains poor, with a 5-year relative survival rate of 14% [2]. Despite...
The novel role of DUSP4 in suppressing ferroptosis and promoting cytotoxicity of CD8+ T cells in MSI colorectal cancer
Colorectal 8 min.
Colorectal cancer (CRC) ranks as the second leading cause of cancer death in the world [1]. As a heterogeneous disease, one of the major carcinogenetic pathways of CRC is microsatellite instability (MSI) [2]. MSI CRC is a subtype of cancer that is characterised by the presence of a defective DNA mismatch...
The single-cell atlas of colorectal cancer reveals cellular heterogeneity and key molecular features of the tumor immune microenvironment
Colorectal 9 min.
Colorectal cancer (CRC) is one of the most common and deadly malignancies worldwide, with its incidence increasing with age [1]. Although traditional treatments like surgery and chemotherapy have had some success, many patients still face poor prognosis due to disease recurrence and metastasis [2]. In...
