Immunogenicity and Safety of Two-dose Schedules With Different Intervals of an ORF7-deficient Live Vaccine Candidate for Varicella: A Randomized, Double-blind, Controlled, Phase 2b Trial.

Vaccines

 1 min.

Current Oka strain varicella vaccines are generally safe but may cause latent neuronal infections leading to herpes zoster in some vaccinees. A novel v7D candidate vaccine has been developed to prevent varicella and reduce these risks. Methods: This randomized, double-blind, controlled, phase 2b clinical...