ColorectalArchives
Sacituzumab govitecan in colorectal cancer: clinical evidence and future directions
Colorectal 1 min.
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide and continues to pose a significant global health burden. Despite therapeutic advances, the prognosis remains poor due to limited treatment options, resistance to therapy, and frequent metastasis. Standard treatment...
Safety of fruquintinib mono- and combo therapy in metastatic colorectal cancer: real-world subgroup analysis from China
Colorectal 1 min.
Fruquintinib, a highly selective vascular endothelial growth factor receptor 1, 2, 3 inhibitors, has demonstrated significant efficacy in phase III trials for metastatic colorectal cancer (mCRC). However, real-world evidence is essential to confirm its safety profile across diverse treatment settings....
Antitumor activity of silver (Ag) complexes in colorectal cancer cells by oxidative stress and apoptosis induction
Colorectal 1 min.
Metal-based drugs, such as the platinum-derived compounds cisplatin and oxaliplatin, are routinely used in cancer therapy. Currently, among these, only oxaliplatin has demonstrated significant efficacy in colorectal cancer (CRC). This urges the necessity of developing more effective anticancer agents....
The effect of mindfulness-based stress reduction on chemotherapy-related physical and psychological distress in colorectal cancer patients: a retrospective cohort study
Colorectal 1 min.
Chemotherapy-induced nausea and vomiting, together with depression and anxiety, are common and distressing complications in patients with colorectal cancer that seriously impair quality of life and treatment adherence. This study explored the efficacy of mindfulness-based stress reduction (MBSR) in relieving...
Residential segregation and late-stage colorectal cancer in the United States: a population-based study of 1.2 million adults
Colorectal 1 min.
We examined the association between residential segregation and late-stage colorectal cancer (CRC) in the United States. The restricted-use United States Cancer Statistics database was used to identify all CRC cases diagnosed during 2009 to 2017. Late-stage CRC was determined according to the presence...
