
Metal-based drugs, such as the platinum-derived compounds cisplatin and oxaliplatin, are routinely used in cancer therapy. Currently, among these, only oxaliplatin has demonstrated significant efficacy in colorectal cancer (CRC). This urges the necessity of developing more effective anticancer agents....

Chemotherapy-induced nausea and vomiting, together with depression and anxiety, are common and distressing complications in patients with colorectal cancer that seriously impair quality of life and treatment adherence. This study explored the efficacy of mindfulness-based stress reduction (MBSR) in relieving...

We examined the association between residential segregation and late-stage colorectal cancer (CRC) in the United States. The restricted-use United States Cancer Statistics database was used to identify all CRC cases diagnosed during 2009 to 2017. Late-stage CRC was determined according to the presence...

This study aimed to investigate the association of prediagnostic phytosterol intake (total phytosterols, β-sitosterol, campesterol, stigmasterol, β-sitostanol, and campestanol) with colorectal cancer (CRC)-specific and overall survival and to explore the potential mediating role of systemic...

Increasing incidence rates of early-onset colorectal cancer (ie, <50 years of age) have been reported across multiple countries. We investigated long-term cancer incidence data from 1995 or earlier from Australia, Canada, England, and the United States separately by sex. Estimated annual percentage...