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Long-term trends in reporting of cardiac adverse drug reactions to COVID-19 vaccines - an exploratory analysis of the EudraVigilance database
Vaccines
 6 min.

 Published on 20/11/2025 |  Original article (Full-text)  | Nazar Wojciech et al. | BMC Infectious Diseases 2025; 25(1): 1584

Vaccines against Coronavirus disease 2019 (COVID-19) are confirmed to be highly effective in preventing COVID-19 infections [1, 2, 3–4]. Vaccinating reduces the risk of symptomatic infection, hospitalisations, including in intensive care units, and death [1, 2, 3, 4–5]. The European Medicines...

Ageing with HIV-1: immunological challenges for effective vaccination
Vaccines
 5 min.

 Published on 13/11/2025 |  Original article (Full-text)  | Saint-Charles Pauline et al. | Immunity & Ageing 2025; 22(1): 48

By 2050, the proportion of the world’s population aged 60 and above is expected to increase from 12% to 22%, and the number of people over 80 years old is projected to triple between 2020 and 2050 [1]. These estimations illustrate the need to address ageing as a significant public health issue...

The influence of structured physical activity on vaccination response from adults to older individuals: a systematic review on the Immunoinflammatory crosstalk of COVID-19
Vaccines
 7 min.

 Published on 06/11/2025 |  Original article (Full-text)  | Palotino-Ferreira Bruna Maria et al. | Immunity & Ageing 2025; 22(1): 44

The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has brought unprecedented challenges to global healthcare systems and social structures [1]. Although the development and distribution of vaccines have provided a glimmer of light at the end of the tunnel, the full comprehension of the determinants...

OmpA virulence factor, a promising conserved vaccine candidate against Acinetobacter baumannii, could trigger autoreactive immune responses in susceptible population
Vaccines
 9 min.

 Published on 30/10/2025 |  Original article (Full-text)  | Zanoos Kobra Ahmadi et al. | BMC Immunology 2025; 26(1): 85

Epitope mimicry is suggested as a mechanism to trigger autoimmune responses. These autoimmune responses could be associated with microbial infections and vaccinations [1]. Autoimmune responses could be deemed significant implications for the safety of vaccine candidates, which is considered one of the...

Physicians’ knowledge of, and willingness to encourage caregivers to partake in the RTS S/AS01 and R21 matrix M malaria vaccines roll out – a national survey in Nigeria
Vaccines
 4 min.

 Published on 23/10/2025 |  Original article (Full-text)  | Oboh Mary Aigbiremo et al. | BMC Infectious Diseases 2025; 25(1): 1345

The malaria parasite caused by Plasmodium falciparum continues to pose a huge public health challenge in tropical and sub-tropical regions of the world [1], and morbidity and mortality resulting from falciparum species represent the highest of all the Plasmodium species (World Health...