VaccinesArchives
Safety, immunogenicity, persistence and dose evaluation of the CS-2034 mRNA COVID-19 vaccine: a phase II randomized controlled trial in healthy Chinese adults
Vaccines 7 min.
SARS-CoV-2 is an extremely contagious single-stranded RNA virus that has rapidly spread worldwide, causing COVID-19. Vaccination has been pivotal in mitigating its impact. Although mRNA vaccine technology is relatively new, it offers distinct advantages over other vaccine platforms, including rapid manufacturing,...
Long-term trends in reporting of cardiac adverse drug reactions to COVID-19 vaccines - an exploratory analysis of the EudraVigilance database
Vaccines 6 min.
Vaccines against Coronavirus disease 2019 (COVID-19) are confirmed to be highly effective in preventing COVID-19 infections [1, 2, 3–4]. Vaccinating reduces the risk of symptomatic infection, hospitalisations, including in intensive care units, and death [1, 2, 3, 4–5]. The European Medicines...
Ageing with HIV-1: immunological challenges for effective vaccination
Vaccines 5 min.
By 2050, the proportion of the world’s population aged 60 and above is expected to increase from 12% to 22%, and the number of people over 80 years old is projected to triple between 2020 and 2050 [1]. These estimations illustrate the need to address ageing as a significant public health issue...
The influence of structured physical activity on vaccination response from adults to older individuals: a systematic review on the Immunoinflammatory crosstalk of COVID-19
Vaccines 7 min.
The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has brought unprecedented challenges to global healthcare systems and social structures [1]. Although the development and distribution of vaccines have provided a glimmer of light at the end of the tunnel, the full comprehension of the determinants...
OmpA virulence factor, a promising conserved vaccine candidate against Acinetobacter baumannii, could trigger autoreactive immune responses in susceptible population
Vaccines 9 min.
Epitope mimicry is suggested as a mechanism to trigger autoimmune responses. These autoimmune responses could be associated with microbial infections and vaccinations [1]. Autoimmune responses could be deemed significant implications for the safety of vaccine candidates, which is considered one of the...
