VaccinesArchives
Imprecision in tuberculosis infection outcomes: implications for non-inferiority vaccine trials
Vaccines 1 min.
Randomized trials comparing new vaccines against tuberculosis for use in neonates and infants, for whom Bacille Calmette-Guérin vaccination is established practice, are using tuberculosis infection as the primary endpoint in a non-inferiority design. Markers of tuberculosis infection have imperfect...
Comparing standard versus intensified pneumococcal vaccination regimens in patients with inflammatory bowel disease on biologics: a prospective, multicenter, randomized, open-label study
Vaccines 1 min.
Pneumococcal vaccination is essential for patients with inflammatory bowel diseases (IBD), but its efficacy is reduced in those on antitumor necrosis factor (TNF) or immunosuppressive therapy. This study compared immune responses to standard versus intensified pneumococcal vaccination strategies in IBD...
Knowledge on modes of hepatitis B transmission and the practice of family screening and vaccination among patients with chronic hepatitis B infection at a tertiary center in Ethiopia
Vaccines 5 min.
Hepatitis B infection remains an important global public health problem with significant morbidity and mortality. It is estimated that 2 billion people have evidence of past or present infection with hepatitis B virus (HBV) worldwide [1, 2]. The World Health Organization (WHO) estimated that 296 million...
COVID-19 vaccine confidence among parents of racially diverse children aged 0–12 years old in Canada: The role of major experience of racial discrimination, health literacy, and conspiracy beliefs
Vaccines 1 min.
The success of COVID-19 vaccination is linked to trust, hesitancy, and confidence. Racial discrimination impacts vaccine hesitancy and trust, particularly in racialized groups. This study investigates factors influencing COVID-19 vaccine confidence among Canadian parents from different racial groups,...
Pneumococcal vaccine for prevention of acute otitis media in children: a meta-analysis
Vaccines 4 min.
Streptococcus pneumoniae is a major pediatric pathogen worldwide and a major cause of illness and death in children younger than five years. Its clinical spectrum ranges from invasive diseases—such as meningitis and septicemia—to noninvasive infections, including pneumonia, with mucosal illnesses...
