Hereditary cancer syndromes are commonly characterized by notably increased lifetime susceptibilities to multiple cancers, frequently manifesting at a young age [1]. The identification and detection of individuals with specific inherited predispositions to cancer have profound implications for both patients...
It is estimated that by 2022, approximately 4.82 million new instances of cancer and 3.21 million fatalities due to cancer will occur in China. Colorectal cancer (CRC) accounts for 12.3% of the total cancer incidence and 9.6% of the cancer-related deaths [1, 2]. The incidence and mortality rates of CRC,...
According to the latest global cancer statistics report, colorectal cancer (CRC) maintains a significant burden worldwide, ranking as the third most commonly diagnosed cancer with 1.92 million new cases and the second leading cause of cancer-related mortality with 0.9 million deaths [1]. This epidemiological...
Histone modifications, especially the lysine acetylation, have drawn increasing attention in cancer research area. The aim of this research is to explore the molecular mechanisms underlying the regulation of lysine acetyltransferase 2 A (KAT2A) on colorectal cancer (CRC). Clinical samples were...